692 research outputs found

    Progress report on the cost-effectiveness of X-linked adrenoleukodystrophy newborn screening

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    This research was supported by the Undergraduate Research Opportunities Program (UROP).Parikh, Aditya; Miller, Weston. (2017). Progress report on the cost-effectiveness of X-linked adrenoleukodystrophy newborn screening. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/187824

    sj-pdf-1-sri-10.1177_15533506221094956 – Supplemental Material for The Impact of Homemade Laparoscopic Box Trainers on Medical Student Surgical Skills: A Randomized Control Pilot Study

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    Supplemental Material, sj-pdf-1-sri-10.1177_15533506221094956 for The Impact of Homemade Laparoscopic Box Trainers on Medical Student Surgical Skills: A Randomized Control Pilot Study by Harrison Seltzer, Emma Swayze, Letty Thottathil, John Dewey, Jordan Jabara, Aditya Mehta, John Frederick, Paul Yousif, Sonia Parikh, Angie Tsuei, Lisa Miller, and L Silvia Linares in Surgical Innovation</p

    Dentigerous Cyst

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    Dentigerous Cyst Dental School Radiology Presentation : Dentigerous Cyst Author : Tadinada, Aditya Medical Subject : Dentigerous Cyst, Odontogenic Cysts Clinical Presentation Description : Radiolucency arising from the CEJ of an unerupted tooth Location of Abnormality : Posterior Mandible Radiological Features : Radiolucency arising from the CEJ of an unerupted tooth DDx Description : Dentigerous cyst, odontogenic keratocyst, ameloblastoma Type of Image : Panoramic Radiograph Digital Publisher : UCONN Health Center : Kilham, Jessica Format : jpg Date : 201

    Risk and Return Analysis of Selected Flexi Cap Mutual Funds

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    Mutual funds are considered by the investors as an ideal investment for people who are not having huge sum of money and wish to invest in a portfolio of stocks wherein the share price is quite high. The investors may or may not be aware about the ways investment could be done in stock market and there are different investment options which are available in the market based on a different risk and return. Flexi cap mutual funds offerfund managers a freedom for investing across themes/ sectors and market capitalizations. In Flexi Cap mutual funds, the fund managers could invest on the basis of outlook of market. These schemes generally recommended to the moderate investors for creating wealth over long time period. This study is based on the evaluation of risk and return of different flexi cap mutual funds and compares the performance of these funds so as to find the best flexi cap fund based on different measures of return and risk. Based on the average of the monthly returns, though it is negative, the lowest average negative return is of Aditya Birla and Parag Parikh Flexi Cap mutual funds. The maximum times the highest return has been of Parag Parikh Flexi Cap mutual fund during different quarters. Based on the average Annual return, highest return is of Parag Parikh Flexi Cap mutual fund, followed by UTI Flexi Cap fund, SBI Flexi Cap fund, PGIM Flexi Cap fund and Aditya Birla Flexi Cap mutual fund

    Is retrograde intrarenal surgery the game changer in the management of upper tract calculi? A single-center single-surgeon experience of 131 cases

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    Introduction: Success of any modality for stone disease needs to be evaluated in terms of Stone Free Rates (SFR), auxiliary procedures needed; complications and follow up. SFR in RIRS is subject to parameters like stone burden, location, number, hardness, composition; calyceal and ureter anatomy; use of ureteric access sheath (UAS); surgeon experience etc. Methods: The aim of this study is to evaluate the efficacy and safety of RIRS for managing upper tract stones. The objectives include evaluating SFR in RIRS in relation to stone burden, location and number. Other objectives include evaluating SFR after re RIRS in relation to stone burden, necessity of pre DJ stenting, use of UAS and post operative complication rate. 131 patients operated by single surgeon for single/multiple renal and/or upper ureteric stones were evaluated. Stone size > 3 mm on follow up CT KUB was considered as residual. Re RIRS was required for residual stones. Results: The overall SFR was 76%. SFR were statistically lower with stone burden > 1.5 cm, lower calyceal stones and single stones with stone burden > 1.5 cm. SFR was 90% after 2nd RIRS and 98.5% after 3rd RIRS procedure. No significant difference in SFR was noted between single v/s multiple stones, single calyx v/s multiple calyx stones and renal v/s upper ureteric stones. No major complication was noted. Conclusion: Larger stone burden and lower calyceal location are important factors deciding SFR in RIRS. With auxiliary procedure, RIRS is safe and effective compared to PCNL

    Design, modeling and real-time monitoring of continuous powder mixing processes

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    Continuous processing is an advantageous alternative for the current methods used in the pharmaceutical manufacturing. Important advantages that it offers include smaller equipment footprint, reduced efforts in the scale-up work, and the potential to utilize already continuous processes to make the entire manufacturing more efficient. In the current pharmaceutical manufacturing environment, powder mixing process is carried out in the batch mode. The necessary methods and guidelines to design an equivalent continuous process are not well established. The work presented in this dissertation focuses on the characterization, design and optimization of a continuous powder mixing process for pharmaceutical powders. A systematic study was performed of the effects of process and design variables, and material properties involved in the continuous powder mixing process. The bulk powder flow behavior was characterized using the residence time distribution (RTD) measurement approach. Impeller speed, material bulk density and impeller design greatly influenced the mean residence time. With increasing impeller speed, mechanical fluidization was observed, which significantly affected axial dispersion coefficients. Intermediate rotation rates exerted maximum strain on the material, which leads to maximum homogenization. The strain measurements correlated well with the properties of tablets including content uniformity and tablet hardness. Mixing performance was largely dominated by the material properties of the mixture, and the blend uniformity measurement was affected by the sample size analyzed. An experimental protocol was developed to measure the blend uniformity in the in-line mode, and a methodology was further built to quantitatively relate the in-line NIR measurements with the off-line wet chemistry measurements. Considering the shear limitations of the continuous bladed mixer, alternative blending strategies, suitable for blending of cohesive materials were also demonstrated. A combination of a high-shear mixing followed by a low-shear mixing process provided the optimal mixing performance. The predictive understanding of the continuous powder mixing process developed in this dissertation can assist towards the design and development of a fully controlled continuous manufacturing process.Ph. D.Includes bibliographical referencesIncludes vitaby Aditya U. Vanaras

    A rare case of small cell carcinoma of urinary bladder in a bladder diverticulum: Case report and review of literature

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    Small cell carcinoma of the urinary bladder (SCCB) is a rare and aggressive non-urothelial tumour of the urinary bladder. It represents neuro endocrine type of malignancy, being diagnosed on histopathology and immuno histo chemistry. Bladder diverticulum tumours are rare and present with early lamina propria invasion. Furthermore, the risk of bladder perforation is high during resection due to the lack of muscle. Thus, these tumours have a risk of being under-staged and have a poor prognosis. Till now, very few cases have been reported of SCCB in bladder diverticulum. Multi-modality management in the form of combined chemotherapy and surgery is required for the optimal management. We report this rare case and review the literature for the management of SCCB in bladder diverticulum

    Crystal Dynamics and Anharmonic Properties of Bi-Pb-Tl Alloys

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    Title: Crystal Dynamics and Anharmonic Properties of Bi-Pb-Tl Alloys, Author: Aditya P. Roy, Location: ThodeThe crystal dynamics and anharmonic properties have been investigated in disordered alloys of Bi-Pb-Tl using slow neutron spectrometry. Damping of phonons caused by phonon-phonon interaction and the effect of the force constant disorder on the lifetime of the phonons have been studied in the alloys. Measurements of the coefficients of thermal expansion are reported. An experimental method of determining the lattice frequency spectra by coherent inelastic scattering of neutrons from polycrystalline materials is described.ThesisDoctor of Philosophy (PhD

    On the two-potential constitutive modelling of rubber viscoelastic materials

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    U of I Only Restriction Lifted for Item 93166 on 2018-07-08T09:15:36Z."This work lays out the specialization of the two-potential constitutive framework --- also known as the ""generalized standard materials'' framework --- to rubber viscoelasticity. Inter alia, it is shown that a number of popular rubber viscoelasticity formulations, introduced over the years following different approaches, are special cases of this framework. As a first application of practical relevance, the framework is utilized to put forth a new objective and thermodynamically consistent rubber viscoelastic model for incompressible isotropic elastomers. The model accounts for the non-Gaussian elasticity of elastomers, as well as for the deformation-enhanced shear thinning of their viscous dissipation governed by reptation dynamics. The descriptive and predictive capabilities of the model are illustrated via comparisons with experimental data available from the literature for two commercially significant elastomers."Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2018-05-01The student, Aditya Kumar, accepted the attached license on 2016-04-21 at 16:42.The student, Aditya Kumar, submitted this Thesis for approval on 2016-04-21 at 17:40.This Thesis was approved for publication on 2016-04-25 at 13:53.DSpace SAF Submission Ingestion Package generated from Vireo submission #9421 on 2016-07-07 at 13:50:34Made available in DSpace on 2016-07-07T20:27:55Z (GMT). No. of bitstreams: 2 KUMAR-THESIS-2016.pdf: 837141 bytes, checksum: 4cd6a13625dabb966b6db0afa249edcc (MD5) LICENSE.txt: 4209 bytes, checksum: 0e09e0cd09aa5811ed8246d9f3eb6e6d (MD5) Previous issue date: 2016-04-25Embargo set by: Seth Robbins for item 93166 Lift date: 2018-07-07T20:28:14Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemEmbargo set by: Seth Robbins for item 93166 Lift date: 2018-07-07T20:35:34Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD syste

    LIPIcs

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    An automaton is history-deterministic if its nondeterminism can be resolved on the fly, only using the prefix of the word read so far. This mild form of nondeterminism has attracted particular attention for its applications in synthesis problems. An automaton is guidable with respect to a class C of automata if it can fairly simulate every automaton in C, whose language is contained in that of . In other words, guidable automata are those for which inclusion and simulation coincide, making them particularly interesting for model-checking. We study the connection between these two notions, and specifically the question of when they coincide. For classes of automata on which they do, deciding guidability, an otherwise challenging decision problem, reduces to deciding history-determinism, a problem that is starting to be well-understood for many classes. We provide a selection of sufficient criteria for a class of automata to guarantee the coincidence of the notions, and use them to show that the notions coincide for the most common automata classes, among which are ω-regular automata and many infinite-state automata with safety and reachability acceptance conditions, including vector addition systems with states, one-counter nets, pushdown-, Parikh-, and timed-automata. We also demonstrate that history-determinism and guidability do not always coincide, for example, for the classes of timed automata with a fixed number of clocks
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