256 research outputs found
METHOD DEVELOPMENT AND VALIDATION FOR RELATED SUBSTANCES OF BOSUTINIB MONOHYDRATE BY RP-HPLC METHOD
Yogendra B. Parmar*, Dharmesh Shah, Yashraj A. Majmudar, Ketul C. Kaka, Arpan S. Patel, Pankaj D. Kankad and Uday G. Sartanpar
Are the days of closed pleural biopsy over? Yes
In the modern management of pleural diseases, thoracoscopy has a clear advantage over closed pleural biopsy. By way of its high yield, both in malignant pleural disease and pleural Tuberculosis – the two commonest cause of undiagnosed pleural effusion, thoracoscopy has the added advantage of faster symptom relief and offering effective pleurodesis. This makes it an attractive diagnostic and therapeutic procedure of choice and features high in the algorithms of many international guidelines on the approach to pleural diseases
UA12/2/1 Graduation Guide
Special graduation edition of the College Heights Herald: Ransdell, Gary. Letter to Class of 2015 Taylor, Nicki. Letter to Class of 2015 – Student Government Association Rogers, Shelby. College Heights Herald News Editor Havel, Catherine. Spirit Masters Patel, Dharmesh. International Student Diplomat Beal, Josh. Talisma
Bioactive Components from Dietary Sources
This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Evaluation of anti-ulcer activity of pectic polysaccharide extract of Zingiber officinale and Brassica oleracea in different animal models
This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Poly-3-hexylthiophene Nanorods as A Donor for Organic Photovoltaics
Poly-3-hexylthiophene functionalized silsesquioxane nanorods (P3HT-NRs) were prepared by direct hydrolysis and condensation of P3HT-silane precursor using the modified Stöber method. The silane precursor was stirred in a mixture of two solvents in the presence of a base under room temperature for three different reaction times. The size, shape, and morphology of these novel nanostructures were visualized using the transmission electron microscope (TEM) and scanning electron microscope (SEM). The composition of the P3HT-NRs was confirmed by FTIR and its silane by proton NMR. Future work will focus on evaluating photovoltaic performance of these nanorods as a donor for organic photovoltaics
A Novel Fibre Composite System to Investigate Tenocyte Metabolism Under Physiological and Pathological Loading Conditions.
PhDTendons are crucial for locomotion, transferring forces from muscle to bone. They are subjected to high forces, and possess highly specialised hierarchical structures to function efficiently. Tendinopathies are debilitating tendon disorders common in both athletes and non-athletes. The unclear aetiology of tendinopathies has led to limited, generalised treatment, with poor regenerative outcomes for patients. Tendinopathies are thought to be instigated by changes in the local cellular environment, with tendon overuse generating matrix microdamage, which increases cellular shear. Shear is potentially an important mechanotransduction cue, but no mechanism is available to investigate this directly.
To address this need, a fibre composite system based on polyethylene glycol (PEG) was developed, consisting of cell seeded PEG-peptide fibres encapsulated in a PEG matrix. Composites were developed to mimic the cell mechanical environment in tendons, creating shear-tension ratios equivalent to those seen physiologically (40% of applied strain transferred to the fibres; the remaining 60% as fibre shearing within the matrix). High shear-low tension (~25% tension, ~75% shear) and low shear-high tension (~60% tension, ~40% shear) environments were also developed to investigate non-physiological conditions.
Broad spectrum gene expression analysis was performed to determine how different shear-tension ratios affect the behaviour of tenocytes derived from healthy and tendinopathic human tendons. Tendinopathic tenocytes appeared more mechano-sensitive than healthy tenocytes (shear-tension mediated changes in versican, IL-8, TIMP-3, MMP-3 and MMP-13 expression) and showed a distinct basal profile similar to that observed in tendinopathic tissue (lower MMP-3 and higher MMP-13 expression). Further investigation with bovine tenocytes found changing the cell attachment peptide in fibres from RGD to DGEA increased the sensitivity of tenocytes to the local shear-tension environment (shear-mediated changes in scleraxis, MMP-2 and COL-3 expression). This suggests tenocytes are more responsive when attached to collagen-like materials, and consequently that specific integrins are involved in sensing the local shear-tension environment.Arthritis Research U
Bioactive Compounds From Dietary Sources- Comparitive Evaluation
This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Patterns and practices of contemporary software entrepreneurs
Thesis (S.M.M.O.T.)--Massachusetts Institute of Technology, Sloan School of Management, Management of Technology Program, 2006.Includes bibliographical references (leaves 106-109)."When you write a book, you need to have more than an interesting story. You need to have a desire to tell the story. You need to be personally invested in some way. You need to care about it." Malcolm Gladwell Author, "The Tipping Point". "I have never thought of writing for reputation and honor. What I have in my heart must come out, that is the reason why I compose. " Ludwig van Beethoven. The above quotes answer the basic question that many people have asked me (and I have asked myself): Why are you writing a thesis? The answer is simple: I believe there's a story to be told, and I have a personal passion for the subject. This thesis will analyze the patterns and practices of contemporary software startups. Though much has been written about software companies and much has been written on startups, I'm primarily interested in the intersection: software startups. More specifically, I will explore contemporary software startups that were started after the Internet bubble burst. About The Website: onstartups.comAs part of the thesis writing experience, I started a blog called "OnStartups" (http://onstartups.com) where I have been posting articles on software startups. More information on the onstartups.com site is included at the end of the thesis. My passion for learning more about software startups, the opportunity to work with two exceptional individuals as co-advisors and the overwhelming response to my onstartups.com website are my primary motivations for this thesis. Onward!by Dharmesh Shah.S.M.M.O.T
Health Beneficial Components From Dietary Sources.
This Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
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