683 research outputs found
Lily Buchwald Collection 1999
No full textThe collection contains a questionnaire filled out by Lily Buchwald regarding her life in Austria before World War II, emigration from Austria to the United States, and
life in the United States. Also included are birth certificates, school certificiates, employment certificates and letters of recommendation, marriage certificates, citizenship
certificates, emigration certificates, identity certificates, and photographs.Lily Buchwald (née Rattner) was born in Vienna 1915, the second of Hersh Ber and Ryfcia Rattner's four children. After school, she worked as a secretary at a
law office in Vienna. In 1937, she married businessman/artist Julius Buchwald. She escaped to England in June 1938. Her husband (and later her mother and sister Trude) followed in fall
1938. In 1945, Lily and Julius Buchwald emigrated to the United States. She worked as an office manager, secretary, and bookkeeper in New York until 1975. Julius Buchwald was a
specialist for chess problems (he won the Chess-Problem-World-Championships of 1946 and 1948) and was also known as a composer and artist. Lily Buchwald's sister-in-law was
author and composer Mimi Grossberg, Julius Buchwald's sister.An inventory is available in the folderAustrian Heritage Collection;Processed for digitizationSent for digitizationReturned from digitizationLinked to online manifestationdigitize
AHC interview with Trude Lowenthal and Lily Buchwald
No full textTrude Lowenthal was born Trude Rattner in Vienna, 1913. She was the oldest of Hersh Ber and Ryfcia Rattner's four children. Alltogether they lived on Neubagasse in the 7th Viennese district. After attending school, she worked as an accountant, did various office jobs at a department store and later at a store for car- and motorcycle supplies in Vienna. She left Austria for England in 1938 without her first husband, engineer Erwin Basch (who committed suicide in France 1940, when the German Army broke through). Her sister Lily Buchwald had already been in England a few months before her. She emigrated to the U.S.A. in 1949 where she later married Carl Lowenthal, who was originally from Germany. She worked as an accountant until her retirement in 1988. Trude Lowenthal lives in Jackson Heights, Queens, NY.Lily Buchwald was born Lily Rattner, in Vienna 1915 as the second-oldest of Hersh Ber and Ryfcia Rattners four children. After school, she worked as a secretary at a law office in Vienna. In 1937, she got married to the businessman/artist Julius Buchwald. After the "Anschluss", she managed to escape to England, in June 1938. Her husband (and later her mother and sister Trude) followed in fall 1938. In 1945, Lily and Julius Buchwald emigrated to the USA. She worked as an office manageress, secretary and bookkeeper in New York until 1975. Julius Buchwald (1909-1970) was a specialist for chess problems (he won the Chess-Problem-World-Championships of 1946 and 1948) and was also known as a composer and artist. Lily Buchwald's sister-in-law was author/poet/composer Mimi Grossberg (1905-1997), Julius Buchwald's sister. Lily Buchwald lives in Jackson Heights, Queens, NY.Austrian Heritage CollectionSee also Lily Buchwald Collection (AR 11120) and Trude Lowenthal Collection (AR 11121
Henri Temianka Correspondence; (buchwald)
No full textThis collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1511/thumbnail.jp
Supplementary_Tables - The Effect of Recovery Warm-up Time Following Cold Storage on the Dynamic Glucose-stimulated Insulin Secretion of Isolated Human Islets
No full textSupplementary_Tables for The Effect of Recovery Warm-up Time Following Cold Storage on the Dynamic Glucose-stimulated Insulin Secretion of Isolated Human Islets by Oscar Alcazar, Alejandro Alvarez, Camillo Ricordi, Elina Linetsky and Peter Buchwald in Cell Transplantation</p
Linear Amine-Linked Oligo-BODIPYs: Convergent Access via Buchwald-Hartwig Coupling
No full textA convergent route towards nitrogen-bridged BODIPY oligomers has been developed. The synthetic key step is a Buchwald-Hartwig cross-coupling reaction of an alpha-amino-BODIPY and the respective halide. Not only does the selective synthesis provide control of the oligomer size, but the facile preparative procedure also enables easy access to this type of dyes. Furthermore, functionalized examples were accessible via brominated derivatives
The Romance of Science: Essays in Honour of Trevor H. Levere
No full textThe Romance of Science pays tribute to the wide-ranging and highly influential work of Trevor Levere, historian of science and author of Poetry Realised in Nature, Transforming Matter, Science and the Canadian Arctic, Affinity and Matter and other significant inquiries in the history of modern science. Expanding on Levere’s many themes and interests, The Romance of Science assembles historians of science -- all influenced by Levere's work -- to explore such matters as the place and space of instruments in science, the role and meaning of science museums, poetry in nature, chemical warfare and warfare in nature, science in Canada and the Arctic, Romanticism, aesthetics and morals in natural philosophy, and the “dismal science” of economics. The Romance of Science explores the interactions between science's romantic, material, institutional and economic engagements with Nature
Structural Reevaluation of the Electrophilic Hypervalent Iodine Reagent for Trifluoromethylthiolation Supported by the Crystalline Sponge Method for X-ray Analysis
No full textHypervalent iodine λ[superscript 3]-benziodoxoles are common electrophilic transfer reagents known for their enhanced stability compared to their non-cyclic analogues. Herein we present data showing that chlorobenziodoxole reacts with two different thiolate nucleophiles (thiocyanate and trifluoromethylthiolate), resulting in the formation of stable thioperoxy complexes rather than the expected benziodoxole derivatives. We further report a revised structure for the earlier described electrophilic trifluoromethylthiolation reagent (1), which was previously believed to contain the benziodoxole framework. Our findings, which are based on a combination of analytical techniques, including the recently introduced crystalline sponge method for X-ray analysis, unambiguously demonstrate that 1 is a thioperoxy compound both in solution and the solid state.National Institutes of Health (U.S.) (Award GM58160
2,2,5,5-Tetramethyloxolane (TMO) as a Solvent for Buchwald–Hartwig Aminations
No full textBuchwald–Hartwig amination is one of the most important methods for the synthesis of N-arylamines and is widely employed for the synthesis of potential pharmaceuticals, natural products, and other fine chemicals. The reaction usually uses a Pd(0) catalyst such as Pd(dba)2 and (±)-BINAP in the presence of a base, and toluene is the most commonly used solvent. However, there are significant safety, toxicological, and environmental hazards associated with the use of toluene. Herein, we demonstrate the successful application of 2,2,5,5-tetramethyloxolane (TMO), a solvent with a similar property profile to toluene, for Buchwald–Hartwig amination reactions for coupling a wide range of primary and secondary amines with aryl bromides. When NaOt-Bu was used as the base, similar yields were obtained in toluene and TMO. In contrast, using Cs2CO3, TMO outperformed toluene significantly for electron-deficient aryl bromides that could be susceptible to nucleophilic attack. To showcase the use of TMO as a solvent for Buchwald–Hartwig aminations, the synthesis of a key intermediate in the route to smoothened (SMO) receptor antagonist drug candidate SEN826 was successfully accomplished in TMO. Improved metrics and reduction in residual palladium in the isolated amines demonstrate further benefits in the substitution of toluene with TMO in Buchwald–Hartwig aminations
Complexation Thermodynamics of Cyclodextrins in the Framework of a Molecular Size-Based Model for Nonassociative Organic Liquids That Includes a Modified Hydration-Shell Hydrogen-Bond Model for Water
No full textThe complexation thermodynamics of a large number of guest molecules with natural α-, β-, and γ-cyclodextrins (CD) can be well-described within the framework of a recently introduced, unified, molecular size-based model for nonassociative liquids that also includes a modified hydration-shell hydrogen-bond model for water (Buchwald, P.; Bodor, N. J. Am. Chem. Soc. 2000, 122, 10671). With increasing guest size, 1:1 complex stability, as measured by ln K or ΔG°, tends to increase linearly up to a size limit characteristic for each CD. For α- and β-CD, the corresponding slopes and intercepts are in excellent agreement with those predicted by the model. For larger guest structures, values level off and are scattered around an average value depending on shape, goodness of fit, and possibly lipophilicity and some specific effects (e.g., such as those caused by presence of phenol functionality). It is an important achievement in the description of interactions in liquids that the very same interaction constants derived from boiling point and enthalpy of vaporization data can describe partition, and now complex stability data as well. Furthermore, for most molecules, heat capacity changes associated with complex formation are also in excellent agreement with those derived from the model based on hydrogen bonding changes in the hydration shell
Svetlobno inducirana s paladijem katalizirana Buchwald-Hartwig aminacija
No full textThe goal of this master’s thesis was to investigate the use of light to enable the acceleration of the Buchwald-Hartwig amination of deactivated aryl chlorides with an ammonium source using a newly developed and optimized state-of-the-art catalyst system. A photoreactor was designed, modelled, and constructed to allow for a reproducible reaction setup under controlled conditions. The optimal light source and reaction conditions were investigated using a model reaction. Conversion of the starting material, product yield and potential byproducts were quantified by gas chromatography (GC) analysis and confirmed by mass spectroscopy (GC/MS). The use of light (3 W 447 nm) enabled the accelerated conversion of aryl chlorides towards the amination products even at room temperature in 2 hours, which is a remarkable improvement upon the previously reported state-of-the-art. Under optimized conditions, the highest yield (88 %) was achieved using a catalyst complex formed from β-methyl naphthyl (β-MeNAP) palladium bromide and the sterically demanding ligand AdBrettPhos. The structure of the complex crystal was elucidated using X-ray crystallography after the crystallization of the catalyst species.Cilj tega magistrskega dela je bil raziskati uporabo svetlobe za pospešitev Buchwald-Hartwigove aminizacije deaktiviranih arilkloridov z amonijevim virom z uporabo novo razvitega in optimiziranega sodobnega katalizatorskega sistema. Fotoreaktor je bil zasnovan, modeliran in izdelan, da bi omogočil ponovljivo postavitev reakcije v nadzorovanih pogojih. Optimalni vir svetlobe in reakcijski pogoji so bili raziskani z uporabo modelne reakcije. Pretvorba izhodne snovi, izkoristek produkta in morebitni stranski produkti so bili količinsko opredeljeni z analizo s plinsko kromatografijo (GC) in potrjeni z masno spektroskopijo (GC/MS). Uporaba svetlobe (3 W 447 nm) je omogočila pospešeno pretvorbo arilkloridov v produkte aminizacije tudi pri sobni temperaturi v dveh urah, kar je izjemen napredek glede na predhodno opisano stanje. Pri optimiziranih pogojih je bil največji izkoristek (88 %) dosežen z uporabo katalizatorskega kompleksa, tvorjenega iz β-metilnaftil paladijevega bromida (β-MeNAP) in sterično zahtevnega liganda AdBrettPhos. Po kristalizaciji katalizatorske vrste je bila z rentgensko kristalografijo pojasnjena struktura kompleksnega kristala
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