2,318 research outputs found
Survey of psychiatrists on forensic psychiatric assessments in Singapore
No full textIntroduction: The quality of forensic psychiatry assessments in Singapore has come under recent criticism from the judiciary resulting in a loss of confidence in forensic psychiatric assessments. There is no local published standards or practice guidelines for forensic psychiatric assessments. We set out to survey local psychiatrists on various key aspects of local forensic psychiatric assessments. Methods: A survey was developed by two local senior psychiatrists with extensive experience in forensic psychiatry. It was sent out electronically to all Singapore registered psychiatrists. Results: The response rate was 33.6% (48 of 143 psychiatrists). Respondents agreed that risk assessment and management, capacity and competence assessments and critical appraisal of symptoms were specific forensic psychiatry skill sets. There was also a consensus that separation of treating versus assessment roles and an independent panel of psychiatrist would be useful. There was no clear consensus on which psychiatrists should perform forensic assessments or if language used and time taken for assessments were important. The estimated time for assessments ranged from 1.9 hour (SD 1.3) to 9.1 hours (SD 5.4) with time required for criminal > civil > capacity assessments. Private sector psychiatrists were more likely than public sector psychiatrists to feel that forensic psychiatric qualifications were not necessary to conduct forensic assessments. Conclusion: There is a consensus in the local psychiatric community on various key aspects of forensic psychiatric assessment. Stakeholders in forensic assessments should begin a dialogue on the way forward for forensic psychiatric assessments in Singapore
Association of electroconvulsive therapy with psychiatric readmissions in Singapore tertiary mood disorder unit
No full textMirror Readmission Study of the Association of Electroconvulsive Therapy With 1-Year Mood Disorder Readmissions in a Tertiary Mood Disorder Unit
No full textTor over QUIC
No full textTor is the most popular tool for anonymous online communication. However, the performance of Tor's volunteer-run network is suboptimal when network congestion occurs. Within Tor, many connections are multiplexed over a single TCP connection between relays, which causes a head-of-line blocking problem, degrading relay performance. In this thesis, Tor's TCP transport layer protocol is replaced by QUIC, a UDP-based protocol that natively supports multiplexing streams asynchronously, effectively solving head-of-line blocking. Its performance is evaluated within various network environments through Containernet, a flexible Docker-based network test bed that allows for simple reproduction of results. Along with testing multiple congestion control algorithms, the impact of using Hystart++ within Tor over QUIC is evaluated. It is found that QUIC over Tor can perform up to 50% better in time to last byte performance than vanilla Tor in a realistic network environment, while featuring more consistent time to first byte performance. Additionally, the evaluations shows that throughput consistency and fairness amongst downloaders are improved as well, Besides offering improved performance, Tor over QUIC is designed with deployability and security in mind. This makes QUIC an attractive replacement as Tor's transport layer protol.Computer Scienc
TOR Is required for the retrograde regulation of synaptic homeostasis at the drosophila neuromuscular junction
No full textHomeostatic mechanisms operate to stabilize synaptic function; however, we know little about how they are regulated. Exploiting Drosophila genetics, we have uncovered a critical role for the target of rapamycin (TOR) in the regulation of synaptic homeostasis at the Drosophila larval neuromuscular junction. Loss of postsynaptic TOR disrupts a retrograde compensatory enhancement in neurotransmitter release that is normally triggered by a reduction in postsynaptic glutamate receptor activity. Moreover, postsynaptic overexpression of TOR or a phosphomimetic form of S6 ribosomal protein kinase, a common target of TOR, can trigger a strong retrograde increase in neurotransmitter release. Interestingly, heterozygosity for eIF4E, a critical component of the cap-binding protein complex, blocks the retrograde signal in all these cases. Our findings suggest that cap-dependent translation under the control of TOR plays a critical role in establishing the activity dependent homeostatic response at the NMJ
Adding QUIC support to the Tor network
No full textPrivacy in the Internet is under attack by governments and companies indiscriminately spying on everyone. The anonymity network Tor is a solution to restore some privacy, however, Tor is slow in both bandwidth and latency. It uses a TCP-based connection to multiplex different circuits between nodes and this causes different independent circuits to interfere with each other. To solve this, we propose a transport layer implementation using the UDP-based protocol QUIC, as it allows independent streams over a single connection. We built a Tor prototype that uses this protocol and evaluated its performance using a custom network simulator, as existing simulators were shown to be incompatible. We show that the QUIC-based implementation increased performance in several of the use case scenarios, mainly outperforming on the ‘time to first byte’ metric.Electrical Engineering | Embedded System
The Impact of Electroconvulsive Therapy on Negative Symptoms in Schizophrenia and Their Association with Clinical Outcomes
No full textObjective: The treatment efficacy of electroconvulsive therapy (ECT) for negative symptoms amongst patients with schizophrenia remains unclear. In this study, we aim to examine the effects of ECT on negative symptoms in schizophrenia and their association with other clinical outcomes, including cognition and function. Methods: This is a retrospective data analysis of patients with schizophrenia/schizoaffective disorder treated with ECT at the Institute of Mental Health (IMH), Singapore, between January 2016 and December 2019. Clinical outcomes were assessed by the Brief Psychiatric Rating Scale (BPRS), the Montreal Cognitive Assessment (MoCA), and Global Assessment of Function (GAF). Changes in scores were compared with repeated measures analysis of variance. Sequential structural modelling was utilized to examine the pathway relationships between changes in negative symptoms, global functioning, and cognition functioning after ECT. Results: A total of 340 patients were analysed. Hence, 196 (57.6%), 53 (15.5%), and 91 (26.7%) showed improvements, no change, and deterioration in negative symptoms, respectively. ECT-induced improvement of negative symptoms was significantly associated with improvement of global functioning (direct effect correlation coefficient (r): −0.496; se: 0.152; p = 0.001) and cognition function (indirect effect r: −0.077; se: 0.037; p = 0.035). Moreover, having capacity to consent, more severe baseline negative symptoms, lithium prescription, and an indirect effect of voluntary admission status via consent capacity predicted ECT associated negative symptoms improvement. Conclusion: ECT is generally associated with improvements of negative symptoms in people with schizophrenia, which correlate with improvements of overall function. Possible novel clinical predictors of negative symptom improvement have been identified and will require further research and validation
Measuring accessibility of popular websites while using Tor
No full textTor is an anonymity network used by a vast number of users in order to protect their privacy on the internet. It should not come as a surprise that this service is also used for abuse such as Denial of service attacks and other malicious activities because of the anonymity it provides. For protecting themselves from this abuse, websites block Tor in various ways. We investigate the extent and frequency of this kind of blocking by requesting the Alexa top 1000 websites with and without Tor with the objective of highlighting the differential treatment observed by privacy-minded users. We build upon existing studies by using diverse metrics to measure discrimination and by extending our search to three sub pages of websites for detecting sophisticated blocking. We find at least 25.8% of the Alexa top 1000 websites discriminating on the home page against Tor users as opposed to 20.03% observed in previous studies. This number rises to 31.7% after including the three sub pages. We also discover new types of blocks such as Tor users being served old or different versions of websites. We categorize the blocked websites and find that Online Shopping and Finance/ Banking categories discriminate most against Tor while Social Networking sites and Search Engines discriminate the least.CSE3000 Research ProjectComputer Science and Engineerin
Products on Tor
No full textIn 1974 work establishing the collapse of certain Eilenberg-Moore spectral
sequences, Munkholm constructs, in passing, a bilinear multiplication operation
on Tor of a triple of -algebras. In 2020, the present author,
pursuing a multiplicative collapse result extending Munkholm's, studied a
variant of this product, without actually showing it agrees with Munkholm's. In
2019, Franz had defined a weak product on the two-sided bar construction of a
triple of -algebras under similar hypotheses, with which this author
proved a related collapse result, but without investigating the properties of
the induced product on Tor.
The present work demonstrates that the two products on Tor agree and are
induced by the product of Franz.Comment: 19 pages, comments welcom
- …
