1,721,109 research outputs found
Beware of reflectance confocal microscopy artifacts when searching hyphae in acral skin
Full text linkReflectance confocal microscopy in infectious diseases
No full textIn vivo reflectance confocal microscope (RCM) is a high-resolution non-invasive imaging technique that was initially focused on the diagnosis of skin cancers. A rising number of other indications have been later described for the diagnosis and management of inflammatory and infectious dermatological disorders. RCM can identify cutaneous parasites that are not visible to naked eye such as Sarcoptes scabiei and Demodex folliculorum and it allows to better identify the different body parts of bigger parasites such as ticks. Fungal filaments can also be identified as elongated bright structures in the cutaneous upper layers. RCM cannot observe virus directly. However, the cytopathic effect associated with some virus can be recognized. In addition of being helpful for the diagnosis and follow-up after treatment, thanks to its non-invasiveness, RCM allows pathophysiological studies
In Vivo and Ex Vivo Confocal Microscopy for the Management of a Melanoma of the Eyelid Margin
No full textDiagnosis of scabies by high-magnification dermoscopy: the "delta-wing jet" appearance of Sarcoptes scabiei
No full textConfocal Microscopy for Special Sites and Special Uses
No full textThis article describes the use of confocal microscopy for special sites and unconventional applications. These new applications have been made possible thanks to the introduction on the market of a hand-held camera. Special sites discussed include mucosa, nails, and palms and soles. Special uses discussed include infections and infestations; tumor mapping; understanding clinical, dermoscopic, and histology features; videos and ex vivo confocal microscopy
On the feasibility of confocal microscopy for the diagnosis of scabies [Microscopie confocale pour le diagnostic de la gale : questions sur la faisabilité]
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Reflectance confocal microscopy for cutaneous infections and infestations
No full textReflectance confocal microscopy (RCM) is a high-resolution emerging imaging technique that allows non-invasive diagnosis of several cutaneous disorders. A systematic review of the literature on the use of RCM for the study of infections and infestations has been performed to evaluate the current use of this technique and its possible future applications in this field. RCM is particularly suitable for the identification of Sarcoptes scabies, Demodex folliculorum, Ixodes, Dermatophytes and Candida species in the clinical practice and for the follow-up after treatment. The cytopathic effect of herpes simplex virus, varicella zoster virus and molluscipoxvirus is also detectable by this imaging technique even in a pre-vesicular stage. In addition, thanks to its non-invasiveness, RCM allows pathophysiological studies
The contribution of reflectance confocal microscopy in the diagnosis of Paget's disease of the breast
No full textIn Vivo Reflectance Confocal Microscopy for Mucous Membranes
No full textReflectance confocal microscopy (RCM) is an advanced noninvasive diagnostic technique that allows tissue imaging in vivo, contributing to a more accurate diagnosis of skin cancers. Recently, the RCM devices dedicated to the skin have also been applied to perform “virtual biopsies” of the oral, genital, and ocular mucosa, sensitive areas where noninvasive imaging techniques are of high interest to spare biopsies and excisions. In this chapter, RCM features of healthy mucosa are described as well as most important features to distinguish melanosis from melanoma. Besides being useful for the diagnosis, RCM may be helpful to identify the area to be biopsied in case of large or multifocal mucosal lesions and may be regarded as a complementary technique for noninvasive assessment of treatment efficacy
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