899 research outputs found

    Pawankar, Ruby

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    Allergic rhinitis: Current options and future perspectives

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    PURPOSE OF REVIEW: Allergic rhinitis due its high prevalence and burden needs to be properly treated. The disease's clinical features impose well tolerated drugs usable for long-term treatment. Nowadays, second-generation antihistamines and inhaled steroids represent the milestone of rhinitis therapy. The aim of the present review is to provide an update on allergic rhinitis treatment. A particular attention has been deserved to clinical trials, published in the last year that assess the efficacy and safety of new formulation of available drugs or new molecules. RECENT FINDINGS: Available and new drugs under investigation seem able to control rhinitis symptoms without a significant patient's burden. The challenge for the next years will be to improve treatment adherence rather than to introduce new drugs. SUMMARY: Allergic Rhinitis and its Impact on Asthma guidelines have brought attention to allergic rhinitis and its impact on asthma, but have also proposed a new classification in terms of symptoms severity and persistence useful for tailoring treatment on patients' phenotypes. Their further dissemination is needed; furthermore, they represent a cornerstone for the scientific community through a continuous update on relevant issues such as rhinitis phenotypes, disease management on the basis of new treatments, clinical trials transferability in real life, and allergic rhinitis management in public health programs. © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins

    Letter From Ruby Doris Smith to her Mother, circa 1964

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    Correspondence from Ruby Doris Smith to her mother about being in Conakry, Guinea in West Africa. 4 pages

    Rhinitis: adherence to treatment and new technologies

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    Purpose of review Nonadherence to treatment is a major issue in approximately 50% of patients suffering from chronic diseases. The availability of new technologies could represent a possible way to improve patients' engagement and adherence in a real-life setting. Research and technology tools made available or in process of being made available to patients with allergic diseases and their physicians could potentially improve the management of these disease in daily life by improving adherence. In this review, we sought to outline many of the recent advances in these technological approaches. Recent findings Short Message Service (SMS) reminder, social networks, wearable devices, mobile applications (Apps), monitoring systems of inhaled device use, often presented as 'serious game' are changing the way of approaching to chronic disease, such as rhinitis, management. Summary Studies of the role played by various technologies in improving adherence to treatment in rhinitis are still limited as compared with other diseases such as asthma, but the results are encouraging. Further studies in this area may lead to the discovery of novel management approaches that is easy to be integrated in patients' daily life

    Letter to Mother From Ruby D. Smith, June 21, 1961

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    Letter from Ruby Doris Smith in Hinds County Jail, Jackson, Mississippi, to her mother. Smith was in jail for taking part in the Freedom Rides. 1 page

    [Prisoner medical records describing the condition of Jack Ruby]

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    Partially illegible prisoner medical records by an unknown author, on photocopied index cards. The records describe the condition of Jack Ruby upon his arrest

    Adherence to asthma treatments: we know, we intend, we advocate

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    PURPOSE OF THE REVIEW: To highlight the state of the art and the current outlook on the adherence to treatment in asthma, starting from the ‘Manifesto on Adherence to asthma treatment in respiratory allergy’ endorsed by the World Allergy Organization, Allergic Rhinitis and Its Impact on Asthma and Global Allergy, Asthma European Network, and Interasma.RECENT FINDINGS: Adherence to the pharmacological treatments of asthma is known to be low: about 50% of those who had been prescribed long-term treatment are nonadherent, at least part of the time. Nonadherence is associated with lack of asthma control, poor health outcomes, and increased costs. The reasons for suboptimal adherence are multifaceted and may be related to the patients, the treatment and asthma features, the physician–patient relationship, and the healthcare resources and facilities.SUMMARY: Taking into account the multidimensional nature of adherence, no single intervention or strategy is per se able to enhance it, but all players involved in the process (government authorities, patient organizations, scientific societies, stakeholders, and others) are called to work together to develop a combined action plan based on the patientʼs complexity

    [Prisoner medical records describing the condition of Jack Ruby]

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    Partially illegible prisoner medical records by an unknown author, on photocopied index cards. The records describe the condition of Jack Ruby upon his arrest and a letter requesting examination by the Dallas Police Department and the Federal Bureau of Investigation

    [Prisoner medical records describing the condition of Jack Ruby]

    No full text
    Partially illegible prisoner medical records by an unknown author, on photocopied index cards. The records describe the condition of Jack Ruby upon his arrest
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