2 research outputs found
Knowledge, attitude and perception of tuberculosis management among tuberculosis-infected patients in resource constraint setting: field experience from Oyo state, South-West, Nigeria
No full textBackground: Inadequate knowledge and misconceptions about tuberculosis (TB) contribute to the burden of the disease by influencing patients’ behavior and attitude towards the disease and undermining infection control efforts. This study assesses the level of knowledge, attitude and perception of TB and its management among TB-infected patients.Methods: A descriptive cross-sectional was used to interview 712 TB patients using a semi-structured questionnaire between June and October 2016. Bivariate and multivariate analyses were performed with SPSS version 20.Results: About 70% had a good knowledge of TB. Patients’ perception of stigma was high (37.5%). A high proportion of the patients had a poor perception of their illness (88%). Healthcare workers attitude was rated as satisfactory by 97.2% of respondents. Patients who had good knowledge about TB experienced high self-stigma (42%) compared to those who had poor knowledge (27.2%), p<0.05. Poor knowledge of TB was highest among relapse TB cases. Respondents with poor TB knowledge were less likely to be male (OR: 0.66; 95% CI: 0.46, 0.95), married (OR: 0.24; 95% CI: 0.10, 0.55; p=0.001) and have tertiary education (OR: 0.06; CI: 0.37, 0.87; p=0.010). Patients with good knowledge about HIV and in the richest wealth status were 91% less likely to have high perceived stigma (OR: 0.09, 95%CI: 0.02, 0.35; p=0.001).Conclusions: The level of knowledge of TB among patients is satisfactory, however perception of illness is poor. Tuberculosis diagnosis can create self-stigma because of the fear of being isolated and discriminated which may determine the success of treatment.</jats:p
Factors Associated with Mortality among Patients on TB Treatment in the Southern Region of Zimbabwe, 2013.
No full textBackground. In 2013, the tuberculosis (TB) mortality rate was highest in southern Zimbabwe at 16%. We therefore sought to determine factors associated with mortality among registered TB patients in this region. Methodology. This was a retrospective record review of registered patients receiving anti-TB treatment in 2013. Results. Of 1,971 registered TB patients, 1,653 (84%) were new cases compared with 314 (16%) retreatment cases. There were 1,538 (78%) TB/human immunodeficiency virus (HIV) coinfected patients, of whom 1,399 (91%) were on antiretroviral therapy (ART) with median pre-ART CD4 count of 133 cells/uL (IQR, 46-282). Overall, 428 (22%) TB patients died. Factors associated with increased mortality included being ≥65 years old [adjusted relative risk (ARR) = 2.48 (95% CI 1.35-4.55)], a retreatment TB case [ARR = 1.34 (95% CI, 1.10-1.63)], and being HIV-positive [ARR = 1.87 (95% CI, 1.44-2.42)] whilst ART initiation was protective [ARR = 0.25 (95% CI, 0.22-0.29)]. Cumulative mortality rates were 10%, 14%, and 21% at one, two, and six months, respectively, after starting TB treatment. Conclusion. There was high mortality especially in the first two months of anti-TB treatment, with risk factors being recurrent TB and being HIV-infected, despite a high uptake of ART
