680 research outputs found
Motive und Motivationen als Grundlage menschlichen Verhaltens – Überlegungen zu einer integrativen Motivationstheorie
No full textDie Untersuchungen der Autorin zur Motivation führen zu dem Schluss, dass Grundmotive im Menschen genetisch angelegt sind. Diese sind implizit in seinem Menschen- und Weltbild vorhanden und werden in situativen Motivationsprozessen aktualisiert. Das Motiv der Hilfeleistung, das in therapeutischen oder beraterischen Prozessen beim Therapeuten aktiviert ist, findet ein Gegenüber im Motiv der Suche nach Hilfe beim Klienten. Beide Seiten folgen einem, von der Autorin dargestellten intersubjektiven Motivationsprozess.The author’s research focuses on the origin and development of motives and moti¬vation with special emphasis on the motive of helpfulness in therapy or consulting. Helpfulness is an essential of the human character. It determines our concepts of the world and of mankind. From an integrative point of view the author discusses the origins of motives in man and develops a structural model of the process of motivation and behaviour of both, client and therapist.https://www.fpi-publikation.de/polyloge/13-2012-jaekel-brigitte-motive-und-motivationen-als-grundlage-menschlichen-verhaltens/peerReviewedpublishedVersio
Edgar and Brigitte Bodenheimer Collection 1897-1992, 2011 1920-1983
No full textThe Edgar and Brigitte Bodenheimer Collection documents the professional and personal life of law professor Edgar Bodenheimer as well as that of his wife, Brigitte Bodenheimer (née Levy). The collection contains documentation on their early legal work during the 1940s, Edgar's participation in the Nuremberg Trials, and postwar work as professors, as well as material on their daily lives and other family members. The collection includes a copious amount of correspondence, lecture texts, certificates and diplomas, diaries and notebooks, newspaper clippings, teaching material, poetry, a friendship album, and other papers.Original order in 5 boxes: Box 1: Edgar and Brigitte Bodenheimer: journals, poems, documents. Box 2: Edgar Bodenheimer: speeches & talks, CV, bibligraphies, teaching materials, reviews of E.B.'s books. Box 3: Edgar Bodenheimer professional correspondence. Box 4a: Edgar Bodenheimer personal correspondence. Box 4b: Edgar Bodenheimer personal correspondence.A book about Edgar and Brigitte Bodenheimer by their daughter Rosemarie Bodenheimer is available in the LBI Library: "Edgar and Brigitte: a German Jewish passage to America". This book was written using the documents in this collection.Two books by Edgar Bodenheimer with his extensive handwritten notes were removed to the LBI Library. Photocopies of these notes were retained in the collection and will be found in Series III.Edgar Bodenheimer was born in Berlin on March 14, 1908, the son of the bank director Siegmund Bodenheimer and his wife Rosa (called Rosi, née Maass). He studied law and political science at various German and Swiss universities, acquiring his Doctor of Laws from the University of Heidelberg in 1933. In 1934 Edgar Bodenheimer immigrated to the United States, where he found a position in a New York City law office.Brigitte M. Levy was the daughter of Ernst Levy, a professor and scholar of Roman Law at the University of Heidelberg, and Marie Levy (née Wolff). After studies at various German universities, she received her doctoral degree in jurisprudence from the University of Heidelberg in 1934 after have immigrating to New York, where she continued her studies at Columbia University. In 1935 Edgar Bodenheimer and Brigitte M. Levy married. (They eventually had three children: Peter became a professor of astrophysics at the University of California; Thomas became a physician; and Rosemarie became an author and professor of English literature at Boston College.In 1935 the couple moved to Seattle, Washington, where they both studied law at the University of Washington. Edgar Bodenheimer joined the Washington Bar Association in 1939 once he had become a citizen. The following year Edgar Bodenheimer received a Bachelor of Arts Degree in Law Librarianship. His book ‘Jurisprudence’ was published in 1940; many other books followed until 1962. In 1942 the Bodenheimers moved to Washington, D.C., working in various official positions. In 1945 Edgar joined the prosecuting team at the Nuremberg Trials.In 1946 Edgar Bodenheimer took a position at the University of Utah in Salt Lake City; in 1951 he was made full professor and held the position until his departure in 1966. Brigitte Bodenheimer worked primarily in the fields of divorce, marriage, and juvenile court legislation. In 1964 she also became a full-time professor at the University of Utah.In 1966 Edgar Bodenheimer became professor of law at the University of California at Davis. In 1975 he became Professor Emeritus. Brigitte Bodenheimer became a full professor at Davis in 1972; in 1979 she became Professor Emeritus. She died in 1981 at the age of 69.Edgar Bodenheimer held visiting professorships at several universities in Germany and in the U.S. In 1975 he was named an Outstanding Educator of America. He died in 1991 in Davis, California, survived by his second wife, Brigitte née Schoenberg.Finding aid available onlineProcesseddigitize
Ambivalenzen des Alltags : Neuorientierungen fur eine Theorie des Politischen /
No full textDie politische Theorie ist gegenwärtig - nicht zuletzt in Reaktion auf veränderte gesellschaftliche Verhältnisse - durch eine angeregte Diskussion über das Politische geprägt. Brigitte Bargetz greift diese aktuellen Debatten auf und schlägt mit dem Konzep.Political theory is currently marked by lively discussion, not least in response to changing social conditions. Brigitte Bargetz siezes on these current debates and puts forward a new direction of political thought using the concept of the everyday: Following Henri Lefebvre, Agnes Heller, and Lawrence Grossberg, she outlines a complex theory of everyday life which allows the perception of the everyday as an ambivalent political battleground between domination and resistance, providing the starting point for a practical theory of politics beyond the state.Die politische Theorie ist gegenwärtig - nicht zuletzt in Reaktion auf veränderte gesellschaftliche Verhältnisse - durch eine angeregte Diskussion über das Politische geprägt. Brigitte Bargetz greift diese aktuellen Debatten auf und schlägt mit dem Konzep.Political theory is currently marked by lively discussion, not least in response to changing social conditions. Brigitte Bargetz siezes on these current debates and puts forward a new direction of political thought using the concept of the everyday: Following Henri Lefebvre, Agnes Heller, and Lawrence Grossberg, she outlines a complex theory of everyday life which allows the perception of the everyday as an ambivalent political battleground between domination and resistance, providing the starting point for a practical theory of politics beyond the state.Includes bibliographical references.JSTO
Implication de la Calréticuline et de CRMP4 dans la dégénérescence des motoneurones dans la Sclérose Latérale Amyotrophique
No full textLa Sclérose Latérale Amyotrophique se caractérise par la perte sélective de motoneurones (MNs) du cortex, du tronc cérébral et de la moelle épinière. Les souris surexprimant le gène humain muté codant pour la superoxide dismutase 1 (mSOD1) constitue un bon modèle d'étude. Les MNs mSOD1 présentent une hypersensibilité à la mort après activation du récepteur Fas et la production d'oxyde nitrique (NO). Notre étude protéomique a identifié deux effecteurs du NO, la calréticuline (CRT) et CRMP4. CRT est une protéine chaperonne de stockage du calcium dans le réticulum endoplasmique. Nous montrons que, in vivo, CRT diminue de moitié dans une sous population de MNs mSOD1 dits vulnérables, car dégénérant les premiers. Sa diminution est nécessaire et suffisante pour induire la mort des MNs mSOD1 en activant le stress du RE. CRMP4 est une protéine de régulation de la croissance axonale, qui augmente in vivo dans les MNs mSOD1 à un stade pré-symptomatique. Sa surexpression est suffisante pour induire une dénervation périphérique et la dégénérescence de MNs mSOD1. Nos résultats mettent en évidence CRT et CRMP4 comme étant deux cibles thérapeutiques potentielles dans la SLA.Amyotrophic Lateral Sclerosis (ALS) is characterized by the selective degeneration of upper and lower motoneurons (MNs). The most common familial form and best characterized mouse model of ALS is linked to mutations in the gene coding for the superoxide dismutase 1 (mSOD1). MNs expressing mSOD1 show an increased sensitivity to the death induced by Fas/NO activation. Our proteomic study identified two downstream effectors of NO, Calreticulin (CRT) and CRMP4. CRT is a chaperone-calcium-binding protein of the endoplasmic reticulum, which is decreased two-fold in vivo, in an early degenerating MNs sub-population, named vulnerable. The decrease in CRT expression is both necessary and sufficient to kill mSOD1 MNs through ER stress activation. CRMP4 is a neurite outgrowth regulator which expression is increased in vivo in mSOD1 MNs at a presymptomatic stage. CRMP4 overexpression is sufficient to induce peripheral denervation and, through a dying-back effect, to kill mSOD1 MNs. Our results point out CRT and CRMP-4 as two potential therapeutic targets for ALS
Le travail du coton chez les Ema de Timor portugais
No full text2. Brigitte Clamagirand (C.N.R.S., Paris) telah dua kali tinggal dalam watu jang lama di daerah penduduk Kemak, Timor Portugis, untuk mengadakan penjelidikan. Penulis memaparkan berbagai tahap pengerdjaan kapas, jang hanja dikerdjakan oleh kaum wanita; untuk tiap tahap jang penting, mulai dari membersihkan kapas dari bidji2-nja sampai memberi warna (proses ikai) dan waktu penenunan, penulis memberikan semua istilah tehniknja beserta photo dan skemanja.(2) Brigitte Clamagirand (CRNS, Paris) has made two field trips of long duration among the Ema (Kemak) of Portuguese Timor; she presents us with the diverse phases of working of cotton, which, there, is exclusively the work of women. For each of the principal phases, from the gining of the wad, to the tinting (ikat process), to the weaving (with a back strap loom), the author gives us the technical terms with photographs and schémas.Clamagirand Brigitte. Le travail du coton chez les Ema de Timor portugais. In: Archipel, volume 3, 1972. pp. 55-80
Recenzja: Wiedeński okres w życiu Adolfa Hitlera w ujęciu Brigitte Hamann i Augusta Kubizka
No full text THE VIENNESE PERIOD IN ADOLF HITLER’S LIFE AS PRESENTED BY BRIGITTE HAMANN AND AUGUST KUBIZEKThe article discusses the literature and the findings concerning the relatively least explored questions concerning Adolf Hitler, namely those of his youth. As the author stresses, just over a dec­ade ago Polish readers interested in the Hitler phenomenon knew much less than they do now. Thanks to several books recently published in Poland they have had a chance to considerably expand their knowledge. The present author points to two figures, Brigitte Hamann and August Kubizek, focusing on the similarities and differences in their approach to this period of Hitler’s life. THE VIENNESE PERIOD IN ADOLF HITLER’S LIFE AS PRESENTED BY BRIGITTE HAMANN AND AUGUST KUBIZEKThe article discusses the literature and the findings concerning the relatively least explored questions concerning Adolf Hitler, namely those of his youth. As the author stresses, just over a dec­ade ago Polish readers interested in the Hitler phenomenon knew much less than they do now. Thanks to several books recently published in Poland they have had a chance to considerably expand their knowledge. The present author points to two figures, Brigitte Hamann and August Kubizek, focusing on the similarities and differences in their approach to this period of Hitler’s life
Les paradoxes de Linguet
No full textBrigitte Burmeister : Linguet's paradoxes.
The social theories of Linguet (1736-1794) combine lucid criticism of 18th-century capitalism with pessimistic, even reactionary conclusions. In his Theory of Civil laws (1767), a critique of the Esprit des lois, Linguet begins with a description of the suffering caused by social inequality, to finish with a plan of reform which rejects any social change. Taking as a starting-point two " paradoxes " of Linguet — his apologies for slavery and for oriental despotism — the author demonstrates how these theories reveal the limitations of Enlightenment ideology by reflecting the contradictions of capitalistic society, insoluble within the framework of bourgeois emancipation. This results in the case of Linguet, not in a communistic Utopia but in an equally utopie, and yet reactionary, rejection of Enlightenment thought.Burmeister Brigitte. Les paradoxes de Linguet. In: Dix-huitième Siècle, n°7, 1975. pp. 147-155
Brigitte Hamann, Hitlers Edeljude: Das Leben des Armenarztes Eduard Bloch
No full textIn this extraordinary book, Brigitte Hamann recounts the life and times of Hitler’s Jewish childhood physician, Dr. Eduard Bloch (1872-1945). Relying on meticulous research in Austria, Germany, and the United States, the author provides insights into the ambiguous feelings of admiration and respect that characterized the relationship of the Jewish doctor and the Nazi dictator throughout their lives. Hamann not only sweeps away misconceptions about Hitler’s youth, but in lucid, often gripping,..
Trim17, novel E3 ubiquitin-ligase, initiates neuronal apoptosis
No full textAccumulating data indicate that the ubiquitin-proteasome system controls apoptosis by regulating the level and the function of key regulatory proteins. In this study, we identified Trim17, a member of the TRIM/RBCC protein family, as one of the critical E3 ubiquitin ligases involved in the control of neuronal apoptosis upstream of mitochondria. We show that expression of Trim17 is increased both at the mRNA and protein level in several in vitro models of transcription-dependent neuronal apoptosis. Expression of Trim17 is controlled by the PI3K/Akt/GSK3 pathway in cerebellar granule neurons (CGN). Moreover, the Trim17 protein is expressed in vivo, in apoptotic neurons that naturally die during post-natal cerebellar development. Overexpression of active Trim17 in primary CGN was sufficient to induce the intrinsic pathway of apoptosis in survival conditions. This pro-apoptotic effect was abolished in Bax(-/-) neurons and depended on the E3 activity of Trim17 conferred by its RING domain. Furthermore, knock-down of endogenous Trim17 and overexpression of dominant-negative mutants of Trim17 blocked trophic factor withdrawal-induced apoptosis both in CGN and in sympathetic neurons. Collectively, our data are the first to assign a cellular function to Trim17 by showing that its E3 activity is both necessary and sufficient for the initiation of neuronal apoptosis. Cell Death and Differentiation (2010) 17, 1928-1941; doi: 10.1038/cdd.2010.73; published online 18 June 201
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