348 research outputs found
Eat Move Sleep : How Small Choices Lead to Big Changes
No full text#1 "New York Times" bestselling author Tom Rath delivers a book that will improve your health for years to come in three of interconnected areas: eating, moving, and sleeping.Quietly managing a serious illness for more than 20 years, Rath has assembled a wide range of information on the impact of eating, moving, and sleeping. He offers advice that will help you make good decisions automatically, in all three of these interconnected areas. With every bite you take, you will make better choices. You will move a lot more than you do today. And you will sleep better than you have in years.x+227p.;14x21c
Mean field model for turbulence transition in plane Poiseuille flow
No full textIn the pipe flow model of Dwight Barkley the main idea is to model pipe flow as an excitable, bistable medium. Using a one-dimensional FitzHugh-Nagumo-type reaction-advection-diffusion system with two variables the model captures qualitatively a surprising number of features of the turbulence transition in pipe flow. Motivated by this success, we here describe a derivation of a set of two 1+1-dimensional coupled differential equations for the closely related system of plane Poiseuille flow from the Navier-Stokes equation. The model contains terms for the production of turbulent kinetic energy, its transfer between the modes and its dissipation by viscous terms. The model shows a bifurcation to a non-trivial state and reflects some of the complex dynamics observed in direct numerical simulations
Remembering Zeami: The Kanze School and Its Patriarch
No full textThis is the publisher's official version, also available electronically from: http://dx.doi.org/10.1353/atj.2003.0027This article examines the history of the reception and popularization of the achievements
of nö’s founder, Zeami Motokiyo, as represented by three important actors of the Kanze
school: Kanze Motoakira (d. 1774), Kanze Sakon (d. 1939), and Kanze Hisao (d.
1978). Eric Rath describes how memories of Zeami helped these three actors to shape the
Kanze school’s performance practices and institutions. He reveals, too, how debate over
nö’s direction and essence has come to be framed in respect to the person considered to
be its patriarch.
Eric C. Rath is assistant professor of premodern Japanese history at the University of
Kansas. He is the author of several articles on the history of nö and the forthcoming
book The Ethos of Noh: Actors and Their Art (Harvard University Asia Center
Press)
Fabeln
No full textFifty verse fables, about one to a page. I read the first ten and found them good but not a major contribution to the fable tradition. The best of these ten are perhaps Die Zwei Hunde (9), Der Taler und der Penny (13), and Der Knabe und die Fliege (15). I have checked all my German references and resources and can find no reference to Rath. And this booklet seems one of the most undatable of all the books I have. The author has published poetry through a publisher in Omaha! There is a T of C at the end.This is a hardbound book (hard cover)Language note: GermanGeorg Rat
RATH - A Relational Adaptive Tutoring Hypertext WWW-Environment Based on Knowledge Space Theory
No full textRATH is an adaptive tutoring WWW software prototype combining a mathematical model for the structure of hypertext with the theory of knowledge spaces from mathematical psychology. Using prerequisite relationships between different items in a domain of knowledge and using the knowledge about the pupil's current knowledge state RATH presents only those links in a hypertext document to the pupil which point to a document for which he/she fulfils all prerequisites and which he/she therefore should be able to understand. In a first prototype course, this idea is applied to the field of elementary probability theory. This tiny course is based on prior research of the second author. Thus, RATH is an important step in bringing psychological theories into a working tutorial system
RATH — A relational adaptive tutoring hypertext WWW–environment based on knowledge space theory
No full textRATH is an adaptive tutoring WWW software prototype combining a mathematical model for the structure of hypertext with the theory of knowledge spaces from mathematical psychology. Using prerequisite relationships between di erent items in a domain of knowledge and using the knowledge about the pupil's current knowledge state RATH presents only those links in a hypertext document to the pupil which point to a document for which he/she ful ls all prerequisites and which he/she therefore should be able to understand. In a rst prototype course, this idea is applied to the eld of elementary probability theory. This tiny course is based on prior research of the second author. Thus, RATH is an important step in bringing psychological theories into a working tutorial system
Structural and functional characterization of PorA and PorH : the two major porins from Corynebacterium glutamicum
No full textPorA (5 kDa) et PorH (7kDa) sont les deux protéines membranaires majeures de la membrane externe de Corynebacterium glutamicum qui appartient au groupe supragénérique des bactéries Gram-positives contenant plusieurs agents pathogènes i.e. Mycobacterium tuberculosis, M. leprae et C. diphtheriae. Les deux protéines forment des canaux ioniques hétéromériques et présentent la particularité d'avoir une modification post-traductionnelle : estérification par l'acide mycolique. Les deux protéines ont été produites dans deux systèmes d'expression : chez C. glutamicum et dans un système acellulaire utilisant des extraits de E. coli. La présence ou l'absence de modification post-traductionnelle, sur les protéines produites in vivo et in vitro a été caractérisée par spectrométrie de masse MALDI-TOF. Les spectres de dichroïsme cellulaire et de RMN de PorA et PorH uniformément marquées et solubilisées en micelles de LDAO sont caractéristiques de protéines mono-disperses, partiellement structurées, et de qualité compatible avec une détermination de structure par RMN. Le test fonctionnel des protéines, par mesure de conductivité ionique après reconstitution dans une membrane lipidique (technique dite de BLM pour " black lipid membrane ") a montré que a) la modification post-traductionnelle de PorA par un acide mycolique est essentielle (contrairement à celle de PorH) b) la présence simultanée de PorA et de PorH est requise pour la formation d'un canal ionique voltage dépendant typique d'une porine. Afin de mieux comprendre l'importance de l'acide mycolique pour l'activité canal ionique, le complexe protéique PorA-PorH a été reconstitué dans son environnement naturel. Les principaux lipides de la membrane externe du C. glutamicum [Tréhalose dimycolate (TDM), tréhalose monomycolate (TMM) et cardiolipide (CL)] ont été extraits et purifiés par chromatographie d'adsorption et échange d'ions, sous forme protonée et sous forme perdeutériée. Après formation de protéoliposomes les propriétés membranaires de TDM seul ou en mélange avec CL ont été étudiées RMN du deutérium, diffusion dynamique de la lumière et microscopie électronique. L'insertion de PorA et PorH dans des vésicules de TDM a permis de mettre en évidence la reconstitution de l'hétéro-oligomère (contrairement aux micelles de LDAO). Ceci ouvre la voie à la détermination de structure 3D du complexe PorA-PorH fonctionnel par RMN solide et/ou liquide.PorA (5 kDa) and PorH (7 kDa) are two major membrane proteins from the outer membrane of Corynebacterium glutamicum which belongs to the suprageneric group of Gram-positive bacteria containing number of human pathogens such as Mycobacterium tuberculosis, M. leprae and C. diphtheriae. Both PorA and PorH have been shown to form heteromeric ion channels and to be post-translationally modified by mycolic acids (a-alkyl, beta-hydroxy fatty acids).
Both proteins were produced in their natural host with mycolic acid modification, as well as in E. coli based continuous exchange cell-free expression system and thus devoid of mycolic acid modification. The presence or absence of mycolic acid modification on in vivo and in vitro expressed proteins was confirmed by MALDI-TOF mass spectrometry. CD and NMR spectra of 15N/13C uniformly labeled PorA and PorH solubilized in LDAO micelles indicated mono-dispersed and partially folded proteins, compatible with structure determination by NMR. However, functional assays (via black lipid membrane ion-channel conductance measurements) confirmed that a complex associating both proteins is required for function and that the mycolic acid modification on PorA (but not PorH), is an absolute requirement for the formation of a voltage dependent ion-channel. To understand further the importance of covalent or non-covalent interaction of their natural lipid environment on the complex formation, the major C. glutamicum outer membrane lipids [Trehalose dimycolate (TDM), Trehalose monomycolate (TMM) and Cardiolipin (CL)] were purified using adsorption and ion exchange chromatography, both in protonated and perdeuterated form. Prior to proteoliposome reconstitution, the membrane forming properties of TDM alone or in mixture with CL were studied by 2H-NMR, Dynamic Light Scattering and Electron Microscopy. Furthermore, after in vitro reconstitution of PorA and PorH in TDM vesicles (and not in LDAO micelles or DMPC vesicles), evidence for the formation of the hetero oligomeric complex was observed. The 3D structure determination, by liquid and/or solid state NMR, of a functional PorA-PorH complex in its natural lipid environment is now feasible
The Role of the Sensing Domain (S1-S4) in TRPM8 Temperature and Menthol Dependent Gating
No full textImplications of Human TRPM8 Channel Gating from Sensing Domain and Menthol Binding Studies
No full textPark Proposal for the Vallican Archaeological Site
No full textWildland RecreationThe purpose of this report is to propose an interpretation plan and a park for the Vallican Archaelogical Site. This report deals largely with the proposal and development of an interpretative park. Some aspects of the Salishian Indians are pointed out, however, this report does not intend to be an archaeological and chronological description of the Salishian Indians and their villages
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