259 research outputs found
Ovarian steroid cell tumor in pregnancy-a rare occurrence: Report of a case and review of the literature
No full textBackground: Steroid-cell tumors of the ovary are very rare, especially during pregnancy, and they must be distinguished from luteoma of pregnancy.
Case: An 18-year-old female, gravida 3, para 1-0-1-1, at 38 weeks' of gestation, had an adnexal mass that was discovered incidentally during a Caesarean section. The tumor was excised and her male infant was normal.
Results: Histologic workup revealed the tumor to be a steroid-cell tumor, which is exceedingly rare in pregnancy.
Conclusions: Ovarian steroid-cell tumors, which are malignant one-third of the time, are difficult to distinguish from luteoma of pregnancy.Peer reviewe
Greedy Permutations and Finite Voronoi Diagrams (Media Exposition)
No full textWe illustrate the computation of a greedy permutation using finite Voronoi diagrams. We describe the neighbor graph, which is a sparse graph data structure that facilitates efficient point location to insert a new Voronoi cell. This data structure is not dependent on a Euclidean metric space. The greedy permutation is computed in O(nlog Δ) time for low-dimensional data using this method [Sariel Har-Peled and Manor Mendel, 2006; Donald R. Sheehy, 2020]
Gender and climate change framework for analysis, policy & action
No full text"This paper by Jyoti Parikh provides a framework to anlayse gender and climate change concerns keeping in view the strengths and vulnerability of poor ‐ women in particular. The author also provides policy recommendations for policies and actions.
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Texas Design Journal, Volume 1
No full textTable of Contents: ABOUT -- The Team / p. 01 -- Editors' Note / p. 03 -- IMMERSE -- Food Insecurity Among College Students / by Rohit Dinesh (p. 05) -- User Personas in Design Thinking / by Sean Feng (p. 08) -- Implication of NFTs on the Art Community / by Parth Ghawghawe (p. 11) -- Humanitarian AI and Vulnerable Populations / by Devina Parihar (p. 13) -- Making Sense of Chaos / by Eshna Parikh (p. 16) -- Student Experiences in Design / by Tanvi Shah (p. 20) -- Instructional Design / by Riya Solanki (p. 24) -- IDEATE -- Imagining the World of Engineering in Color / by Wis Escher (p. 28) -- Light the Way / by Ivy Lee (p. 30) -- Inclusive Multimodal Design / by Amy Li (p. 32) -- Austin Bus System Prototyping / by Corey Li (p. 34) -- Rethinking the Study Space Experience / by Neil Potnis (p. 36) -- PRODUCT ANALYSIS -- Understanding XR / by Celine Low (p. 42) -- Microtransactions in Gaming / by Bruce Luo (p. 44) -- Agile Development / by Ranjan Veludandi (p. 47) -- Robinhood: An Unworthy King / by Roger Zhong (p. 50) -- REFERENCES p. 53Undergraduate Studie
The Neuropeptide VGF is Reduced in Human Bipolar Postmortem Brain and Contributes to Some of the Behavioral and Molecular Effects of Lithium
No full textRecent studies demonstrate that the neuropeptide VGF (non-acronymic) is regulated in the hippocampus by antidepressant therapies and animal models of depression and that acute VGF treatment has antidepressant-like activity in animal paradigms. However, the role of VGF in human psychiatric disorders is unknown. We now demonstrate using in situ hybridization that VGF is downregulated in bipolar disorder in the CA region of the hippocampus and Brodmann’s Area 9 (BA9) of the prefrontal cortex. The mechanism of VGF in relation to LiCl was explored. Both LiCl intraperitoneally (IP) and VGF intracerebroventricularly (ICV) reduced latency to drink in novelty-induced hypophagia and LiCl was not effective in VGF+/- mice suggesting that VGF may contribute to the effects of LiCl in this behavioral procedure that responds to chronic antidepressant treatment. VGF by intrahippocampal injection also had novel activity in an amphetamineinduced hyperlocomotion assay thus mimicking the actions of LiCl injected IP in a system that phenocopies manic-like behavior. Moreover, VGF+/- mice exhibited increased locomotion following amphetamine and did not respond to LiCl, suggesting that VGF is required for the effects of LiCl in curbing the response to amphetamine. Finally, VGF by ICV in vivo activated the same signaling pathways as LiCl and is necessary for the induction of MAPK and AKT by LiCl thus lending insight into the molecular mechanisms underlying the actions of VGF. The dysregulation of VGF in bipolar disorder as well as the behavioral effects of the neuropeptide similar to LiCl suggests that VGF may underlie the pathophysiology of bipolar disorder.Peer reviewe
MMU: 01/14/19–01/20/19
No full textMMU January14 - 20 Stanford Professor Marcus Cole Appointed Dean of Notre Dame Law School Welcome Our New Registrar Jenny Fox! RSVP: A Conversation with Nina Totenberg Mass Schedule Announcement - Weekly Bible Study Legal Writing Center Invitation To All NDLS Student Groups Health & Wellness Information This Week @ NDLS Song of the Week Meme of the Week 1L of the Week: Parth Parikh 3L of the Week & Announcing Kesh\u27s Korner : Harkesh Patel Long Reads of the Wee
Assessing the effect of exercise on dial-task cognitive impairment in patients with Parkinson's disease
No full textThis work was produced while the author was an undergraduate student in the Summer Research Institute of the Ronald E. McNair Post Baccalaureate Degree Achievement Program at Rutgers University
Bio-Feedback Device for Meditation
No full textIn today’s fast-paced lifestyle people have a lot of stress. However, it is very hard to notice and even harder to reduce stress in a stressful environment. A clinical inspection may be required to measure the stress accurately. Meditation is widely used as an exercise to feel more relaxed. The aim of this project is to develop a framework that manipulates data from multiple sensors to calculate the stress level. The measured stress level could be given as a Bio-Feedback which indicates the effectiveness of meditation. A machine learning algorithm is used to process the data. As the data points are extremely important for a machine learning algorithm to work effectively, it requires a robust, scalable, and flexible framework for data management. This objective is achieved by virtually connecting the wearable device to a cloud service. This connection is made possible by a mobile application which serves as a human-computer interface. Data from various sensors are collected in the wearable device, through Bluetooth Low Energy (BLE) interface. These data are then sent to the mobile application which passes them to a cloud service. The cloud service provides not only a proper means of storage for the data but also acts as a central control for the whole system. Apart from this production-oriented implementation, a research-oriented implementation was also developed for prototyping an Application Specific Integrated Circuit (ASIC).Includes bibliographical references (pages 18-18)California State University, Northridge. Department of Electrical and Computer Engineering
Examining mechanical properties of single acetaminophen crystal using nanoindentation methods
No full textThe pharmaceutical industry incurs substantial loss in revenue and consumer confidence with inefficient manufacturing practices. Large scale processing of organic compounds is challenging due to its sensitivity to environmental conditions and the unpredictable breakage behavior of tablets under applied stress. Tablet compaction and particle size reduction through milling induces variability in the end product. Variability in powder flow, stress induced transformation in polymorphic compounds, re-crystallization after compaction, and lack of content uniformity are some factors that translate into poor product quality. These challenges can be partially resolved by a better understanding of mechanical properties of crystalline pharmaceutical materials at single particle level. The endeavor of this study was to understand the breakage behavior of various planes of a single Acetaminophen crystal using nanoindentation instrumentation. The results of the study indicated that the Acetaminophen crystal is anisotropic with respect to hardness and Young’s modulus values. Analysis of the load-depth curve, discontinuities on the loading and unloading cycle were observed, as well as pop-in events during constant load intervals. Furthermore, the frequency of pop-in events on the loading depth curve was found to correlate with the elasticity of the planes in question. It was also apparent that the organic compound was sensitive to environmental conditions. Varying strain rates effects different planes of the same crystal and also in adhesion reflected sensitivity to environmental conditions. The exact mechanism by which the crystal deforms is still unknown. However it is theorized that it could be through partial dislocations and crack propagations.M.S.Includes bibliographical referencesby Hiral Parik
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