351 research outputs found

    SRAM-based Physically Unclonable Function using Lightweight Hamming-Code Fuzzy Extractor for Energy Harvesting Beat Sensors

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    Batteryless energy harvesting IoT sensor nodes such as beat sensors can be deployed in millions without the need to replace batteries. They are ultra-low-power and cost-effective wireless sensor nodes without the maintenance cost and can work for 24 hours/365 days. However, they were not equipped with security mechanisms to protect user data. Data encryption and authentication can be used to secure beat sensor applications, but generating a secure cryptographic key is challenging. In this paper, we proposed an SRAM-based Physically Unclonable Function (PUF) combining a high-reliability bit selection algorithm with a lightweight error-correcting code to generate reliable secure keys for data encryption. The system employs a feature of beat sensors, in which the microcontroller is powered on to transmit the ID signals and then powered off. This fits the SRAM-based PUF requirement, which needs the SRAM to be powered off to read out its random values. The proposed system has been evaluated on STM32 Cortex M0+ micro controllers and has been implemented to protect important data on beat sensors

    Inhibition of long chain fatty acyl-CoA synthetase (ACSL) and ischemia reperfusion injury

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    Various triacsin C analogs, containing different alkenyl chains and carboxylic acid bioisoteres including 4-aminobenzoic acid, isothiazolidine dioxide, hydroxylamine, hydroxytriazene, and oxadiazolidine dione, were synthesized and their inhibitions of long chain fatty acyl-CoA synthetase (ACSL) were examined. Two methods, a cell-based assay of ACSL activity and an in situ [¹⁴C]-palmitate incorporation into extractable lipids were used to study the inhibition. Using an in vivo leukocyte recruitment inhibition protocol, the translocation of one or more cell adhesion molecules from the cytoplasm to the plasma membrane on either the endothelium or leukocyte or both was inhibited by inhibitors 1, 9, and triacsin C. The results suggest that inhibition of ACSL may attenuate the vascular inflammatory component associated with ischemia reperfusion injury and lead to a decrease of infarct expansion

    Love’s Crystal

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    The story of the fatal love of a poor fisherman for the daughter of a wealthy mandarin is widely known throughout Vietnam. This paper traces its Chinese origin and its retelling in two forms, a long and a short version, by the Francophone Vietnamese author Pham Duy Khiem (1908–1974). It suggests that rewriting in this way helped Khiem develop the sparse, melancholy style that is characteristic of mature work

    Self-Organized Plasmonic Nanowire Arrays Coated with Ultrathin TiO2 Films for Photoelectrochemical Energy Storage

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    The strategic field of renewable energy production and storage requires novel nanoscale platforms that can feature competitive solar energy conversion properties. Photochemical reactions that promote energy storage, such as water splitting and oxygen-hydrogen evolution reactions, play a crucial role in this context. Here, we demonstrate a novel photoelectrochemical device based on large-area (cm(2)) self-organized Au nanowire (NW) arrays, uniformly coated with ultrathin TiO2 films. The NW arrays act both as transparent nanoelectrodes and as a plasmonic metasurface that resonantly enhances the very weak visible photocurrent generated by a prototype photoelectrochemical oxygen evolution reaction. We demonstrate a polarization-sensitive plasmon-enhanced photocurrent that reaches a gain of about 3.8 in the visible spectral range. This highlights the potential of our novel nanopatterned plasmonic platform in photochemistry and energy storage

    Plasmonic and 2D-TMD nanoarrays for large-scale photon harvesting and enhanced molecular photo-bleaching

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    The urgent environmental and energy challenges require novel solutions for efficient light harvesting and conversion in new-generation ultra-thin devices. Plasmonic nanoantennas and flat optics nanogratings can promote light matter interaction at the nanoscale being very attractive for ultra-thin photonics and sensing applications. In this work we developed two light trapping solutions based on large-scale nanomaterials. The first system is a large-scale (cm2) plasmonic metasurface based on self-organized gold nanostripes. The second is based on the periodic re-shaping of ultra-thin semiconducting MoS2 layers forming large-area flat-optics nanogratings. Under this condition Rayleigh Anomalies can be resonantly excited thus promoting in-plane light confinement and photon absorption into the few-layers material. To demonstrate the impact of these nanopatterned systems in photon harvesting we probed their efficiency into a prototypal photochemical reaction: the photo-bleaching of Methylene Blue (MB). We demonstrate the resonant enhancement of the photo-bleaching of these polluting dye molecules promoted either by the localized plasmon resonance in Au nanostripes or by the Rayleigh Anomaly in flat-optics MoS2 nanogratings. We investigate this effect through a quantitative analysis of the solution photodissociation induced by a monochromatic light. These results show the strong potential of flat-optics templates for light-harvesting and energy conversion in ultra-thin photonic devices

    On the approximation of the SABR with mean reversion model : a probabilistic approach

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    In this paper, we study the stochastic alpha beta rho with mean reversion model (SABR-MR). We first compare the SABR model with the SABR-MR model in terms of future volatility to point out the fundamental difference in the models’ dynamics. We then derive an efficient probabilistic approximation for the SABR-MR model to price European options. Similar to the method derived in Kennedy, J. E., Mitra, S., & Pham, D. (2012). On the approximation of the SABR model: A probabilistic approach. Applied Mathematical Finance, 19(6), 553–586., we focus on capturing the terminal distribution of the underlying asset (conditional on the terminal volatility) to arrive at the implied volatilities of the corresponding European options for all strikes and maturities. Our resulting method allows us to work with a wide range of parameters that cover the long-dated option and different market conditions

    Novel triacsin C analogs as potential antivirals against rotavirus infections

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    Recently our group has demonstrated that cellular triglycerides (TG) levels play an important role in rotavirus replication. In this study, we further examined the roles of the key enzymes for TG synthesis (lipogenesis) in the replication of rotaviruses by using inhibitors of fatty acid synthase, long chain fatty acid acyl-CoA synthetase (ACSL), and diacylglycerol acyltransferase and acyl-CoA:cholesterol acyltransferase in association with lipid droplets of which TG is a major component. Triacsin C, a natural ACSL inhibitor from Streptomyces aureofaciens, was found to be highly effective against rotavirus replication. Thus, novel triacsin C analogs were synthesized and evaluated for their efficacies against the replication of rotaviruses in cells. Many of the analogs significantly reduced rotavirus replication, and one analog (1e) was highly effective at a nanomolar concentration range (ED[subscript 50] 0.1 μM) with a high therapeutic index in cell culture. Our results suggest a crucial role of lipid metabolism in rotavirus replication, and triacsin C and/or its analogs as potential therapeutic options for rotavirus infections
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