1,909 research outputs found

    Vocabulario Portuguez & Latino, Antico ... : Tomo VIII

    No full text
    Contén ademáis: Diccionario Castellano y Portuguez para facilitar ... la noticia de la lengua Latina ... Author el P. D. Raphael Blutea

    The seated female nude : from Raphael to Ingres

    No full text
    This article discusses the history and interpretation of the painted female nude from the 15th to the 19th century. The author discusses artists from the Renaissance, such as Raphael up to Impressionism and Neoclassicism by Ingres.peer-reviewe

    Methods and tools for mining the transcriptomic landscape of human tissue and disease

    No full text
    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from PDF version of thesis.Includes bibliographical references (p. 343-356).Although there are a variety of high-throughput technologies used to perform biological experiments, DNA microarrays have become a standard tool in the modern biologist's arsenal. Microarray experiments provide measurements of thousands of genes simultaneously, and offer a snapshot view of transcriptomic activity. With the rapid growth of public availability of transcriptomic data, there is increasing recognition that large sets of such data can be mined to better understand disease states and mechanisms. Unfortunately, several challenges arise when attempting to perform such large-scale analyses. For instance, public repositories to which the data is being submitted to were designed around the simple task of storage rather than that of data mining. As such, the seemingly simple task of obtaining all data relating to a particular disease becomes an arduous task. Furthermore, prior gene expression analyses, both large and small, have been dichotomous in nature, in which phenotypes are compared using clearly defined controls. Such approaches may require arbitrary decisions about what are considered "normal" phenotypes, and what each phenotype should be compared to. Addressing these issues, we introduce methods for creating a large curated gene expression database geared towards data mining, and explore methods for efficiently expanding this database using active learning. Leveraging our curated expression database, we adopt a holistic approach in which we characterize phenotypes in the context of a myriad of tissues and diseases. We introduce scalable methods that associate expression patterns to phenotypes in order to assign phenotype labels to new expression samples and to select phenotypically meaningful gene signatures. By using a nonparametric statistical approach, we identify signatures that are more precise than those from existing approaches and accurately reveal biological processes that are hidden in case vs. control studies. We conclude the work by exploring the applicability of the heterogeneous expression database in analyzing clinical drugs for the purpose of drug repurposing.by Patrick Raphael Schmid.Ph.D

    Preservice Teachers' Development of Effective Approaches to Text-based Discussion

    No full text
    Text-based discussion is a dialogic instructional practice to promote reading comprehension among students. To enact this practice, a teacher engages students in authentic conversation about text as students read it, to assist them in building understanding of text ideas as they are encountered. Text-based discussion has the potential to promote the development of both low-level and high-level comprehension skills among students, yet teachers need support in learning to enact it. Research has indicated that text-based discussion is not well-represented in classrooms today, likely because not many teachers have access to this support. Recently, some teacher educators have focused on teaching preservice teachers (PSTs) to enact text-based discussions during teacher preparation programs, in an attempt to increase the presence of the practice in classrooms. Practice-based methods courses have been developed which attempt to provide preservice teachers with the knowledge and skill needed to enact text-based discussions successfully. This study investigated the ways in which six preservice teachers’ enactments of text-based discussion developed over the course of their one-year student teaching placements, after completing one such methods course in which they learned to enact the practice. Data were collected at three time points during student teaching, and included transcripts of enactments of text-based discussion, lesson plans, interview transcripts, and assessments of lesson quality using the Instructional Quality Instrument (Junker et al., 2004). Analysis of the data suggested that the PSTs entered student teaching with the ability to enact text-based discussions with a moderate level of success, and that the quality of the discussions continued to improve over the course of the school year. The methods course seemed to support PSTs in learning to link student comments and press students for accuracy and reasoning. PSTs were more successful in eliciting student linking and recall of explicit text information than in eliciting elaborated responses from students; the participation structure enforced by the PST seemed to influence the extent to which students provided elaborated responses. This study supports the use of practice-based methods courses to teach PSTs to enact text-based discussions, and uncovers several areas that are in need of additional focus during these courses

    High-Temperature Reactor Fuel Technology in the European Projects HTR-F1 and RAPHAEL

    No full text
    In April 2005, a new 4-year Integrated Project on Very High Temperature Reactors (RAPHAEL: ReActor for Process Heat And ELectricity) was started as part of EURATOM’s 6th Framework Programme. The Sub-Project on Fuel Technology (SP-FT) is one of eight sub-projects in RAPHAEL, with 8 partners from industry, R&D organizations and a nuclear-safety expertise organization: CEA, FZ Jülich, JRC, Nexia Solutions, AREVA-NP, NRG, Belgonucléaire and IRSN. While the earlier HTR-F and HTR-F1 projects aimed at re-mastering fuel fabrication technology, testing existing state-of-the-art HTR fuels at high burn-up and high temperature and understanding fuel behavior), the R&D conducted in RAPHAEL SP-FT focuses on understanding fuel behavior and determining the limits of state-of-the-art fuel as well as on potential further Fabrication processes will be developed for an alternative kernel composition (UCO), with a potential for decreasing the CO pressure built-up in the particle, and for an alternative coating layer (ZrC), which remains more stable at higher temperature than SiC, thus providing increased Post-irradiation examinations and heat-up tests performed on irradiated fuel will allow investigation of the behavior of state-of-the-art fuel in a VHTR’s normal and accidental conditions. Based on the fuel particle models established in FP5, the fuel modeling capabilities will be improved: An irradiation will be performed in the HFR Petten for measuring the changes in coating material properties as a function of fluence and temperature, with samples coming from the new fabrication process. This will allow introduction of particle behavior models for coatings which are not only more accurate than those presently based on old data, but also more relevant to present materials. Fission-product release modeling and statistical methods will be developed to integrate the individual behavior of thousands of particles within fuel elements. Code benchmarking, started in FP5, will be continued with the acquisition of new experimental data. This paper presents progress in RAPHAEL SP-FT as well as the remaining activities of the earlier HTR-F1 project.JRC.F.3 - High Flux and Future Reactor

    Cabala, Spiegel der Kunst und Natur in Alchymia : was der Weisen uralte Stein doch für ein Ding sey, der da dreyfach und nur ein Stein ist : welches allem müheseligen Liebhabern der Kunst zu Ehren mit Hülff Gottes, so klar als ein Spiegel fürgestelt : davon vil bisshero geschrieben aber wenigen bekand : gantz offenbar mit kurtzen Worten der gantzen Warheit durch dise beyligende Figuren erklärt vnd an Tag gegeben /

    No full text
    Plate 1 has legend: Raphael Custodis scalpsit, Stephan Michelspacher ex.First published 1616; cf. Hogart.The t.p. may imply that the author, otherwise anonymous, is represented by the coat of arms in plate 1. However, the dedication to Johann Remmelin (1583-1632) is signed "Stephan Michelspacher aus Tiroll," and the Brit. Mus. catalog has Michelspacher as author.Hogart, R. Alchemy,Mode of access: Internet.Plates in Library's copy bound in the order 2, 1, 4, 3

    Teaching Revolution: Teachers and Nationalism in Patrick McCabe's 'The Dead School'

    No full text
    This paper will explore Patrick McCabe's representation of the school teacher in The Dead School (1995). The narrative revolves around two teachers in 1970s Ireland, Raphael Bell (a headmaster), and Malachy Dudgeon (a young teacher). Bell represents a traditional conceptualisation of Irishness, strongly Catholic and nationalist, whilst Dudgeon represents a new form of Irishness, suburban and adrift, hi the inevitable collision of morals and values between the two, McCabe explores the metamorphosis of Irish identity from traditional nationalism to contemporary postnationalism. In doing so, he explores how the school teacher has long served as a symbol of nationalism in Ireland, and how the education system functioned as an institution for the perpetuation of cultural and social stasis. In The Dead School, McCabe presents a version of Ireland in which both the traditional teacher and school are under ideological threat. In Ireland, the association of nationalism with education has had a long history that reached its apogee with Padraig Pearse, leader of the 1916 Easter Rebellion. In 1908 Pearse opened St. Enda's school in Dublin with the intention of teaching Irish children in both English and Irish, and fostering a love of Irish culture in his pupils. Since then, generations of Irish children have sat in classrooms beneath photographs of Pearse and his proclamation of an independent Irish Republic in 1916. Ultimately, this paper will argue that such traditional nationalism has become anachronistic for most Irish people, and that McCabe's novel presents, in the forms of Raphael Bell and Malachy Dudgeon, a fictional representation of the ideological overthrow of Irish nationalism by a more cosmopolitan and youthful state

    Death before dismount? : mechanization, force employment, and counterinsurgency outcomes in Iraq

    No full text
    Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Political Science, 2011.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 100-105).Recent research suggests that heavily mechanized armies perform worse in counterinsurgency campaigns than those that use fewer vehicles. The U.S. military's 2007 operations in Iraq, however, present an empirical quandary for the mechanization hypothesis: a vehicle-heavy army proved able to suppress an insurgency, allowing Iraqi leaders to work towards a long-term political solution. This paper argues that force employment, not mechanization, drives counterinsurgency outcomes-what matters is not that armies have many vehicles or soldiers, but how they choose to use them. When heavily mechanized forces change their tactics and doctrine to line up with counterinsurgency principles, shifting from an enemy-centric to a population-centric approach, outcomes dramatically improve while military-wide mechanization levels remain constant. Using an original dataset, this paper conducts a large-n regression analysis of the impacts of mechanization at the provincial level in Iraq, and finds little support for the mechanization hypothesis. A subsequent comparative case study, of the heavily mechanized 3rd Armored Cavalry Regiment's operations in Tall Afar and the light infantry 82nd Airborne Division's operations in Fallujah, indicate that force employment rather than mechanization is a key indicator of counterinsurgency outcomes. The finding has important implications for force structure policy, as it indicates that mechanized forces can indeed conduct successful counterinsurgency campaigns.by Raphael E. Moyer.S.M
    corecore