1,721,300 research outputs found
Effectiveness of resin-coated gutta-percha cones and a dual-cured, hydrophilic methacrylate resin-based sealer in obturating root canals.
No full textThe introduction of a polybutadiene-diisocyanate-methacylate resin-coating of gutta-percha enables the polyisoprene to be chemically coupled to methacrylate-based resin root canal sealers. This study examined the effectiveness of using passively fitting cones of this type of gutta-percha with a dual-cured version of EncloREZ sealer in obturating cleaned and shaped root canals. The hydrophilic nature of the sealer enabled the creation of an extensive network of 800 to 1200 mu m long sealer resin tags after removal of the encloclontic smear layer. Although no adhesive was employed, thin hybrid layers in root dentin were observed when EDTA was used as the final rinse, Nevertheless, interfacial gaps and silver leakage could be,observed along the sealer-dentin interfaces that might be attributed predominantly to polymerization shrinkage of the sealer. Gaps and silver leakage were also identified between the gutta-percha resin-coating and the sealer
Collagen degradation by host-derived enzymes during aging.
No full textIncompletely infiltrated collagen fibrils in acid-etched dentin are susceptible to degradation. We hypothesize that degradation can occur in the absence of bacteria. Partially demineralized collagen matrices (DCMs) prepared from human dentin were stored in artificial saliva. Control specimens were stored in artificial saliva containing proteolytic enzyme inhibitors, or pure mineral oil. We retrieved them at 24 hrs, 90 and 250 days to examine the extent of degradation of DCM. In the 24-hour experimental and 90- and 250-day control specimens, we observed 5- to 6-microm-thick layers of DCM containing banded collagen fibrils. DCMs were almost completely destroyed in the 250-day experimental specimens, but not when incubated with enzyme inhibitors or mineral oil. Functional enzyme analysis of dentin powder revealed low levels of collagenolytic activity that was inhibited by protease inhibitors or 0.2% chlorhexidine. We hypothesize that collagen degradation occurred over time, via host-derived matrix metalloproteinases that are released slowly over time
Potential iatrogenic tetracycline staining of endodontically treated teeth via NaOCl/MTAD irrigation – a preliminary report.
No full textThis study reported red-purple staining of light-exposed, root-treated dentin when root canals were rinsed with 1.3% NaOCl as initial rinse followed by the use of BioPure MTAD as final rinse. This intrinsic dentin staining occurred irrespective of whether the root canals were filled, and could be observed even in crown dentin when the latter was sequentially immersed in NaOCl and MTAD. Bench-top reproductions of the phenomenon revealed that the exothermic reaction is not an acid-base reaction. Conversely, the reaction is of a redox nature that highly resembled the previously reported mechanism of tetracycline staining, in which photo-oxidation of tetracycline resulted in a red-purple tetracycline degradation product that has a high affinity for hydroxyapatite. This photo-oxidative degradation process is probably triggered by the use of NaOCl as an oxidizing agent, and may be prevented by rinsing the NaOCl-treated dentin with ascorbic acid, a reducing agent, before the application of MTAD
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