1,721,037 research outputs found
Branch Retinal Vein Occlusion: Classification and Treatment
No full textBranch retinal vein occlusion (BRVO) refers to a heterogeneous group of disorders with different clinical aspects, courses, and probably therapy. Depending on the site of the arteriovenous crossing, we can roughly divide BRVO into 3 main groups: major BRVO, hemispheric retinal vein occlusion, and macular BRVO. Main treatment options include laser treatment, corticosteroid administration, anti-VEGF drugs, and sheathotomy with or without vitrectomy. Laser photocoagulation, as demonstrated by the Branch Vein Occlusion Study, represents the gold standard for the treatment of macular edema and ocular neovascularization following BRVO. The limited functional outcomes achievable by means of laser treatment have prompted researchers to try alternative options, with varying results. The recent introduction of combined therapies for macular edema may provide a superior approach in an attempt to improve and stabilize visual acuity over a long-term follow-up. Copyright (C) 2009 S. Karger AG, Base
Temporary Intraocular Pressure Lowering by Photodynamic Therapy in Pseudoexfoliation Glaucoma
No full textBACKGROUND AND OBJECTIVE: The aim of the study was to ascertain whether photodynamic therapy (PDT) with verteporfin is able to reduce the blood-aqueous barrier impairment in eyes affected by pseudoexfoliative glaucoma (PESG) with consequent intraocular pressure (IOP) lowering. PATIENTS AND METHODS: Five patients with poorly controlled PESG were selected. The laser energy was directed to the anterior chamber angle and the iris surface by means of a Goldmann lens. RESULTS: IOP reduction was registered 1 month after PDT and lasted 3 months, reaching the values registered before PDT after that. Iris fluorescein angiography 1 week and 1 month after PDT showed reduced dye leakage, but the same amount of dye leakage visible before PDT was detectable 3 months later. CONCLUSION: PDT can reduce the breakdown of the blood-aqueous barrier and can lower the IOP temporarily in eyes affected by PESG. Further studies are needed to analyze the biochemical changes after PDT in aqueous humor
Fundus autofluorescence in subfoveal choroidal neovascularisation secondary to Pathological myopia
No full textOne-Year Outcomes of Aflibercept in Recurrent or Persistent Neovascular Age-Related Macular Degeneration
No full textJuxtafoveal Choroidal Neovascularization Secondary to Persistent Placoid Maculopathy Treated with Intravitreal Bevacizumab
No full textPurpose: To describe a case of persistent placoid maculopathy (PPM) associated with juxtafoveal choroidal neovascularization (CNV) treated with intravitreal bevacizumab injection (IVBI). Design: Interventional case report. Methods: A 60-year-old patient referred for sudden vision loss was diagnosed with PPM complicated by a disciform scar in the right eye and juxtafoveal CNV in the left eye, undergoing 2 IVBIs. Results: Best-corrected visual acuity passed from 20/32 to 20/20 after 2 IVBIs, with complete resolution of intraretinal and subretinal fluid and disappearance of fluorescein leakage. Conclusions: IVBI is a promising treatment option for juxtafoveal CNV secondary to PPM
Treatment options for diffuse diabetic macular edema
No full textPURPOSE. To describe the current management of diffuse diabetic macular edema (DOME). METHODS. Review and discussion of the literature regarding DOME. RESULTS. Diffuse diabetic macular edema is a condition that can be managed by means of several treatment options, including focal/grid laser photocoagulation, intravitreal or periocular corticosteroids, intravitreal anti-vascular endothelial growth factor (VEGF), and vitrectomy with or without internal limiting membrane peeling. CONCLUSIONS. Even though there is no randomized clinical trial specifically designed to assess the best treatment approach for DOME, new therapeutic approaches based on intravitreal injections of corticosteroid and anti-VEGF molecules offer new hope for its management
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