6,043 research outputs found

    W. Warde Fowler, Rome

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    Petit Paul. W. Warde Fowler, Rome. In: L'antiquité classique, Tome 37, fasc. 1, 1968. pp. 349-350

    W. Warde Fowler, Rome

    No full text
    Petit Paul. W. Warde Fowler, Rome. In: L'antiquité classique, Tome 37, fasc. 1, 1968. pp. 349-350

    UoM-maul1609/bin-diffusion-model: Full working version

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    <p>Bin Diffusion Model is a bin microphysics parcel model to solve for the condensational growth of liquid aerosol particles into cloud droplets. It also calculates the homogeneous nucleation of water ice in both aqueous solution droplets and cloud drops. The model treats each liquid size bin in a novel way, treating the diffusion of water through each liquid droplet. It can therefore answer questions about the importance of ultra viscous aerosol on cloud formation processes. </p> <p>This version of the code enables the calculation of homogeneous nucleation of a distribution of aerosol particles with each bin, solving a separate radially symmetric Fickian diffusion equation. Diffusion coefficients can either be constant or can be calculated according to published values that depend on water mole fraction. Output is to a NetCDF file, which must be read and plotted with the user's own program (see GitHub wiki page for an example).</p> <p>See Fowler et al (2019) for details:</p> <p><a href="https://doi.org/10.5194/acp-2019-401">https://doi.org/10.5194/acp-2019-401</a></p>Natural Environment Research Council (NERC) EAO Doctoral Training Partnership under grant reference number NE/L002469/1 Natural Environment Research Council (NERC) "The effects of organic material on warm and cold cloud formation: from the laboratory to regional and global impacts" under grant reference number NE/L007827/

    Elements of Abstraction: Space, Line and Interval in Modern British Art

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    The book is the catalogue of the exhibition Elements of Abstraction: Space, Line and Interval in Modern British Art, which the author curated from the collections of the Tate Gallery, London, the Arts Council, London, Southampton City Art Gallery and private collections. The author provided three essays, 'The Geometry of Modern British Art', 'West Country Constructivism', and 'Abstract Art and the Decline of Modernism' to advance critical histories of three distinct moments of importance in the development of British abstract art. A fourth, edited by him, was by a research student under his supervision (Alan Fowler) and covered Systems Art and Constructionism

    Senior Recital: Paul Fowler, voice

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    Junior Recital: Paul Fowler, voice

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    Fowler Block

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    Photograph - Fowler Block, Athabasca, Alberta. The building was built in the early 1950s by G.G. Fowle

    Maxwell-Stefan diffusion: a framework for predicting condensed phase diffusion and phase separation in atmospheric aerosol (Supporting code)

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    <p>This repository contains code to accompany the paper "Maxwell–Stefan diffusion: a framework for predicting condensed phase diffusion and phase separation in atmospheric aerosol" by Fowler et al. (2018).</p> <p>https://www.atmos-chem-phys.net/18/1629/2018/acp-18-1629-2018.html</p>This work was funded by the Natural Environment Research Council (NERC) through the PhD studentship of Kathryn Fowler under the grant reference number NE/L002469/1. Paul J. Connolly acknowledges funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement number 603445 EU FP7

    Senior Recital: Paul K. Fowler, composition

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    The acid tolerance response of enteropathogenic Salmonella and Escherichia coli strains : A proteomic characterisation and novel links with motility and virulence

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    This thesis concentrates on elucidating the mechanisms involved in the adaptation of exponentially growing EPEC and Salmonellai to inorganic and weak organic acids. An understanding of these mechanisms, collectively known as the acid tolerance response (ATR) is of relevance to both the food production and medicinal industries.One of the most striking findings is that flagellin, the major structural component of the bacterial flagellum, is down-regulated at pH 3.0 in acid adapted Salmonella. Further studies using reporter gene fusions indicate that the entire flagellar apparatus is transcriptionally repressed under these conditions. PhoPQ is found to mediate this mechanism, which results in a loss of cell motility, by acting directly or indirectly at the level of the flagellar fhCD master operon.One of the most striking findings is that flagellin, the major structural component of the bacterial flagellum, is down-regulated at pH 3.0 in acid adapted Salmonella. Further studies using reporter gene fusions indicate that the entire flagellar apparatus is transcriptionally repressed under these conditions. PhoPQ is found to mediate this mechanism, which results in a loss of cell motility, by acting directly or indirectly at the level of the flagellar flhCD master operon.Additional links between other virulence associated mechanisms and the ATR are also investigated. 2 ATR proteins regulated by PhoPQ are expressed similarly during the oxidative stress response. Correspondingly, survival assays indicate that an acid induced cross protection of oxidative stress in Salmonella is mediated by this global regulator. A further two regulators of pathogenesis (the BipA GTPase and the EAF plasmid) are characterised as negative regulators of the ATR in certain EPEC strains. It is concluded that ATR mechanisms are variable between different species and strains.Based on these results, it is proposed that intimate connections exist between the regulation of the ATR and virulence associated processes, such as motility, that are essential for pathogenesis. The full elucidation of the mechanisms behind the regulation and implementation of these systems may pave the way for future treatments of food-borne disease. The global regulatory molecules involved constitute putative drug targets.</p
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