38 research outputs found
Professor Sergei Semjonovic Golovin (1866-1931): A Pioneer of Ocular Surgery
No full textProfessor Sergei Semjonovic Golovin (1866-1931) is considered as one of the founders of ophthalmology in Russia. He received a worldwide reputation thanks to his achievements in ocular surgery and pathology. He introduced new surgical techniques such as Golovin's operation (Exenteratio orbitosinualis), Golovin's osteoplastic frontal sinus operation, ligation of orbital veins, and opticociliary neurectomy. He also introduced his "cytotoxic theory" to interpret sympathetic ophthalmia. He was a reputable professor of ophthalmology. © The Author(s) 2017
Exploring the Innovation Phase of Radically-New High-Tech Products: An Investigation of Two Historical Cases of AIDC Technologies
No full textThe transformation of a new technological principle into a marketable product usually signifies a long and risky route for organizations engaged in the commercialization of radically new high-tech products. New products often fail to make it to the market, are delayed for their market introduction, or are withdrawn shortly after their market introduction. The period that spans from invention to (first) market introduction of radically new high-tech products (i.e. the innovation phase) has been found to last on average ten years (Ortt, 2010). Furthermore, the duration of the innovation phase may significantly vary per product. Arguably, this duration is suspected to encompass several barriers and strategic interaction. This thesis explores the erratic nature of the innovation phase by asking “what are the key actors and factors that facilitate or hamper innovation?”, “how are these interrelated?”, and “what strategies can be derived for organizations?”. The issue of successfully developing and commercializing innovative products pertains to a vast literature and several theoretical domains that have different units of analysis and orientation towards the innovation process. Although, theories propose different actors and factors as barriers and/or facilitators to bringing new technological products to the market, a comprehensive picture of how these actors and factors interact and influence the course of the innovation phase is lacking. This thesis argues that a more complete picture of the innovation phase can be achieved by synthesizing a wide range of notions from different theories. In turn, this can assist the process of devising more holistic innovation strategies. For the purpose of this research, a two-phase methodological approach has been followed. The first phase consists of a literature review that selectively examines the fields of: Strategic Niche Management, Organizational Capabilities/Characteristics and Innovation, the Valley of Death in Innovation, and the Fuzzy Front End of Innovation. The project theorizes that the concepts presented by these theories can be better understood if categorized along three broad and separate but interrelated levels: (i) a macro-level that comprises the market environment within which transitions to new technological regimes take place; (ii) a meso-level that is composed by the organization that considers the commercialization of radically new technologies; and (iii) a micro-level that consists of the project within which a new product is developed. The examined theories emphasize interrelations among factors that are usually found at the same level of analysis. However, this study attempts to reveal interaction among factors both within and across these levels. The integration of actors, factors, and interrelations is realized through the construction of a multi-level framework based on the distinction of the three aforementioned levels of interaction. The framework serves both as a static list of key influencing actors and factors, and for addressing interrelations among them. It is presumed that the same actors and factors can act as barriers and/or facilitators to innovation. Several simple mechanisms of interaction between factors are proposed, such as barriers reinforcing other barriers, or facilitators diminishing barriers. These mechanisms concern interaction among factors, both within and across levels. Consequently, more advanced mechanisms are derived, such as a chain of reinforcing barriers might create a negative feedback loop that possibly blocks radical innovation. A web consisting of barriers and facilitators that may have multiple causes and effects at the same time is revealed. With regard to the interaction among actors, a systematic way of interrelating is more difficult because of their complex nature. The framework is illustrated and refined in a second phase, with the investigation of two historical cases of Automatic Identification and Data Capturing (AIDC) technologies: Radio Frequency Identification and barcode. The analysis, which is based on secondary published documentation, enables not only the identification of several actors and factors, but also demonstration of interactions among factors and factors both within and across the distinguished levels. In addition, generic strategies for companies to cope with the innovation phase are derived as a result of empirical observations within the case studies. The major outcome of the project is the multi-level framework to address key actors and factors, and interrelationships that influence the innovation phase. Macro-level factors include: Technological Factors, Economic Factors, Competition, Supply Networks, Infrastructure & Maintenance Networks, Social Networks, Psychological & Cultural Factors, Social & Environmental Effects, Government Policy, Legislation & Regulation (Laws, Standards and Rules), Institutional Risk, and Competition; Meso-level factors include: Scientific Knowledge and Firm-Specific Techniques, Technical Systems, Managerial Systems, Organizational Culture and Values, and Financial Resources; and Micro-level factors include: Opportunity, Product Concept & Definition, Project Planning, and New Product Development process. With regard to the actors, Macro-level actors include: Governments, Research Institutes, Universities, Industries, Policy-makers, Regulators, Suppliers, Providers of Complementary Products, Potential Users (Early Adopters), Scientists, and Autonomous Entrepreneurs; Meso-level actors include: (Network of) Companies-Developers, Top - management, Executives, and Consultants; and Micro-level actors include: Product Champions, Project Managers, and Project Teams. Moreover, the emergence and influence of actors and factors within the case studies, indicated the following four key generic strategies for companies to deal with to the innovation phase: (i) Collaboration with other Knowledge Producing Institutions, (ii) Strategic Patent Acquisition, (iii) Working together with Potential Early Adopters, and (iv) Long-term Investment in Technology. These should not be viewed as competing alternatives, but, rather as mutually supporting options for firms that are engaged with development and/or commercialization efforts. The overall findings suggest a rather complex landscape for organizations seeking the commercialization of radical high-tech products. The innovation phase is characterized by significant dynamics in terms of the actors involved with research and/or NPD projects. Moreover, the successful market introduction of new technologies is more likely to be determined by a dynamic combination of factors functioning at different levels. Companies might take advantage of developments at all levels and successfully market a new product, without necessarily being active in investments for a long period of time. However, the context matters. The context might refer to the type of application (i.e. more systemic or less systemic), or the degree of complexity of the technology (i.e. relatively simple or complex systems). Finally, caution is required as there is no panacea for the challenges faced by actors during the innovation phase. Solutions must be tailored to the specific context with which development and commercialization efforts are confronted.Technology, Policy and ManagementValues, Technology and Innovation / Economics of Technology and InnovationsManagement of Technolog
Polymorphism analysis of miR182 and CDKN2B genes in Greek patients with primary open angle glaucoma
No full textGlaucoma is a progressive optic neuropathy resulting from retinal ganglion cells death; it represents one of the leading causes of irreversible blindness worldwide. Although, primary open angle glaucoma (POAG) is the most common type of the disease, the pathogenesis of POAG and the genetic factors contributing to disease development remain poorly understood. The aim of this study was to investigate whether the polymorphisms rs76481776 in miR182 gene and rs3217992 in cyclin-dependent kinase inhibitor-2B (CDKN2B) gene are risk factors for POAG in a series of patients of Greek origin. A case-control study was conducted including 120 patients with POAG and 113 unaffected healthy controls of Greek origin, surveyed for polymorphisms with potential correlation to POAG. DNA from each individual was tested for the miR182 rs76481776 and CDKN2B rs3217992 polymorphisms. Regarding the miR182 rs76481776 polymorphism, the T allele occurred with significantly higher frequency in POAG patients compared to controls (OR: 2.62, 95% CI: 1.56-4.39; p = 0.0002). The CDKN2B rs3217992 A allele frequency was found significantly increased in POAG patients compared to healthy individuals (OR: 1.72, 95% CI: 1.18-2.49; p = 0.005). Therefore, both rs76481776 polymorphism in miR182 gene and rs3217992 polymorphism in CDKN2B gene seem to be associated with the development of POAG in a Greek population. The carriers of the T allele of rs76481776 in miR182 and the carriers of the A allele of rs3217992 in CDKN2B have an increased risk of developing POAG. © 2020 Moschos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Clinical and multifocal-electroretinographic findings of congenital tilted disc syndrome associated with choroidal neovascularization: A case report
No full textPurpose: To report a case of a tilted disc syndrome associated with choroidal neovascularization. Methods: A 55-year-old male patient presented with blurred vision and metamorphopsia of the left eye. He underwent complete ophthalmologic examination, fluorescein angiography, optical coherence tomography (OCT) and multifocal-electroretinogram (mf-ERG). Results: All features are consistent with a tilted disc syndrome complicated with a small neovascular membrane. OCT confirmed the presence of a serous retinal detachment. Mf-ERG confirmed a decrease of electrical activity of the photoreceptors in area 1 (fovea). The patient refused to be treated. Conclusion: Macular serous retinal detachment due to subretinal leakage is a rare complication of tilted disc syndrome. To the author's knowledge, this is the first time a tilted disc syndrome with choroidal neovascularization is documented by means of OCT and mf-ERG. These are the only objective tools in order to assess objectively the anatomical and functional damage accordingly. © Springer-Verlag 2007
The Symbolics of Death and the Construction of Christian Asceticism: Greek Patristic Voices from the Fourth through Seventh Centuries
No full textThis thesis examines the role which death plays in the development of a uniquely Christian identity in John Climacus’ seventh-century work, the Ladder of Divine Ascent and the Greek ascetic literature of the previous centuries. I argue that John Climacus deploys language of death, inherited from a range of Greek Christian literature, as the symbolic framework within which he describes the ascetic lifestyle as developing a Christian identity. This framework is expressed by thee ascetic practice of ‘memory of death’ and by practices of renunciation described as ‘death’ to oneself and others.
In order to understand Climacus’ unique achievement in regard to engagement with death it is necessary first to situate the Ladder and its author within the literature of the Greek ascetic tradition, within which Climacus consciously wrote. In the Introduction I develp ways Climacus draws on and develops traditional material, while arguing that it must be treated and interpreted in its own right and not simply as his ‘sources.’ I then examine the vocabulary of death and the lines of thought opened up in the New Testament. Chapter One argues that the memory of death plays an important role in Athanasius’ Vita Antonii. Chapter Two surveys material from the fifth- and sixth-century Egyptian and Palestinian deserts in which memory and practice of death are deployed in a wider variety of ways and are increasingly connected to ascetics’ fundamental understanding of self and salvation. Chapter Three examines the sixth-century Quaestiones et Responsiones of Barsanuphius and John of Gaza in which further elaboration of the same thematic is discernible. Chapter Four concludes this thesis with a sustained reading of John Climacus’ Scala Paradisi in which the various thematics centring on memory and practice of death are synthesized into the existential framework and practical response, respectively
VEGF levels in the aqueous humor of patients with primary open angle glaucoma: A systematic review and a meta-analysis
No full textPurpose: To compare the VEGF levels in the aqueous humor of patients with Primary Open Angle Glaucoma (POAG) and non-glaucomatous eyes and reveal any potential statistically significant correlations. Methods: We searched PubMed, from inception to December 31, 2021. Key search terms included VEGF and Glaucoma. All relevant studies that evaluated the VEGF levels in patients with POAG and in the control group were included in this systematic review. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis of Diagnostic Test Accuracy Studies (PRISMA-DTA) guidelines were followed. Data were extracted independently by 2 authors. Heterogeneity was statistically quantified by Q, H, and I2 statistics, and a meta-analysis was performed using the random-effects model. Results: Seven cross-sectional studies were included in the meta-analysis. 144 eyes were enrolled in the POAG group and 162 eyes in the control group. The random effect model showed no statistically significant difference between the two groups (SMD =0.284, 95% CI = -0.173 to 0.741; P = 0.223), but we noticed a trend towards elevated VEGF levels in the aqueous humor of POAG patients. Significant heterogeneity was detected (I2= 74.1%, P = 0.001). Conclusions: This systematic review and meta-analysis indicates a trend towards elevated VEGF-A levels in the aqueous humor of patients with POAG and suggests a potential neuroprotective role of VEGF in patients with POAG. Future studies are required to evaluate the exact role of VEGF in POAG. © The Author(s) 2023
Les études néohelléniques en Espagne
No full textThis article gives a historical overview of the relationships developed between the Iberian Peninsula and Byzantine Greece since the MiddleAges. The author also highlights the Spanish interest in the Greek world during the Ottoman Empire. The current situation of modern Greek studies in Spain follows. The author describes a lively yet fragile field of study. He believes that the result of current efforts will depend on careful choices and coordination. He calls upon the Greek state to play a crucial role therein.This article gives a historical overview of the relationships developed between the Iberian Peninsula and Byzantine Greece since the MiddleAges. The author also highlights the Spanish interest in the Greek world during the Ottoman Empire. The current situation of modern Greek studies in Spain follows. The author describes a lively yet fragile field of study. He believes that the result of current efforts will depend on careful choices and coordination. He calls upon the Greek state to play a crucial role therein.L’auteur présente un aperçu historique de relations développées depuis le Moyen-Age entre la péninsule Ibérique et le monde grec de Byzance, ainsi que l’intérêt des Espagnols pour le monde grec durant la période de l’occupation ottomane. Il présente par la suite la situation actuelle des études néohelléniques en Espagne, un portrait vivant mais fragile, comme il le laisse lui-même entendre.En effet, l’auteur pense que le resultat des efforts actuels pour développer les études néohelléniques dépendra des choix judicieux et de la coordination de mouvements et estime que l’Etat grec est appelé à y jouer un rôle crucial
Nonorganic visual loss in a child due to school bullying
No full textPurpose To describe a case of a child with nonorganic visual loss due to school bullying. Observations An eight-year-old boy presented with bilateral painless vision loss for a few days. His best corrected visual acuity (BCVA) was 20/200 in the right eye and 20/140 in the left eye. Color vision was normal. Fundoscopy, visual fields, electroretinography, electrooculography and visual evoked potentials were within normal limits. A nonorganic (psychogenic) cause of visual loss was suspected. A conversation with his parents and school teachers revealed that he was undergoing intense school bullying. Discussion between the boy and his parents and teachers' awareness helped in relieving the boy's stress. After two weeks BCVA was 20/20 bilaterally. Conclusions and importance School bullying is a potential cause of nonorganic vision loss in children. Correct diagnosis, and support by the parents and teachers might rapidly alleviate the symptoms. © 2017 The Author
Jubilee, Μelchizedek and the Epistle to the Hebrews: a contribution to the formation of christian soteriology
No full textThe study breaks down into two parts, comprising six chapters. There is also an introduction before Part I and after the final chapter of the book a few pages are devoted to the conclusions.Part Ι (chs. 1-3) is entitled “Jubilee year and Melchizedek in the pre-Christian era” and includes three chapters exploring the two basic aspects of the study (jubilee and Melchizedek) from their beginning to the New Testament period. Part ΙΙ (chs. 4-6) has the title “Jubilee year and Melchizedek in the Christian era” and includes three chapters, the first from which is devoted to the survey of the presentation of the jubilee in the writings of the New Testament and the other two have been focused in the epistle to the Hebrews. The “Introduction” of the work surveys the New Testament view of salvation or in other words, the way by which the New Testament authors understand the meaning of salvation in connection or not with the death of Christ. Then, the overall problem of the remission of sins in the New Testament is explored as is presented in its three conceptions. This work chose to explore the third one, the interpersonal remission of sins. “Jubilee year” is the theme of Chapter 1 that surveys essentially the origin and the development of the jubilee year, but also the presence of analogous social institutions in Near East during the ancient times. Here, jubilee is analyzed in direct relation with the Sabbath day and the sabbatical year. By this way of survey the confusion that occurs often because of the provisions of the sabbatical and the jubilee year is resolved, since the features of each institution are reported with an indicative method and the relative verses from Lev 25 are analyzed. In the units of this chapter are explored issues that have to do with the laws of the jubilee, etymology, calendar, origin and date of Lev 25. In the last unit there is an intercultural survey of analogous institutions of social justice in Mesopotamia, Syria, Egypt, Greece, Rome, etc. From this survey arise very important social aspects that occur in the case of the remission of sins in the New Testament. Chapter 2 is entitled “The wholistic presentation of the jubilee year”. This chapter deals with the social, ritual and theological features of the jubilee. This analysis comprises the necessary presupposition in order to interpret correctly the influence of this institution to the understanding of the remission of sins in the New Testament. Firstly, there is a presentation of the conclusions of modern research about the social stratification of the Jewish society in a broader period of its history, from the era before the monarchy up to the return of the Babylonian exile, while then, Israel’s agrarian economy and method of production is presented in order to reveal the daily way of life, social and economic relations of the people and the problems that involved the destruction of the production and the bankruptcy. What follows are the ritual features of the jubilee. This unit comprises the necessary presupposition in order to interpret correctly the relation of jubilee with the Day of Atonement for a wholistic understanding of the remission. With a historical and ritual flashback to the New Year’s Day, Day of Atonement and the festival of Booths the ritual aspects that are contained in the provisions of the jubilee are displayed. The survey continues with the theological features of the jubilee. Land ownership, liberation from the enslavement of Egypt and the institution of the covenant has been chosen as the three basic theological axes that determine the life of the Jewish community in direct relation with Yahweh. The last two units are an attempt of quest references that are connected with sabbatical and jubilee year in the whole Old Testament and the intertestamental literature. Jubilee year was changed from a social institution to an eschatological symbol that was expected by the people and was related with the final salvation. The conclusion here is that the jubilee which was a responsibility of the people of God became a future interposition of Yahweh or his messiah. Chapter 3 has the title “Τhe mysterious figure of Melchizedek”. Here the survey of the figure and the role of Melchizedek are displayed through the intertextual analysis. This chapter explores firstly Melchizedek in the Old Testament, Pseudepigrapha, Dead Sea Scrolls, where we focused mainly on 11QMelch, because is a key text as it relates explicitly Melchizedek with the Jubilee year. The above exploration is being continued with Melchizedek in Philo and Josephus, because these writers represent ideas about the figure of Melchizedek during the first century C.E. The aim here is to observe what ideas could be possible known to the author of Hebrews who writes at the same period. We conclude that there were two different ideas about Melchizedek that were maintained also during the later centuries. The first tradition, obviously the premier one, views Melchizedek as a historical person. According to this view, the mysterious Melchizedek is illustrated as king-priest of Salem. The second tradition presents Melchizedek as a heavenly or angelic being and occurs in the Dead Sea Scrolls. Chapter 4, “Ιndirect references and allusions to the jubilee year in the Νew Τestament”, surveys mainly the way by which the image of the jubilee has been used by the several authors of New Testament books. Although we observed that there is not an explicit reference, several allusions and references to the provisions of jubilee occur in the text that are related with themes such as the remission of sins and salvation. The first category of texts includes passages where the provisions of the jubilee have been used mainly by the authors of the Synoptic Gospels into the way of the interpersonal remission of sins. The second category includes passages where the ideal of the social restoration is related with the coming of Jesus and the establishment of the Kingdom of God. To conclude, in the first category of texts the remission of sins happens spontaneously, because it depends on humans’ social relation and interaction and so it is not related with the death of Jesus or the faith to him. In the second category of texts the same way of interaction between God and people is presented too, but here the coming of Jesus interplays a determinative role. We observed an impressive absence of this motive in the undisputed Pauline epistles. In the first case a more frequent use of the motive is being observed in the Gospel of Matthew and follows the Gospel of Luke, while in the second case occurs the reverse. Chapter 5 is entitled “Direct references to Melchizedek in the New Testament. The epistle to the Hebrews”. After the presentation of a historical and theological flashback of the previous research in the epistle to the Hebrews, the chapter discusses the theological ideas that occur from the whole of the New Testament only in Hebrews. Finally, there is a brief survey of the ideological background of the epistle, while the figure of Melchizedek is presented analytically under the focus of modern hermeneutics. Based on all the above issues we tried then to analyze the broader unit Heb 5:1-7:28. The interpretation of Heb 5:1-7:28 is divided into four subunits (5:1-10; 5:11-6:20;7:1-10 and 7:11-28).Chapter 6 has the title “Jubilee year, Melchizedek and salvation”. In the final chapter of the study we tried to evaluate the data from Hebrews about the presence of Melchizedek and jubilee year. Based on the Midrash on Melchizedek (11QMelch) we observed similarities and differences with Hebrews and especially with its soteriological views. In the first unit of the chapter features about the Melchizedek traditions that the author of Hebrews is aware about are described and the reason of Melchizedek’s choice is estimated. In the next pages what follows is a survey for the presence of a jubilary terminology within the text and this is supported that occurs in Heb 3:7-4:11. The survey goes on with the presentation of several redemptive figures with a role parallel to that of heavenly Melchizedek. Through the intertextual approach we analyzed several texts in which the role of the messiah appears similarities with that of Melchizedek in 11QMelch. These texts are: Testament of Levi, Aramaic Apocalypse, 4QCatenaa and Messianic Apocalypse. This survey follows the continuity of the tradition that attributes a redemptive role to the heavenly Melchizedek in later Gnostic texts (NHC IX,1, 2 Ieū, Pistis Sophia) and 2 Enoch. We concluded that although new features have been added in these views about Melchizedek, the basic tradition is the old Judaic one which is originated from 11QMelch.The presentation of texts continues in the next unit too, where the analysis is restricted now to those texts that relate the jubilee year with the expected liberator. Based to this category of texts we concluded that this relation was part of a particular Judaic tradition, which in the theological production of the Qumran community had taken a special importance. Signs of this tradition occur in the New Testament too. We think that every writer of the particular texts that we examined related the period of salvation with the messianic figure he wants, attributing to him acts that are related with the jubilee year. The chapter is concluded with a reference to the soteriological role of Christ in Hebrews and of Melchizedek in 11QMelch and to the contribution of Hebrews to the formation of Christian soteriology. Special focus has been added to issues such as high priesthood, judgement and salvation that appear similar to both texts. Beside this, we observed also a different presentation of Melchizedek in the two texts and the emergence of the only soteriological figure in Hebrews that is not other from Christ, the new high priest. Very important is the conclusion that what is said in 11QMelch illuminates several issues that in Hebrews just occur without further explanation. The jubilary terminology is also present in the text of the epistle with the broader meaning of Sabbath rest (4:9). Two motives appear in Hebrews that are related with the salvation of the believers, but have a different direction. The first one has a horizontal eschatological perspective and is related with the Sabbath rest that still remains for the people of God. The second, in anticipation, is a christological one, has a vertical perspective and is related with the once for all sacrifice of Christ for the salvation of people. This has to do with the problem that theological process had to overcome within the ancient Christian community and was not other than the death of Christ. The author of Hebrews tried to correct theologia gloriae through a theologia crucis in order to determine to his readers the figure and the work of their liberator. The last pages of the book are devoted to the “conclusions” of this study. We summarize them below:1. It is obvious that the issue of the remission of sins and mainly the way it happens in a few but efficient amounts of occurrences in the New Testament without any expiatory reference, it comes from the worldview of the jubilee year. On the other way, Paul’s theologia crucis functions catalytically into his undisputed epistles and it doesn’t leave any place for a jubilary way of remission of sins.2. The author of Hebrews is aware of both traditions about Melchizedek. Although a direct relation between the author of Hebrews and the Midrash on Melchizedek is not possible to be supported, it seems that some ideas that occurred in the document from the Dead Sea illustrate many analogous ideas which in Hebrews are only mentioned without explanation.3. A jubilary understanding of salvation is observed by the use of the idea of Sabbath rest that still remains for the Christian community to which the epistle to the Hebrews is addressed. The problems that the text report are not irrelevant with the presence of the King of Righteousness. Though, the idea of the expectance of the future salvation has a parenetic purpose: to proclaim its fulfilment in both social and spiritual level.Οι διατάξεις του ιωβηλαίου έτους και το κοσμοείδωλο που ο συγκεκριμένος θεσμός οραματιζόταν σχετικά με την κοινωνική και θρησκευτική αποκατάσταση συνθέτουν στο χώρο της ερμηνείας της Αγίας Γραφής μια ομιχλώδη εικόνα που εδώ και καιρό ζητά απεγνωσμένα να ξεκαθαρισθεί. Από την άλλη, εξίσου ομιχλώδης είναι και η παρουσία της μυστηριώδους προσωπικότητας του Μελχισεδέκ, ο οποίος στη γραφίδα των βιβλικών συγγραφέων εμφανίζεται από το πουθενά και εξαφανίζεται αμέσως μόλις ολοκληρώσει το έργο του. Στην παρούσα μελέτη επιχειρούμε να ξεδιαλύνουμε το τοπίο γύρω από το μυστήριο που περιβάλλει το θεσμό του ιωβηλαίου έτους και την προσωπικότητα του Μελχισεδέκ, να εξετάσουμε βήμα προς βήμα την εξέλιξη του ρόλου τους για τη σωτηρία του λαού του Θεού και να εξηγήσουμε τον όποιο συνδυασμό τους σε εξωβιβλικά αλλά και πιθανώς καινοδιαθηκικά κείμενα. Στην παρατήρηση ότι η προς Εβραίους επιστολή διακρίνεται από τα υπόλοιπα βιβλία της Κ.Δ. εξαιτίας της ιδιόμορφης θεολογικής της διδασκαλίας, αλλά και της εξάρτησής της από την Π.Δ. προστίθεται και το γεγονός ότι διασώζει την εκτενέστερη αναφορά στον Μελχισεδέκ στην Αγία Γραφή. Μετά την καθιέρωση στη σύγχρονη βιβλική έρευνα της νέας εικόνας του Μελχισεδέκ με βάση τα δημοσιευμένα χειρόγραφα του Κουμράν, όπου και εντοπίζεται ένας συνδυασμός του λυτρωτικού ρόλου του ουράνιου πλέον Μελχισεδέκ με το εσχατολογικό ιωβηλαίο που θα σημάνει τη σωτηρία του λαού του Θεού, η πρόκληση για την αναψηλάφηση των απαρχών της χριστιανικής σωτηριολογίας ήταν αναπόφευκτη. Κατά συνέπεια, η αναζήτηση της σύνδεσης αυτής της σχέσεως με την προς Εβραίους επιστολή, ενός δηλαδή κειμένου που διαδραμάτισε σημαντικό ρόλο στη ιστορία της Εκκλησίας για την τελική διαμόρφωση του χριστολογικού προβλήματος, αλλά και της λειτουργικής της ζωής ιδιαίτερα στην Ανατολή, απαιτεί κριτική επιστημονική ανάλυση για τη διαλεύκανση της μοναδικής σωτηριολογικής θέσεως αυτού του κειμένου απέναντι στο γεγονός «Χριστός»
