2,977 research outputs found

    Patrick Hays Folder

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    41 page of family history documents containing and related to Patrick "Pat" Hays; Silvia Paananen Hays; Pearl Parsons Hays; Dr. Susan Bruder Kerr - including: Oral history; obit; index; written histor

    'If I should die tonight' poem

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    Humorous poem copied by Harrison Kerr and written by Benjamin Franklin King ca. 1890. The poem, titled "If I should die tonight," jokes about money owed to the author and the shock he would experience at being repaid upon his death. It was written as a parody of a serious contemporary poem of the same title. Harrison Henry Kerr (1839-1901), born in North Georgetown, Ohio, served along with his brother, Ezra, as a private in Company D of the 58th Ohio Volunteer Infantry. He was taken prisoner at the Battle of Chickasaw Bayou, Mississippi, on December 29, 1862., and held for three months before being exchanged and returning to his regiment. He was discharged on January 14, 1865. Following the war, he was married to Elizabeth (Rettig) Kerr. The two lived in Cleveland and had one son, Harrison McKinley Kerr. In 1888, he joined the Memorial Post No. 141, Grand Army of the Republic. He is buried in North Georgetown Cemetery

    [An artist's impression of the revised Sir John Kerr statue atop Canberra's new Parliament House] [picture] /

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    Part of the collection: Matilda collection.; Drawing signed by artist.; Matilda Gallery caption "Fraser knocks Kerr off."; Published in: "Mischief for idle hands", David McNaughton. Matilda. Canberra : Dynwest, no. 8, Nov. 1985, p. 15.Matilda (Canberra, A.C.T.

    Experimental validation of nonlinear Fourier transform-based Kerr-nonlinearity identification over a 1600km SSMF link

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    Recently, a nonlinear Fourier transform-based Kerr-nonlinearity identification algorithm was demonstrated for a 1000 km NZDSF link with accuracy of 75%. Here, we demonstrate an accuracy of 99% over 1600 km SSMF. Reasons for improved accuracy are discussed.Accepted Author ManuscriptTeam Sander Wahl

    International Harmonization and the Gains from Trade

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    International harmonization of standards and regulations is often a goal expressed in trade agreements because it is expected to yield gains from trade. Absence of progress toward harmonization is often interpreted as being motivated by protectionism, with differences in standards and regulations seen as non-tariff barriers. While protectionism may well be the source of resistance to harmonization, there may be other reasons it is not pursued. These alternative explanations have not received much attention from economists. In this article some of these alternatives are outlined - demand effects from altering standards, switching costs, proprietary technologies. The article concludes that proposals for international harmonization need to be scrutinized carefully.demand effects, harmonization, regulation, standards, switching costs, TBT, International Relations/Trade,

    The regulation of PARP proteins by the m⁶A methyltransferase machinery

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    RNA methylation is an important regulator of RNA metabolism. The most common form of internal mRNA methylation is N6-methyladenosine (m⁶A), which is deposited by the m6A methyltransferase complex (MTC). This occurs co-transcriptionally, meaning the MTC must interact with components within the broader chromatin environment, in order to rapidly and selectively access nascent RNA. My thesis is a step towards a better understanding of those interactions. In the first part of my thesis, I examine the cellular response to UV-C irradiation, which has recently been demonstrated to induce dynamic m6A deposition. Not only do I find limited evidence to support this model, I also show this discrepancy partly arises from the cross-reactivity of m6A antibodies with poly (ADP-ribose) (PAR), which confounds imaging data. I then identify a previously uncharacterised regulatory relationship between the core MTC protein, METTL3, and the synthesis of PAR (PARylation). In the second part of the thesis, I utilise a range of experimental techniques in an attempt to describe how PARylation is affected by the loss of METTL3. These experiments give no single answer, but indicate several contexts in which PARylation and METTL3 may be linked. In the third section, I present a study of how PARP-1 and PARylation is regulated by METTL3 during the exit from pluripotency, and in the context of MEK/ERK signalling. At the heart of this section is a proteomic dataset that measures changes to the PARP-1 chromatin-associated interactome, in the presence and absence of METTL3. This identifies several interesting candidate proteins, on which further research can be based. In summary, I have identified, and begun the characterisation of, a regulatory relationship between two important processes: the m⁶A modification of RNA and PARylation. This may have important consequences for understanding several aspects of cell homeostasis and disease

    Magnetised Kerr/CFT correspondence

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    AbstractThe tools of Kerr/CFT correspondence are applied to the Kerr black hole embedded in an axial external magnetic field. Its extremal near horizon geometry remains a warped and twisted product of AdS2×S2. The central charge of the Virasoro algebra, generating the asymptotic symmetries of the near horizon geometry, is found. It is used to reproduce, via the Cardy formula, the Bekenstein–Hawking entropy of the magnetised Kerr black hole as the statistical microscopic entropy of a dual CFT. The presence of the background magnetic field makes available also a second dual CFT picture, based on the U(1) electromagnetic symmetry, instead of the only rotational one of the standard non-magnetised Kerr spacetime.A Meissner-like effect, where at extremality the external magnetic field is expelled out of the black hole, allows us to infer the value of the mass for these magnetised extremal black holes.The generalisation to the CFT dual for the magnetised extreme Kerr–Newman black hole is also presented

    Does the spirit of Charles Dickens live on in his furniture?

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    A table owned by the author has been export stopped in the UK – a situation that Dickens himself would have relishe

    Recession, International Trade and the Fallacies of Composition

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    A truly global recession has not been manifest since the Great Depression of the 1930s. As a result, the multilateral institutions put in place at the end of the Second World War to ensure that a major depression never happened again have not been tested. One of the lessons of the Great Depression was that governments had a major role to play in managing the economy. The use of subsidies to affect economic outcomes was one manifestation of this expanded role. In a recession, sector specific subsidies will likely be requested by firms. Subsidies can distort trade, leading to the potential for beggar thy neighbour subsidy wars. Subsidies will be difficult to discipline in a global recession.beggar thy neighbour, deficits, paradox of thrift, recession, subsidies, International Relations/Trade,
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