628 research outputs found
Portrait of Elizabeth Salter, author [picture] .
No full textTitle from inscription on reverse.; Condition: Fair.; Inscriptions: "Elizabeth Salter, author" --In pencil on reverse. "15 Oct 1951" --Stamped on reverse
Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1? in chondrocyte/agarose constructs
No full textIntroduction: The present study examined the effect of C-type natriuretic peptide (CNP) on the anabolic and catabolic activities in chondrocyte/agarose constructs subjected to dynamic compression. Methods: Constructs were cultured under free-swelling conditions or subjected to dynamic compression with low (0.1 to 100 pM) or high concentrations (1 to 1,000 nM) of CNP, interleukin-1? (IL-1?), and/or KT-5823 (inhibits cyclic GMP-dependent protein kinase II (PKGII)). Anabolic and catabolic activities were assessed as follows: nitric oxide (NO) and prostaglandin E2 (PGE2) release, and [3H]-thymidine and 35SO4 incorporation were quantified by using biochemical assays. Gene expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), aggrecan, and collagen type II were assessed with real-time quantitative PCR (qPCR). Two-way ANOVA and the post hoc Bonferroni-corrected t tests were used to examine data. Results: CNP reduced NO and PGE2 release and partially restored [3H]-thymidine and 35SO4 incorporation in constructs cultured with IL-1?. The response was dependent on the concentration of CNP, such that 100 pM increased [3H]-thymidine incorporation (P < 0.001). This is in contrast to 35SO4 incorporation, which was enhanced with 100 or 1000 nM CNP in the presence and absence of IL-1? (P < 0.001). Stimulation by both dynamic compression and CNP and/or the PKGII inhibitor further reduced NO and PGE2 release and restored [3H]-thymidine and 35SO4 incorporation. In the presence and absence of IL-1?, the magnitude of stimulation for [3H]-thymidine and 35SO4 incorporation by dynamic compression was dependent on the concentration of CNP and the response was inhibited with the PKGII inhibitor. In addition, stimulation by CNP and/or dynamic compression reduced IL-1?-induced iNOS and COX-2 expression and restored aggrecan and collagen type II expression. The catabolic response was not further influenced with the PKGII inhibitor in IL-1?-treated constructs. Conclusions: Treatment with CNP and dynamic compression increased anabolic activities and blocked catabolic effects induced by IL-1?. The anabolic response was PKGII mediated and raises important questions about the molecular mechanisms of CNP with mechanical signals in cartilage. Therapeutic agents like CNP could be administered in conjunction with controlled exercise therapy to slow the OA disease progression and to repair damaged cartilage. The findings from this research provide the potential for developing novel agents to slow the pathophysiologic mechanisms and to treat OA in the young and old. <br/
[Review of] John R. Salter. Jackson Mississippi
No full textJackson Mississippi is a fascinating book written about the Civil Rights Movement in Jackson, Mississippi in the sixties. The author, John Salter, a white outsider and sociologist who served as advisor and organizer of the Civil Rights Movement in Jackson is to be commended for his ability to write about the movement in such a vivid and moving manner. Salter does an excellent job in describing the many problems encountered in striking out against the many injustices that existed in Mississippi
Multi-element Polychromatic 2-dimensional Liquid Crystal Dammann Gratings
No full textThis is the underlying data from the publication: Zimo Zhao, Bohan Chen, Patrick S. Salter, Martin J. Booth, Dominic O’Brien, Steve J. Elston, and Stephen M. Morris, "Multi-element Polychromatic 2-dimensional Liquid Crystal Dammann Gratings
Dataset: Laser writing of individual nitrogen-vacancy defects in diamond with near-unity yield
No full textThis archive contains the underlying data used in the preparation of the manuscript: YC Chen et al, "Laser writing of individual nitrogen-vacancy defects in diamond with near-unity yield" Optica 6 (5), 662-667 (2019). There is photoluminessence data from a confocal microscope taken to analyse the orientation, positioning accuracy and number of nitrogen vacancy defects written in three different arrays inside diamond. There is also included the photoluminessence feedback signal recorded when laser writing each of the defects. Matlab and Origin are required to open some of the files
UCF Faculty Author Series: Academic Publishing
No full textPlease join us as UCF faculty members Anastasia Salter (School of Visual Arts and Design), Blake Scott (Writing & Rhetoric), and Keri Watson (School of Visual Arts and Design) discuss their approaches to successful writing and publishing in an academic environment. The panelists will share their most recent publications and writing experiences, which will be followed by a Q&A session. Light refreshments will be provided
Beyond Adaptation: Decolonizing Approaches to Coping With Oppression
No full textHow should one respond to racial oppression? Conventional prescriptions of mainstream social psychological science emphasize the idea of coping with oppression—whether via emotional management strategies that emphasize denial or disengagement; problem-focused strategies that emphasize compensation, self-efficacy, or skills training; or collective strategies that emphasize emotional support—in ways that promote adaptation to, rather than transformation of, oppressive social structures. Following a brief review of the literature on coping with racism and oppression, we present an alternative model rooted in perspectives of liberation psychology (Martín-Baró, 1994). This decolonial approach emphasizes critical consciousness (rather than cultivated ignorance) of racial oppression, a focus on de-ideologization (rather than legitimation) of status quo realities, and illumination of models of identification conducive to collective action. Whereas the standard approach to coping with oppression may ultimately both reinforce and reproduce systems of domination, we propose a decolonial approach to racism perception as a more effective strategy for enduring prosperity and well-being
Season 7 Episode 15: Authentic Race Relations
No full textChrist\u27s cross gave us the route to repaired relationships with God and with each other. Why do we hear so little emphasis on the horizontal peace? Calvin College January Series guest Brenda Salter McNeil, co-author of The Heart of Racial Justice: How Soul Change leads to Social Change, tells host Shirley Hoogstra what can happen when we recognize the spiritual roots of our segregation, shed the false roles we\u27ve taken on, and speak the truth. Episode #715
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