580 research outputs found
A hierarchical spectral clustering and nonlinear dimensionality reduction scheme for detection of prostate cancer from magnetic resonance spectroscopy (MRS)
No full textIn this article the authors present a novel CAD scheme that integrates nonlinear dimensionality reduction (NLDR) with an unsupervised hierarchical clustering algorithm to automatically identify suspicious regions on the prostate using MRS and hence avoids the need to explicitly identify metabolite peaks.The published version of this article is available at: http://scitation.aip.org/getpdf/servlet/GetPDFServlet?filetype=pdf&id=MPHYA6000036000009003927000001&idtype=cvips&prog=normalThis work was made possible via grants from the Wallace H. Coulter Foundation, New Jersey Commission on Cancer Research, National Cancer Institute (Grant Nos. R01CA136535-01, ARRA-NCl-3 R21CA127186–02S1, R21CA127186–01, and R03CA128081-01), the Society for Imaging Informatics in Medicine (SIIM), The Cancer Institute of New Jersey, and the Life Science Commercialization Award from Rutgers University
Digital pathology image analysis: opportunities and challenges
No full textThe published version of this article is available at: http://www.futuremedicine.com/doi/pdf/10.2217/iim.09.
The role of carbon dioxide as an orientation cue for western corn rootworm larvae within the maize root system: implications for an attract‐and‐kill approach
No full textBACKGROUNDWestern corn rootworm larvae use CO2 to locate maize roots. However, the importance of CO2 as a specific orientation cue close to maize roots has not been investigated unequivocally. This study aimed at elucidating the effect of CO2-emitting capsules in combination with a soil insecticide (Tefluthrin=attract and kill) within the root system. We hypothesized that the capsules would result in aggregation of the larvae at the soil insecticide, thus increasing its efficacy. A nondestructive observation device was used to study larval distribution and behaviour. RESULTSSpatial analysis of distance indices (SADIE) revealed aggregation of the larvae around the capsules in an attract-and-kill treatment after 4h, which was not found with the conventional treatment without the capsules. However, larval mortality did not differ between treatments. CONCLUSIONCO2 is a weak attractant for western corn rootworm larvae within the root system. Consequently, an attract-and-kill strategy based on a CO2 product will not contribute to better control compared with conventional Tefluthrin applications. Host-specific compounds, combined with a CO2 source, should be used to target more larvae, making attract and kill a feasible management option against this pest. (c) 2013 Society of Chemical IndustryGerman Environmental Foundation (DBU
Evaluation of new fermentation and formulation strategies for a high endophytic establishment of Beauveria bassiana in oilseed rape plants
No full textSince several years it is known that strains of the entomopathogenic fungus Beauveria bassiana (Balsamo-Crivelli) Vuillemin (Ascomycota: Hypocreales) are able to colonize plants as a true endophyte. However, so far no integrated bioprocess engineering approaches have been published where fermentation and formulation strategies are combined to optimize colonization of oilseed rape plant tissues. We therefore aimed at investigating whether and how blastospore (BS) formation can be shifted to resilient submerged conidiospores (SCS) by introducing osmotic stress in different growth phases. When 50 g/L NaCl was added after 48 h to a culture of B. bassiana a yield of 1.4 +/- 0.1 x 10(10) SCS/g sucrose in shake flasks and 1.8 +/- 0.1 x 10(10) SCS/g sucrose in a stirred tank reactor were obtained. In a bioreactor, 24 h after the addition of NaCl, the formation of BS slowed down, the respiratory quotient decreased and a shift from BS to SCS set in. Following these steps, different formulation strategies, namely encapsulation, film coating and liquid formulation were evaluated. B. bassiana grew out of beads as well as on commercial fungicide-coated seeds. Due to the complete suppression of fungal growth on non-sterile soil, the most suitable option was a foliar application. A liquid formulation consisting of 0.1% Triton X-114, 1% molasses, 1% titanium dioxide and 10(6) spores/mL was applied on leaf tips. After 14 days, the endophyte was detected by PCR and microscopic analysis in the leaves. Further research should focus on formation of SCS and protection of plants colonized by B. bassiana against herbivorous insects. (C) 2015 Elsevier Inc. All rights reserved.German Federal Ministry of Education and Research [FKZ 17N1510
Formulations for novel biological pest control strategies
No full textPatel A. Formulations for novel biological pest control strategies. ZEITSCHRIFT FUER NATURFORSCHUNG SECTION C. 2017;72(9-10):E6
Development of a Self‐Adhesive Oleogel Formulation Designed for the Slow Release of Semiochemicals
No full textDeutsche Forschungsgemeinschaft https://doi.org/10.13039/50110000165
Technical scale production of encapsulated <i>Saccharomyces cerevisiae</i> and <i>Metarhizium brunneum</i> attractive to wireworms
No full textDevelopment of an attract-and-kill co-formulation containing<i>Saccharomyces cerevisiae</i>and neem extract attractive towards wireworms
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