118,156 research outputs found
PREOPERATIVE INTRA-ORAL ULTRASOUND IN THE EVALUATION OF EARLY ORAL SQUAMOUS CELL-CARCINOMA: PROSPECTIVE STUDY
No full textPreoperative evaluation of depth of invasion can predict occult metastasis in cervical lymph nodes of OSCC patients and target patients who need neck dissection but there is no standard modality to determine this parameter preoperatively. The primary aim of this study was to evaluate the accuracy of a preoperative measurement of depth of invasion using Ultrasonography and correlate the values obtained with histologically determined DOI measurements. Specifically, we used a very small and thin Ultrasound probe, like a toothbrush, that help directly reach the oral lesions. We enrolled 32 biopsy proven primary T1/T2/T3 OSCC patients who underwent pre-operative intraoral ultrasound for the evaluation of the tumor diameter and depth of invasion. Ultrasound sensitivity, specificity and accuracy in the assessment of the infiltration of the lamina propria, the correlation between Ultrasound and histological depth of invasion and the correlation between diameter of the lesion and depth of invasion assessed with Ultrasound were evaluated. Ultrasound sensitivity and specificity in the assessment of the infiltration of the lamina propria were respectively 93.3% and 100%. A significant correlation was found between the measurement of US-obtained and histologically obtained depth of invasion (r = 0.907; p < .0001; 95% CI, 0.816 to 0.954). A medium correlation was found between diameter of the lesion and depth of invasion assessed with Ultrasound (r = 0.591; p < .0001; 95% CI, 0.306 to 0.779). According to our results, intraoral Ultrasound is very accurate in determining tumor depth of invasion in OSCC patients and represents a useful, cost-effective and promisig tool to insert in the diagnostic flow-chart of OSCC
Photo-Biomodulation as a prevention and management modality of oral mucositis in patients undergoing allogeneic hematopoietic stem cell transplantation: clinical study
No full textAim: To observe the effectiveness of a Photo-Biomodulation (PBM) protocol as a prevention and management modality for Oral Mucositis (OM) in patients undergoing conditioning regimen for allogeneic Hematopoietic Stem Cell Transplantation (aHSCT). Introduction: OM is one of the major debilitating complications of aHSCT. PBM has been recommended as a prophylactic intervention for OM in patients undergoing aHSCT. The absence of a standardized protocol and technical parameters for prevention of OM is still the principal limit. Materials and Methods: Forty-nine patients undergoing aHSCT were included in this study and divided into three groups; Observational Group (OG): 9 patients (3 females and 6 males) were subjected to PBM five sessions a week when the OM was developed till the complete resolution. Preventive Group (PG): 20 patients (7 females and 13 males) were subjected to PBM five sessions a week starting at one day before the conditioning regimen till the 10th day after transplantation (D+10). Retrospective Control Group (CG): 20 patients (10 females and 10 males) were selected to compare the obtained results. At each session, the OM score, pain value, count of blood cells, and the morphine dosage were recorded. Results: The mean duration of OM in PG (4.7 days) was significantly lower than CG (15 days) (p<0.05). Only 40% of PG showed severe OM, while it was shown in 85% of the CG (p<0.05). OM was not developed in 8 patients of the PG (with grade 0). Conclusion: The study demonstrates that the preventive PBM protocol reduced the severity and duration of OM in patients undergoing aHSCT
A combined RSA and FE study of the implanted proximal tibia: correlation of the post-operative mechanical environment with implant migration
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Orthopaedic treatment efficiency in skeletal class III malocclusions in young patients : RME-face mask versus TSME
No full textAim To cephalometrically compare the skeletal vertical and sagittal effects of TSME with those of RME protraction facemask therapy in Class III patients. Materials and methods The sample of this retrospective study included 104 patients (53 females, 51 males) with age ranging from 5 to 9 years, presenting a skeletal Class III relationship: 52 were treated with transverse sagittal maxillary expander (TSME) appliance (Group 1) and 52 with Hyrax rapid maxillary expander/facemask (RME/FM, Group 2). For each patient a lateral cephalogram was obtained before treatment (T0) and at the end of the retention period (T1). Changes in the two groups during the observation period were calculated, compared and statistically analysed with t-test. Results TSME can produce skeletal changes and dento-alveolar modifications. RME in association with protraction facemask showed that after treatment the maxilla was moved significantly forward. The correction of the ANB angle was due to a change in mandibular position during treatment which showed a backward and downward rotation. Conclusion Both devices were effective in the treatment of subjects with skeletal Class III due to maxillary retrusion
Permanence of skeletal changes following function regulator (FR-2) treatment of retrusive Class II patients
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