5 research outputs found
Drying Kinetics and Modelling of Mass Transfer in Thin Layer Convective Drying of Pineapple
No full textMathematical modelling and estimation of effective moisture diffusivity and activation energy, exergy analysis of thin layer drying of pineapple
No full textDrying Kinetics and Modelling of Mass Transfer in Thin Layer Convective Drying of Pineapple
No full textThe aim of the investigation was to study the drying characteristics of pineapple at different
temperatures of 55, 60, 65, 70 and 75°C with 1.5 m/ s constant air velocity. In the present study, the
best drying model was selected to describe the drying behaviour, and to develop the moisture
profile using COMSOL. Based on the best criteria, Verma et al. was chosen as the best fit to the
experimental data. The predicted moisture ratio values obtained from COMSOL simulation and
Verma et al. were good agreement with the experimental data
Effects of fisetin on hyperhomocysteinemia- induced experimental endothelial dysfunction and vascular dementia
No full textThis study was designed to investigate the effect of fisetin (FST) on hyperhomocysteinemia (HHcy) - induced experimental endothelial dysfunction (ED) and vascular dementia (VaD) in rats. Eight groups of Wistar rats were randomly divided as control, vehicle control, L-methionine, FST (5, 10 and 25 mg/kg, p.o.), FST-per se (25 mg/kg, p.o.) and donepezil (0.1 mg/kg, p.o.) respectively. L-Methionine administration (1.7 g/kg, p.o.) for 32 days induced HHcy. ED and VaD induced by HHcy were determined by vascular reactivity measurements, behavioral analysis using Morris water maze and Y-maze along with a biochemical and histological evaluation of thoracic aorta and brain tissues. Administration of L-methionine developed behavioral deficits, triggered brain lipid peroxidation (LPO) and compromised brain acetylcholinesterase activity (AChE) and reduced the levels of brain superoxide dismutase (SOD) ,brain catalase (CAT),brain reduced glutathione (GSH) and serum nitrite, increased serum homocysteine and cholesterol levels. These effects were accompanied by decreased vascular NO bioavailability, marked intimal thickening of the aorta and multiple necrotic foci in brain cortex. HHcy induced alterations in the activities of SOD, CAT, GSH, AChE, LPO, behavioral deficits, ED and histological aberrations were significantly attenuated by treatment with fisetin in a dose-dependent manner. Collectively our results indicate that fisetin exerts endothelial and neuroprotective effects against HHcy-induced ED and VaD.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
