180 research outputs found
A Brief History of Human Time - Cross-verified Dataset
No full text
This cross-verified dataset contains 2.2 million individuals, it can be used for research purposes. This dataset is linked to the following paper that should be cited directly instead of the data itself:
Morgane Laouenan, Palaash Bhargava, Jean-Benoît Eyméoud, Olivier Gergaud, Guillaume Plique, Etienne Wasmer (2022) A cross-verified database of notable people, 3500BC-2018AD, Scientific Data, June 2022.
Bibtex:
@article{bhht3,
author = {Laouenan, Morgane and Bhargava, Palaash and Eyméoud, Jean-Benoît and Gergaud, Olivier and Plique, Guillaume and Wasmer, Etienne},
title = {A cross-verified database of notable people, 3500BC-2018AD},
journal = {Scientific Data},
publisher = {Nature Publishing Group},
year = {2022},
month = {Jun},
day = {09},
volume = {9},
number = {1},
pages = {290},
issn = {2052-4463},
doi = {10.1038/s41597-022-01369-4},
url = {https://doi.org/10.1038/s41597-022-01369-4}
}
This dataset is subject to CC-BY-SA licensing.
</p
A Brief History of Human Time - Codes & Datasets
No full text
This compressed folder includes the code used for scraping and building the dataset, the intermediate datasets and the (not cross-verified) exhaustive dataset. This dataset is linked to the following paper that should be cited directly instead of the data itself:
Morgane Laouenan, Palaash Bhargava, Jean-Benoît Eyméoud, Olivier Gergaud, Guillaume Plique, Etienne Wasmer (2022) A cross-verified database of notable people, 3500BC-2018AD, Scientific Data, June 2022.
Bibtex:
@article{bhht3,
author = {Laouenan, Morgane and Bhargava, Palaash and Eyméoud, Jean-Benoît and Gergaud, Olivier and Plique, Guillaume and Wasmer, Etienne},
title = {A cross-verified database of notable people, 3500BC-2018AD},
journal = {Scientific Data},
publisher = {Nature Publishing Group},
year = {2022},
month = {Jun},
day = {09},
volume = {9},
number = {1},
pages = {290},
issn = {2052-4463},
doi = {10.1038/s41597-022-01369-4},
url = {https://doi.org/10.1038/s41597-022-01369-4}
}
The intermediate files as well as the exhaustive database are not cross-verified and should not be used directly or under the full responsibility of users.
All datasets included in this folder are subject to CC-BY-SA licensing.
</p
Tome n°1: Mouvements sociaux et écologie
No full textResponsable de la revue : Clément Reversé. Comité de lecture: Lauréna Haurat, Morgane Jouaret, Hyppolyte Koua, Mathilde Labrunie, Glenn Mainguy, Adrien Ostolski, Sarah Perrin. Comité de rédaction: Adrien Ostolski, Clément Reversé Entretien avec Razmig Keucheyan Place des ingénieurs au sein des luttes écologiques. De la critique des sciences et techniques à l'engagement politique, Antoine BOUZIN Nationalisme et écologisme autour de la construction de la centrale nucléaire ..
Pseudo-Cyprien
No full textLe jeudi 9 juin 2016, à la Maison de la recherche de Paris3, rencontre autour du traité du Pseudo-Cyprien, De duodecim abusivis saeculi, avec Clémentine Bernard-Valette, Luce Carteron, Alexis Charansonnet, Caroline Chevalier-Royet, Marie-Céline Isaïa, Morgane Leclerc, Michel Perrin, Christiane Veyrard-Cosme. Le bilan bibliographique et le diagnostic sur l'édition de référence mettent en évidence la nécessité d'une nouvelle édition et d'une étude collective sur la diffusion du traité jusqu'au ..
Réécrire "La Belle et la Bête" de Jeanne-Marie Leprince de Beaumont en littérature de jeunesse contemporaine : adaptations et réimaginations à la lumière des fonctions de personnages.
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No full textThe adult frog retina retains a reservoir of active neural stem cells that contribute to continuous eye growth throughout life. We found that Yap, a downstream effector of the Hippo pathway, is specifically expressed in these stem cells. Yap knock-down leads to an accelerated S-phase and an abnormal progression of DNA replication, a phenotype likely mediated by upregulation of c-Myc. This is associated with an increased occurrence of DNA damage and eventually p53-p21 pathway-mediated cell death. Finally, we identified PKNOX1, a transcription factor involved in the maintenance of genomic stability, as a functional and physical interactant of YAP. Altogether, we propose that YAP is required in adult retinal stem cells to regulate the temporal firing of replication origins and quality control of replicated DNA. Our data reinforce the view that specific mechanisms dedicated to S-phase control are at work in stem cells to protect them from genomic instability
Impact du bevacizumab adjuvant sur les lymphocèles dans les tumeurs épithéliales malignes de l’ovaire de stade avancé
No full textThe objective of the study was to describe the effect of adjuvant bevacizumab on symptomatic lymphoceles in advanced ovarian cancer after optimal surgery. The effect of bevacizumab on survival was also studied in this cohort. This retrospectivestudy included patients with advanced ovarian cancer (International Federation of Gynecology and Obstetrics FIGO 1988 stages IIIB, IIIC, IV) and who had cytoreductive surgery with pelvic and lombo-aortic lymphadenectomy in Gustave Roussy Institute from 2005 to 2014. 255 patients were included. The rate of symptomatic lymphocele was 33.6% (85 out of 253). 61 patients (24.5%) received adjuvant bevacizumab. In multivariate analysis, bevacizumab wasn’t associated with the risk of symptomatic lymphocele wtih hazard ratio at 1.62 (IC95%= 0.87-3.01, p=0.12). The bevacizumab had an impact on disease free survival (DFS) with hazard ratio at 0.6 (IC95%= 0.41-0.91, p=0.01) and the median DFS was 31.7 months in bevacizumab group and 23 months in the control group. In conclusion, bevacizumab wasn’t associated with the risk of symptomatic lymphocele in our study but it had an impact on DFS in patients and prolonged the median DFS by about 9 months in patients with advanced ovarian cancer and complete surgery. Further studies are needed to confirm this result.L’objectif de cette étude est d’évaluer l’impact du bevacizumab adjuvant sur la lymphocèle symptomatique chez des patientes atteintes d’un cancer de l’ovaire de stade avancé ayant eu une chirurgie complète. L’impact du bevacizumab sur la survie sera ensuite étudié chez ces mêmes patientes. Cette étude rétrospective incluait des patientes atteintes d’un cancer de l’ovaire de stades FIGO (Fédération Internationale de Gynécologie Obstétrique) 1988 IIIB, IIIC et IV ayant été opérées d’une cytoréduction complète avec curages pelviens et lombo-aortique à l’Institut Gustave Roussy entre 2005 et 2014. 255 patientes ont été incluses dans l’étude. Le taux de lymphocèle symptomatique était de 33,6% (85/253). 61 patientes ont été traitées par bevacizumab adjuvant, soit 24,5% des patientes. En analyse multivariée, le traitement par bevacizumab n’était pas significativement associé à la présence d’une lymphocèle symptomatique avec un hazard ratio (HR) à 1,62 (IC95%=0,87-3,01) p=0,12). Le bevacizumab adjuvant avait un impact significatif sur la survie sans récidive avec un HR à 0,6 (IC95%=0,41-0,91 et p=0,01) et la survie médiane sans récidive passait de 23 à 31,7 mois. En conclusion, le bevacizumab n’a pas d’impact sur la survenue de la lymphocèle postopératoire mais a un impact sur la survie sans récidive avec un gain de 8,7 mois dans cette cohorte de patientes de stade avancé et opérées d’une chirurgie complète, ce qui nécessite une confirmation par des essais thérapeutiques
Role of saturated covers as oxygen buffers in cold climates
No full text[T]his report explores a hybrid-applied solution: the use of saturated covers, which involve lifting an elevated water table into a tailing impoundment that maintains saturation within the tailing profile without allowing excess water directly along the surface of the embankment. The objective of this project is to evaluate the efficacy of saturated covers in Northern regions by testing oxygen diffusion in a series of experiments with two levels of saturation using an instrumented column. While there has been some research detailing the beneficial use of saturated covers, such as in the Oxygen diffusion in saturated covers methodology and literature review (Gagne Turcotte et al., 2020) completed prior to this lab scale study, the methodology used within this study relied heavily on prediction variables/models: De and Kr, but
these proved to be more complicated than expected (Gagne Turcotte et al., 2020). Additionally, mine tailings by nature are rather unique and each sample of tailings has its own unique characteristics that need to be accounted for. Thus, the creation of this methodology occurred, with a specific emphasis on applied methods.--from IntroductionPublication is a an outcome of the oxygen diffusion in saturated covers project
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