1,244 research outputs found
AN UPDATE ON SECESSION AS THE "ULTIMATE RIGHT": FOR A LIMINAL LEGALITY
No full textLIMINAL LEGALITY AS A NEW FORM OF LEGALITY FOR SECESSION IN INTERNATIONAL LAW. THE AUTHOR PROPOSE A NEW LEGAL THEORY OF SECESSION
How should context-escaping closures proceed?
No full textContext-oriented programming treats execution context explicitly and provides means for context-dependent adaptation at runtime. This is achieved, for example, using dynamic layer activation and contextual dispatch, where the context consists of a layer environment of a stack of active layers. Layers can adapt existing behaviour using proceed to access earlier activated layers. A problem arises when a call to proceed is made from within a closure that escapes the layer environment in which it was defined. It is not clear how to interpret proceed when the closure is subsequently applied in a different environment, because the layers it implicitly refers to (such as the original layer and/or the remaining layers) may no longer be active. In this paper, we describe this problem in detail and present some approaches for dealing with it, though ultimately we leave the question open.status: Publishe
Generic accelerated sequence alignment in SeqAn using vectorization and multi-threading
No full textMotivation
Pairwise sequence alignment is undoubtedly a central tool in many bioinformatics analyses. In this paper, we present a generically accelerated module for pairwise sequence lignments applicable for a broad range of applications. In our module, we unified the standard dynamic programming kernel used for pairwise sequence alignments and extended it with a generalized inter-sequence vectorization layout, such that many alignments can be computed simultaneously by exploiting SIMD (Single Instruction Multiple Data) instructions of modern processors. We then extended the module by adding two layers of thread-level parallelization, where we a) distribute many independent alignments on multiple threads and b) inherently parallelize a single alignment computation using a work stealing approach producing a dynamic wavefront progressing along the minor diagonal.
Results
We evaluated our alignment vectorization and parallelization on different processors, including the newest Intel® Xeon® (Skylake) and Intel® Xeon Phi™ (KNL) processors, and use cases. The instruction set AVX512-BW (Byte and Word), available on Skylake processors, can genuinely improve the performance of vectorized alignments. We could run single alignments 1600 times faster on the Xeon Phi™ and 1400 times faster on the Xeon® than executing them with our previous sequential alignment module.
Availability
The module is programmed in C++ using the SeqAn (Reinert et al., 2017) library and distributed with version 2.4. under the BSD license. We support SSE4, AVX2, AVX512 instructions and included UME::SIMD, a SIMD-instruction wrapper library, to extend our module for further instruction sets. We thoroughly test all alignment components with all major C++ compilers on various platforms
Portrait of Costanza Bonarelli and the Two Biographies of Bernini
No full textP(論文)It is well known that the biography of Bernini written by Filippo Baldinucci and another by his son, Domenico Bernini, are the most important sources for studies on Bernini. In recent years, the interests in these two biographies have grown tremendously and scholars have carefully studied them from various angles. Domenico's biography of Bernini translated to English by Franco Mormando, and the collection of critical essays
on Bernini's biographies edited by Maarten Delbeke and others, are the most significant results of these studies.
In this essay, the author discusses characteristics of the two biographies, centered around Portrait of Costanza Bonarelli. First, the author translates the notable documents concerning the scandal of Bernini and Costanza Bonarelli into Japanese, and sums the historical facts. Then the author introduces Costanza’s early life and her whereabouts after the scandal, based on the study published by Sarah McPhee on Costanza Bonarelli.
Taking into consideration of all the historical facts and descriptions of the scandal by Baldinucci and Domenico, the author discusses intentions and characteristics of two biographies and their authors. Baldinucci was well informed about the scandal but did not mention it, whereas, Domenico wrote in details tying to his father’s honor in the form of Pope’s pardon. The difference in these descriptions reveals characteristics of each
of the biographies.departmental bulletin pape
The Aussie value innovation. How Australia escaped the Red Queen of the global wine business
No full textThe Aussie value innovation. How Australia escaped the Red Queen of the global wine business - Using the Australian wine industry as a case study, the Author provides a possible reading of the undergone transformations of the global wine business in the last few decades. From Europe-centred to world-wide, the wine business has assisted to the enlargement of its boundaries and the rise of new features and dynamics, as well as new competition rules. The Author’s contribution is to provide a broad picture of the global wine business evolution in the light of the value innovation interpretative framework. Usually regarded at the firm level, here the Author considers that value innovation may be implemented at a country level as well, through broad planning activities and the adoption of collective strategies, facilitated by both industry and environmental factors.Value innovation, market-driving strategies, country-level strategies wine business, Australia
Comparing ease of programming in C++, Go, and Java for implementing a next-generation sequencing tool
No full textA comparison of three programming languages for a full-fledged next-generation sequencing tool
No full text
Ecocritical Hues in Christy Lefteri’s “Songbirds”: The Dissolution of the Human/Nonhuman Distinction
No full textThe human/nonhuman distinction is a significant theme in ecocriticism, which tries to undermine this dichotomy and make us rethink the human relationship with nature and other creatures. This paper argues that Christy Lefteri’s latest novel Songbirds (2021) dispels this hierarchical dualism through the portrayal of a golden mouflon ovis, a wild sheep native to the Caspian region and an extremely meaningful animal in the story: it comes to represent nature and eventually leads to the assimilation of the human and nonhuman spheres. By comparing the description of the mouflon ovis with the hedgehog in “The Mower” (1979) by Philip Larkin, I will attempt to bring to the foreground the similarities between both animal representations and the strong ecocritical hues in Lefteri’s description. Furthermore, the paper aims to show how the author depicts an interspecies and inter-elemental community – in which not only the animate dimension, but also the inanimate sphere is given value and importance – through the representation of the mouflon ovis, the motif of gold and specific passages in the novel.</jats:p
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