26 research outputs found
Petrus Alfonsi and his Dialogus. Background, Context, Reception
No full textPetrus Alfonsi’s Dialogus (ca. 1109) is a fictitious disputation between Petrus, who represents the author as a Christian convert, and Moyses his former Jewish self. For the first time non-biblical Jewish literature is presented in some detail to a Latin audience and the religious practices of Muslims are discussed. Petrus bases his claim for the superiority of Christianity on its rationality and compatibility with scientific learning, for which he draws upon elements of Arabic natural philosophy.
Many aspects of this text are still poorly understood. The essays in this volume try to shed new light on Petrus’s intellectual background and on the cultural and political context in which the Dialogus was written. One group of articles studies the scarce biographical information we possess about the author, like his possible connections to Anselm of Canterbury’s school or to Adelard of Bath, another one focuses on the treatment Islam receives as a possible conversion alternative for the author, while a third group of contributions studies the work’s reception: variations of the text in its numerous manuscripts, its use as a source in later works of religious polemics and its literary influence on later authors
[CODE] CGATOxford/UMI-tools: 1.1.5
No full textNew features Enables read suffixes to be removed from single end data: @IanSudbery in https://github.com/CGATOxford/UMI-tools/pull/591. See https://github.com/CGATOxford/UMI-tools/issues/580 for motivating issue Adds a script to prepare umi_tools dedup output for use with RSEM: @IanSudbery in https://github.com/CGATOxford/UMI-tools/pull/609. See https://github.com/CGATOxford/UMI-tools/issues/465 and https://github.com/CGATOxford/UMI-tools/issues/607 for motivating issues Bugfix Fix lack of help messages in 1.1.4 by @IanSudbery in https://github.com/CGATOxford/UMI-tools/pull/586 Fixes read suffix line end: @IanSudbery in https://github.com/CGATOxford/UMI-tools/pull/611 Documentation Fixed docs for dedup stats filenames: @msto in https://github.com/CGATOxford/UMI-tools/pull/604 New Contributors @msto made their first contribution in https://github.com/CGATOxford/UMI-tools/pull/604 Full Changelog: https://github.com/CGATOxford/UMI-tools/compare/1.1.4...1.1.5Tom Smith, Ian Sudbery, Chang Y, Michael Jackson, Peter Chovanec, Jesse Bloom, jz314, redst4r, rajivnarayan, Kohl Kinning, cui jie, Bo Han, akmorrow13, Yu Fu, Matt Stone, Johannes Köster, Jan Oppelt, James Oguya, Patrick Roelli, … Andreas Heger. (2024). CGATOxford/UMI-tools: 1.1.5 (1.1.5). Zenodo. https://doi.org/10.5281/zenodo.1065732
Je rêvais aussi en quelque sorte comme la forêt
No full textDans cet entretien inédit, l’anthropologue Eduardo Kohn, auteur de Comment pensent les forêts, revient sur le rôle que le rêve a joué dans l’élaboration de ce qu’il a appelé « l’anthropologie au-delà de l’humain » et du projet qu’il mène actuellement sur le psychédélisme. Il y aborde notamment la place qu’ont tenue les rêves – les siens et ceux de ses hôtes – dans son enquête de terrain, dans son enseignement universitaire et dans ses réflexions éthiques et politiques.In this previously unpublished interview, the anthropologist Eduardo Kohn, author of How Forests Think, looks back at the role that dreams have played in the development of what he has called “the anthropology beyond the human” and his current project on psychedelics. In particular, he discusses the role that dreams―his own and those of his hosts―have played in his fieldwork, in his university teaching, and in his ethical and political reflections
Asketische Schriften des Mönchs Markos (s. XIII): Einleitung, Erstedition und Übersetzung eines Florilegiums und dreier Sermones
No full textDiese Edition präsentiert asketische Schriften des 13. Jhs., verfaßt von einem Mönch namens Markos (wahrscheinlich im Jahre 1266 niedergeschrieben). Über den Autor ist fast nichts bekannt. Eventuell stammt auch eine Auslegung des Typikons des hl. Sabas von ihm; in diesem Falle wäre er Hieromonachos (Priestermönch) gewesen. Er schuf zwei monastisch-asketische Florilegien zur Erbauung der Prinzessin Eirene Eulogia Palaiologina, der Schwester des byzantinischen Kaisers Michael VIII. Palaiologos. Das erste ist sehr umfangreich und harrt weiterhin seiner Erforschung, das zweite, das hier ediert ist, hat eine gewisse Verbreitung gefunden, wie der Bestand von drei Handschriften belegt. In der Haupthandschrift folgen im Anschluß an die Florilegien drei kurze eigene asketische Schriften des Markos sowie ein Widmungsbrief an Eirene, die hier ebenso zum ersten Mal ediert sind. Den Editionen sind die zitierten Väterstellen, eine Übersetzung und einzelne Stellenkommentare beigegeben. Markos’ Anliegen ist, seiner Leserin und schließlich auch einem weiteren Publikum die traditionelle Sicht des vollkommenen christlichen Lebens mitzuteilen – er konzentriert sich dabei v.a. auf das Gebet und das Fasten. Markos ist überzeugt, daß die Grundsätze des christlichen Lebens ebenso für Mönche wie für Laien gelten, so ist sein zweiter Traktat ist an einen Laien gerichtet. Diese Überzeugung ist typisch für die hesychastische Bewegung des 14. Jh., trotzdem finden sich in den Texten des Markos aber noch keine Hinweise zu jenen körperlichen Gebetstechniken, die im 14. Jh. zum “Hesychasmusstreit” geführt haben.
This edition presents ascetic texts from the 13th c. by a monk Mark (probably written down in the year 1266). This author is virtually unknown; possibly he also authored a commentary to the Typikon of St. Sabas, in this case he would have been hieromonachos (priest-monk). He wrote two anthologies on monastic-ascetic topics for the edification of Irene Eulogia Palaeologina, the sister of emperor Michael VIII Palaeologus. One of them is very voluminous and remains unstudied, the other has found some readers (it is contained in three manuscripts) and is here edited and studied. The main manuscript includes at its end three short ascetic treatises by Mark and a dedicatory letter for Irene, all theses texts are here also edited for the first time. The edition is accompanied by the quoted loci from the fathers, a German translation and some comments. Mark’s goal is to teach his pupil, and ultimately also other readers, the traditional view of the perfect Christian life – with a main focus on prayer and fasting. As Mark is convinced that the same principles hold good for both monastics and laymen, he consequently teaches a layman in his second sermon. Such a conviction is typical for the hesychast movement in the 14th c., nonetheless, Mark does not reveal in his opus any acquaintance with physical hesychast prayer techniques that were to cause the great debate on hesychasm in the 14th c
Teichlab/scg_lib_structs: Release 26th Oct 2023
No full text<p>This is the first release to get a DOI so that people can cite the repo.</p>
Teichlab/scg_lib_structs: Release 8th Mar 2024
No full text<p>The data folder has been completely re-organised to make things cleaner. This may break some historical links from other websites.</p>
Hoohm/CITE-seq-Count: 1.4.2
No full textSmall script that allows to count TAGS from a CITE-seq experimen
The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases
No full textThe SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to turn the exponentially growing amount of data into knowledge. Here, we provide an overview of SIB's resources and competence areas, with a strong focus on curated databases and SIB's most popular and widely used resources. In particular, SIB's Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development
No full textBlocking pyrimidine de novo synthesis by inhibiting dihydroorotate dehydrogenase is used to treat autoimmunity and prevent expansion of rapidly dividing cell populations including activated T cells. Here we show memory T cell precursors are resistant to pyrimidine starvation. Although the treatment effectively blocked effector T cells, the number, function and transcriptional profile of memory T cells and their precursors were unaffected. This effect occurred in a narrow time window in the early T cell expansion phase when developing effector, but not memory precursor, T cells are vulnerable to pyrimidine starvation. This vulnerability stems from a higher proliferative rate of early effector T cells as well as lower pyrimidine synthesis capacity when compared with memory precursors. This differential sensitivity is a drug-targetable checkpoint that efficiently diminishes effector T cells without affecting the memory compartment. This cell fate checkpoint might therefore lead to new methods to safely manipulate effector T cell responses
