1,720,998 research outputs found
The orbit, including the lacrimal gland and lacrimal drainage system
No full textThis book is a comprehensive, in-depth, and up-to-date resource on eye pathology that will be of great practical value for ophthalmic and general pathologists and ophthalmologists. Congenital abnormalities, inflammatory conditions, infections, injuries, degenerative diseases, and tumors are all covered with the aid of more than 700 images. In the case of tumors, the wide variety of neoplasms that occur in the eyelid, conjunctiva, retina, uveal tract, lacrimal gland and sac, orbit, and optic nerve are comprehensively reviewed, and the most recent knowledge on the relation between genetics and prognosis is presented. Entries on specific diseases are organized in a standard way, with information on etiology, epidemiology, clinical presentation, pathological characteristics, differential diagnosis, therapy, and prognosis. The authors are all recognized experts and members of the European and American ophthalmic pathology societies.
Anatomia patologica del glaucoma
No full textAnatomia funzionale e patologica dell'angolo camerulare dell'occhio e sua relazione con il glaucom
Physiological mechanisms preventing plant wilting under heat stress: a case study on a wheat (Triticum durum Desf.) bound water-mutant
No full textWilting is the main symptom of plants suffering the dehydration stresses, but the mechanisms governing this phenomenon are yet to be completely understood. In this work, a holistic analysis of physiological traits potentially involved in leaf wilting was performed, comparing a wheat wild type (WT), Trinakria and its water-mutant (WM) with a “high affinity for bound water (BW)”. In addition to the tendency to wilt, significant differences between genotypes were observed for leaf temperature achieved under heat stress, leaf turgor loss with decreasing water potential, cuticular transpiration, and Q10 of leaf water uptake velocity. We hypothesize that mutant plants prevent the increase in leaf temperature thanks to the rapid and low energetic cost of water diffusion from the vessels to the outside, driven by the BW. Under strong thermal-induced dehydration stress, BW delays leaf wilting through its positive effects on cell wall elasticity and passive osmoregulation
Effects of culling on vigilance behaviour and endogenous stress response of female fallow deer
Get PDFContext Human activities can induce behavioural and stress responses in wild animals. Information is scarce on the effects of culling on anti-predator behaviour and endogenous stress response of wild ungulates. Aims In a Mediterranean area, we evaluated the effects of culling on vigilance, foraging and endogenous stress response of female fallow deer (Dama dama). Methods Effects of culling were evaluated through behavioural observations and hormone analyses of faecal samples. Key results In an area where culling occurred (C), individuals showed significantly greater vigilance rates and foraged closer to wood than in an area with no culling (NC). In C, 24h after culling, faecal cortisol concentrations were greater than those recorded in NC, but they decreased significantly to values comparable to (48h post-shot) and lower than (72h post-shot) those observed in NC. Conclusions Most likely, culling determined behavioural responses in female fallow deer, but did not trigger long-term physiological effects. Implications Increased anti-predator behaviour may complicate the implementation of long-term culling programs
An evaluation of 605 endoscopic examination in a rural setting, Lacor Hospital in Northern Uganda
Full text linkIntroduction: The aim of this study was to evaluate the profile of esophagogastroduodenal
(EGDS) diseases diagnosed by upper endoscopy in a rural area of Uganda in a retro-protective
study of 605 patients.
Results: The mean age of patients with digestive symptoms was 39.7yrs (SD +/-16.11) and female
gender predominated by 60% compared to the male (P value 0.000). Peasant farmers were the
commonest group with GI symptoms requiring EGDS compared to the rest 72.1% v 27.9%.
Epigastric pain was the commonest indication (58%) for EGDS, followed by chest pain (11%),
abdominal pain (8.8%), dyspahgia (7.6%) and hematemesis (7.3%). The commonest endoscopy
finding was gastritis (47.9%) followed by esophagitis (14.4%), cancer esophagus (5.1%),
esophageal varicose (4%), PUD (2.3%), gastric cancer (1%). However 19.5% of patients had
normal EGDS. There was a significant correlation between the outpatient diagnosis and
endoscopy finding (P value 0.01, r = 0.144) and between endoscopy finding and histology findings
(P value 0.001, r = 0.236). H. pylori was positive in 53% of patients with gastritis.
Conclusion: Gastritis is the commonest lesion (47.9%) of which 53% have H pylori and Cance
Verrucous Carcinoma of the Uterine Cervix Arising in a Giant Condyloma Acuminatum, Associated with Ichthyosis of the Endometrial Cavity
Full text linkWe describe a unique presentation of a cervical verrucous carcinoma (VC) associated with ichthyosis of the uterine cavity in
an 80-year old woman. Areas of transition from a giant condyloma (GC) were present in the VC. This paper also includes a review of the relevant
literature. VC of the cervix is an uncommon malignancy, and transition of a GC to VC is an interesting finding, confuting the theory
that they represent distinct entities, with different risk factors. Differently from GC, VC is considered to be causally related to HPV in a minority
of instances. Our results of p16 immunohistochemistry, the surrogate marker of high-risk human papillomavirus (HPV) infection, appear
to speak against the causal role of HPV in the pathogenesis of VC. Ichthyosis uteri may occasionally be associated with a cervical or
endometrial malignancy; however, we are not aware of any patient showing VC, GC and ichthyosis uteri at the same time
Barriers and factors affecting personal protective equipment usage in St. Mary’s Hospital Lacor in Northern Uganda
Full text linkBackground: To protect health workers (HCWs) from risky occupation exposure, CDC developed the universal precautions (Ups) including Personal Protective Equipment (PPEs). However compliance to it by HCWs has remained poor even in high-risk clinical situation. The objective of this study was to identify and describe the factors that influence a HCWs’ decision to wear PPEs and the barriers that exist in preventing their use
Methods: A cross-sectional survey was carried out in the St. Mary’s Hospital Lacor in all the wards to collected quantitative information as well as qualitative and observational data on PPE use
Results: Out of the total 59 respondents, 2% do not know the purpose of PPE, 23.7% do not know how to don and doff PPEs, 13.6% do not use PPE even when indicated and 10% are not using an appropriate PPE. The main barriers relates to poor fitting and weak domestic gloves, few of aprons, frequent stock out and inadequate PPE as well as lack of training in PPE
Conclusion: This study provides a baseline for measuring the effectiveness of interventions to improve compliance
Case report: biloma gastrostomy after failed sonogram-guided percutaneous aspiration, pigtail catheter insertion and surgical drainage
Full text linkBilomas are rare abnormal extrabiliary accumulation of bile. This can be either
intrahepatic or extrahepatic following traumatic or spontaneous rupture of the
biliary tree. The commonest causes of biloma are surgery, percutaneous
transhepatic cholangiography, percutaneous transhepatic biliary drainage,
transcatheter arterial embolization and abdominal trauma. We report here a 15
year old patient whom we followed for over 10 years. His chief complaints were
right hypochondriac pain, loss of appetite and vomiting. Initial clinical
presentation, sonographic as well as laboratory findings suggested a liver
abscess, which was drained, but the definitive diagnosis of biloma was
entertained after sonographically guided percutaneous aspirations and
percutaneous transhepatic cholangiography 7 years later. We also discuss the
role of imaging and surgical challenges encountered that culminated into
bilomo-gastrostomy. The patient is now enjoying a peaceful life
A 10 years trend of peptic ulcer disease and other gastrointestinal disorders in Northern Uganda
Full text linkBackground: The changing trend of GI disorders has not been expounded in our setting,
there is need to examine the extent to which major endoscopically diagnosed upper GI
disorders have changed in the last 10 years (2005 to 2015).
Methods: This was a retrospective study in which endoscopically diagnosed GI disorders of
Jan-Jun 2005 were compared with 2015 (10 years) for the same period
Results: In the 10 years (2005 to 2015), the prevalence of peptic ulcer disease (PUD)
reduced from 9.6% to 2.9% (P value 0.000), followed by esophageal varices from 10.3% to
4.0%, and duodenitis from 3.2% to 0.7% respectively. Gastritis increased from 18.4% to
48.2% (P value 0.000), followed by cancer esophagus from 3.2% to 5.1%.
Conclusion: As the prevalence of PUD decreases in our community, gastritis increases hence
patients with upper GI symptoms tend to suffer gastritis thus clinicians should focus on
treating gastritis and eradication of Helicobacter pylor
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