1,527 research outputs found
Senior Recital by Roderick Ferland, alto saxophone, May 14, 1964
No full textThis is the concert program of the Senior Recital by Roderick Ferland, alto saxophone on Thursday, May 14, 1964 at 8:30 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Scherzo by J. Casterede, Histoires by Jacques Ibert, Rapsodie pour Saxophone Alto, Op. 92 by Pierre Vellones, Concerto pour Saxophone Alto et Trompette by Jean Rivier, and Sonata, Op. 19 by Paul Creston. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund
Assessing the impact of chronic kidney disease on individuals and populations: use of relative and absolute measures
No full textChronic kidney disease (CKD) is now recognized as a global public health problem, contributing substantially to the burden of non-communicable disease (NCD) [1, 2]. CKD is associated with a variety of NCD outcomes, including renal [end-stage renal disease (ESRD)], cardiovascular and non-cardiovascular. It is important to quantify the risks associated with CKD on such disease outcomes in individuals and the impact of CKD on whole populations, and given the high prevalence of CKD and increased risks of most NCDs at older ages, how the impact of CKD varies by age. The paper by Marks et al. is a population-based study using routinely collected data in the Grampian region of Scotland which aimed to determine the effect of CKD (largely Stage 3b–5) on renal replacement therapy (RRT) and all-cause mortality (ACM). The impact of CKD on RRT and ACM was mainly due to CKD in older age groups, a paradox given that the absolute risk of progression to RRT in the CKD cohort and the relative risks of ACM associated with CKD both fell with age. The findings are firstly an illustration of the contrasting information provided by relative and absolute measures of the effects of risk factors, age and CKD on disease outcomes, and secondly highlight the possible interaction between age and CKD. The authors also developed risk prediction tools to determine the absolute risk of RRT and ACM for patients with CKD. This article considers these concepts in more detail<br/
Recent Decisions
No full textComments on recent decisions by William J. Gerardo, Thomas M. Clusserath, Roderick A. Mette, John J. Coffey, Paul J. Schierl, Gerald M. Gallivan, Lawrence James Bradley, and Thomas A. McNish
Recent Decisions
No full textComments on recent decisions by William J. Gerardo, Thomas M. Clusserath, Roderick A. Mette, John J. Coffey, Paul J. Schierl, Gerald M. Gallivan, Lawrence James Bradley, and Thomas A. McNish
Recent Decisions
No full textComments on recent decisions by William J. Gerardo, Thomas M. Clusserath, Roderick A. Mette, John J. Coffey, Paul J. Schierl, Gerald M. Gallivan, Lawrence James Bradley, and Thomas A. McNish
Estimating kidney function in adults using formulae
No full textWith increasing emphasis on the earlier detection and management of chronic kidney disease (CKD), estimation of the glomerular filtration rate (GFR) has assumed greater importance. It is accepted that use of serum creatinine concentration alone as a marker of kidney function is inadequate; in particular, it has a poor sensitivity for detecting CKD. International recommendations favour the reporting of creatinine-based estimates of GFR using formulae which also take into account age, gender and other variables that affect the relationship between serum creatinine and GFR: in particular, the four-variable formula derived from the Modification of Diet in Renal Disease study (4-v MDRD) is increasingly being used. We have reviewed the literature supporting the use of this formula compared with the well-established Cockcroft and Gault formula. Overall, evidence supports the use of the 4-v MDRD formula as an improved estimate of GFR in people with moderate/advanced CKD. Neither formula performs well in people with normal and mildly reduced kidney function. However, there remain significant problems with this approach and areas where further research is required. In particular, the widespread adoption of estimated GFR reporting has refocused attention on the limitations of creatinine measurement and highlighted clinical situations in which the formulae are inadequate
A revised phylogenetic classification of tribe Phyllantheae (Phyllanthaceae)
No full textBouman, Roderick W., Kebler, Paul J.A., Telford, Ian R.H., Bruhl, Jeremy J., Strijk, Joeri S., Saunders, Richard M.K., Esser, Hans-Joachim, Falcón-Hidalgo, Banessa, Van, Peter C. (2022): A revised phylogenetic classification of tribe Phyllantheae (Phyllanthaceae). Phytotaxa 540 (1): 1-100, DOI: 10.11646/phytotaxa.540.1.
Can health technologies be assessed using routine data?
No full textObjectives: The potential of routine data for health technology assessment (HTA) in the United Kingdom was assessed.Methods: Compiled were a comprehensive list of routine databases, their classification according to data characteristics, literature review on their current use, and their comparison with key topics identified as priorities for HTA.Results: Two hundred seventy health-care databases for England or the English regions were identified. Twenty-four included data on both health technology and patient health state. Eleven found some published use in effectiveness evaluation. Of 140 prioritized health technologies, only 22 could be identified in routine databases.Conclusions: Routine data are plentiful but of limited use in HTA. The data sets usually do not include the effect of treatments. Coding is inadequate, and confidentiality regulations will make matters worse. Both need urgent attention
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