162,748 research outputs found

    The Levi Perryman Collection, 1873-1921

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    Record of Levi Perryman Sheriff costs for M. W. Costers vs F. C. Taylor 3.25,J.S.HaglervsJ.M.Bryant3.25, J. S. Hagler vs J. M. Bryant 4.25, A. Perryman vs R. P. Hunter 0.60,andJohnnasBarleyvsF.C.Taylor0.60,and Johnnas Barley vs F. C. Taylor 3.25. signed by F. B White

    The Levi Perryman Collection, 1873-1921

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    Received of Levi Perryman the amount of $13.00 for fees in the case of The State vs. J. Stowe

    The Levi Perryman Collection, 1873-1921

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    A promissory note from Levi Perryman to J. M. Bowers for $59.95 with an interest at 12% starting from the date it was signed. The writing on the back indicates that the money was received September 12, 1885

    The Levi Perryman Collection, 1873-1921

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    Receipt of J. M. Bowers for the sum of $9.94 due for the case of Naiddison vs A. Perryman

    The Levi Perryman Collection, 1873-1921

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    Check from Levi Perryman to T.R. Culver for eleven dollars on November 12, 1914. The Check is from The First National Bank in Saint Jo, Texas. The back of the check is endorsed by T.R Culver and J. Tillman. The stamp on the front of the check is signed November 14, 1914

    Perryman, J E, Vp7124

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/410462Surname: PERRYMAN. Given Name(s) or Initials: J E. Military Service Number or Last Known Location: VP7124. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 45490.226178 Item: [2016.0049.42731] "Perryman, J E, Vp7124

    The Relaxed Complex Method: Accommodating Receptor Flexibility for Drug Design with an Improved Scoring Scheme

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    An extension of the new computational methodology for drug design, the " relaxed complex" method (J.-H. Lin, A. L. Perryman, J. R. Schames, and J. A. McCammon, Journal of the American Chemical Society, 2002, vol. 24, pp. 5632-5633), which accommodates receptor flexibility, is described. This relaxed complex method recognizes that ligand may bind to conformations that occur only rarely in the dynamics of the receptor. We have shown that the ligand-enzyme binding modes are very sensitive to the enzyme conformations, and our approach is capable of finding the best ligand enzyme complexes. Rapid docking serves as an efficient initial filtering method to screen a myriad of docking modes to a limited set, and it is then followed by more accurate scoring with the MM/PBSA (Molecular Mechanics/Poisson Boltzmann Surface Area) approach to find the best ligand - receptor complexes. The MM/PBSA scorings consistently indicate that the calculated binding modes that are most similar to those observed in the x- ray crystallographic complexes are the ones with the lowest free energies
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