166,433 research outputs found

    A grammar of sentiment thinking about sentimental jewellery towards making new art about love and loss.

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    Submitted in partial fulfilment of the requirements of the University of Wolverhampton for the Degree of Doctor of PhilosophyThis practice-led research project explores English and French sentimental jewellery of the Victorian period. ‘Sentimental jewellery’ or ‘message jewellery’ denotes jewellery created to function as a tangible expression of feeling between donor and recipient, mediated through complex narratives relating to its exchange. These artefacts codify emotion through use of complex visual languages, employing the symbolic and coded use of gems, human hair, emblems, words and wordplay. The research has expanded to encompass memorial garments known as ‘widows weeds’. The aims of the research have been threefold: firstly, to add to understanding and interpretation of aspects of Victorian sentimental jewellery and associated craft practices; secondly, to explore the metaphors and narratives inherent within them; thirdly, to test the visual and technical possibilities of knowledge thus gained to address human feeling through art. Outcomes take the form of a body of new artwork and a written thesis, which are designed to be mutually informing. Together, they articulate my response to the project’s central question: can consideration of the ‘grammar of sentiment’ at work in Victorian sentimental jewellery yield new possibilities, through fine art practice, for communicating love and loss in the 21st century? The four artworks that are a main output of the research take the forms of: REGARD:LOVEME, an artist’s book exploring gem codes and wordplay; Plocacosmos, a set of hairworking trials; The Cyanotypes, which reflect upon the materiality and aesthetic of the amatory locket; and Widows Weeds, a large format photographic installation, which considers the materiality and lineage of mourning cloth. Collectively, they explore the typology of the sentimental artefact through development of text/image vocabularies that are conceived as providing a ‘grammar of sentiment’ through which to articulate aspects of human feeling. It is this exploration that constitutes my main contribution to knowledge

    Contact lens-based expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction: Crossover control

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    [No abstract available]Di Girolamo N, 2009, TRANSPLANTATION, V87, P1571, DOI 10.1097-TP.0b013e3181a4bbf2; Ozbek Z, 2006, CORNEA, V25, P245, DOI 10.1097-01.ico.0000176602.49258.ea; Parmar DN, 2006, AM J OPHTHALMOL, V141, P299, DOI 10.1016-j.ajo.2005.09.0080

    [Report to Chief J. E. Curry, by an unknown author #1]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    [Report to Chief J. E. Curry, by an unknown author #2]

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    Report to Chief J. E. Curry, by an unknown author. The report contains a list of officers who gave depositions to the United States Attorney

    Speech testing in adult audiology (Parmar et al., 2022)

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    Objective: The aim of this study was to evaluate hearing health care professionals’ (HHPs) speech testing practices in routine adult audiology services and better understand the facilitators and barriers to speech testing provision. Design: A cross-sectional questionnaire study was conducted. Study Sample: A sample (N = 306) of HHPs from the public (64%) and private (36%) sectors in the United Kingdom completed the survey. Results: In the United Kingdom, speech testing practice varied significantly between health sectors. Speech testing was carried out during the audiology assessment by 73.4% of private sector HHPs and 20.4% of those from the public sector. During the hearing aid intervention stage, speech testing was carried out by 56.5% and 26.5% of HHPs from the private and public sectors, respectively. Recognized benefits of speech testing included (a) providing patients with relatable assessment information, (b) guiding hearing aid fitting, and (c) supporting a diagnostic test battery. A lack of clinical time was a key barrier to uptake. Conclusions: Use of speech testing varies in adult audiology. Results from this study found that the percentage of U.K. HHPs making use of speech tests was low compared to that of other countries. HHPs recognized different benefits of speech testing in audiology practice, but the barriers limiting uptake were often driven by factors derived from decision makers rather than clinical rationale. Privately funded HHPs used speech tests more frequently than those working in the public sector where time and resources are under greater pressure and governed by guidance that does not include a recommendation for speech testing. Therefore, the inclusion of speech testing in national clinical guidelines could increase the consistency of use and facilitate the comparison of practice trends across centers. Supplemental Material S1. A summary of survey study results provided by HHPs in relation to the implementation of speech testing practices in adult audiology across the world.  Supplemental Material S2. Survey: Speech testing in Adult Audiology (UK). Supplemental Material S3. All survey responses.  Parmar, B. J., Rajasingam, S. L., Bizley, J. K., & Vickers, D. A. (2022). Factors affecting the use of speech testing in adult audiology. American Journal of Audiology. Advance online publication. https://doi.org/10.1044/2022_AJA-21-00233</p

    Murder on the mountain: author talk with Peter J. Wosh

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    Author talk by Peter J. Wosh on May 5th, 2022, on his book, "Murder on the Mountain: crime, passion, and punishment in gilded age New Jersey.

    Mr. Melvin J. Collier, RWWL AUC, June 2011

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    This video is a conversation with Mr. Melvin J. Collier. Mr. Collier talks about his book, "From Mississippi to Africa: A Journey of Discovery". Daniel Le, AUC Woodruff Library, is the interviewer

    Royston−Parmar flexible parametric survival model to predict the probability of keratoconus progression to corneal transplantation

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    Purpose: To assess a Royston−Parmar flexible parametric survival model to generate a personalised risk profile for keratoconus progression. Methods: We re-analysed a historic database of 2723 individuals with keratoconus. A Royston−Parmar survival model was fitted to predict the likelihood of the worse eye progressing to corneal transplantation. We used a backwards selection multivariable fractional polynomial procedure to assist with selection of covariates and identify appropriate transformation(s) to retain in the final model. Time-dependent receiver operating characteristic (ROC) curves from censored survival data using the Kaplan−Meier (KM) method were computed to visually assess how well the model identified eyes likely to progress. Results: In all, 5020 eyes from 2581 patients were available for model development. This included 2378 worst affected eyes, and 313 eyes that progressed to transplantation. The best fitting model [df = 1: Bayes information criterion (BIC) = 1573] included three variables, keratometry [hazard ratio (HR) 0.36: 95% confidence limits (CI) 0.32–0.42], age at baseline [HR 0.97: CI 0.95–0.99] and ethnicity [HR 3.92: CI 2.58–5.95]. Specificity at 1 year was 92.8% (CI 90.4−95.2%) with a corresponding sensitivity of 64.6% (CI 58.9−60.0%). These three prognostic factors account for 41.3% (CI 33.6 – 48.2%) of the variation among the survival curves. Conclusion: Researchers should consider the Royston−Parmar model as an alternative to the Cox model. We illustrate the concepts and our results may lead to better tools that identify individuals at high risk of keratoconus progression.</p

    3D biomaterial models of human brain disease

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    Inherent limitations of the traditional approaches to study brain function and disease, such as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro cell culture systems. These systems, products of multidisciplinary efforts encompassing stem cell biology, materials engineering, and biofabrication, have quickly shown great potential to mimic biochemical composition, structural properties, and cellular morphology and diversity found in the native brain tissue. Crucial to these developments have been the advancements in stem cell technology and cell reprogramming protocols that allow reproducible generation of human subtype-specific neurons and glia in laboratory conditions. At the same time, biomaterials have been designed to provide cells in 3D with a microenvironment that mimics functional and structural aspects of the native extracellular matrix with increasing fidelity. In this article, we review the use of biomaterials in 3D in vitro models of neurological disorders with focus on hydrogel technology and with biochemical composition and physical properties of the in vivo environment as reference

    A Tripartite Post-Recession Rebalancing

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    In this latest Advance & Rutgers Report, entitled “A Tripartite Post-Recession Rebalancing,” Dean James W. Hughes and Professor Joseph J. Seneca deliver an incisive assessment of the current market conditions and obstacles in the path of our economic recovery. They offer a statistical cautionary tale that the private and public sector need to hear and acknowledge in order for the economy to make continued progress.This report was published as Issue Paper Number 7, November 2011, in Advance & Rutgers Report
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