125 research outputs found
Consistency of performance of a new craniostat for oblique lateral transcranial radiographs of the temporomandibular joint
No full textA new craniostat for use with OLTP radiography of the TMJ is described. In a clinical study of 20 patients the craniostat demonstrated a satisfactory consistency of radiographic reproduction
Herpes simplex virus type 1 in periapical pathoses. Systematic review and meta‐analysis
No full textObjectives: The objective of this systematic review and meta-analysis of observational studies was to assess whether herpes simplex virus type 1 (HSV-1) can infect endodontic periapical lesions.
Materials and methods: Studies with cross-sectional design investigating HSV-1 in periapical tissues of patients with symptomatic and asymptomatic acute and chronic apical periodontitis were searched through MEDLINE, Scopus, Embase, Web of Science, and Google Scholar. Pooled HSV-1 prevalence proportion with 95% confidence interval (95CI) in periapical lesions was assessed with both fixed-effect and random-effects models, with/without adjustment for study quality and publication bias. Result robustness was investigated through sensitivity and subgroup analyses.
Results: Literature search, performed twice, provided 84 items, and eight remained for the meta-analysis; globally, there were 194 patients mostly adults. The pooled HSV-1 prevalence proportions, assessed with various methods, were 6.9% (95CI, 3.8-11.3%, fixed-effect); 6.8% (95CI, 3.6-11.0%, random-effects); 8.1% (95CI, 4.4-14.5%, quality-adjusted); and 4.8% (95CI, 2.0-11.4%; adjusted for small-study effect).
Conclusions: The results indicated that HSV-1 can colonize the periapical tissues of 3%-11% patients with periapical diseases. Such data do not imply a causative role of HSV-1 in disease development and advancement. Well-designed and large-sized prospective cohort studies should be added in the literature panorama
Changing epidemiology of HCV infection in patient with oral lichen planus in North-West Italy
No full textoral lichen planus (OLP) is a chronic inflammatory condition, affecting roughly 1.5-2% of the total population, women almost more than twice as men; patients of all ages could be interested, more frequently in the fifth to sixth decades of life (Arduino, 2017). This article is protected by copyright. All rights reserved
Herpes simplex virus type 1 in subgingival plaque and periodontal diseases. Meta‐analysis of observational studies
No full textAbstract
Background and objectives: This meta-analysis
of observational studies (PROSPERO
registration number CRD42021236054) sought to investigate strength and generalizability
of the association of herpes simplex virus type 1 (HSV-1)
in subjects
with plaque-induced
gingivitis and periodontitis, since the data from literature are
contrasting.
Material and methods: Case–control
and cross-sectional
studies, investigating HSV-1
in subgingival plaque/crevicular fluid and periodontal status, were searched through
MEDLINE via PubMed, Scopus, Web of Science and Google Scholar. From each study
the crude odds ratio (OR) with 95% confidence interval (95CI) was extracted, and the
pooled OR was assessed for periodontitis, chronic and aggressive, and gingivitis. The
meta-analytic
method was chosen based on the level of heterogeneity. The generalizability
of results, determined by the meta-analysis
bias, was investigated through
secondary analyses including sensitivity analyses for study quality, publication bias,
and study inclusion, and subgroup analyses for quality of scientific journals that published
the primary studies, world Region, subgingival plaque sampling method and
study design.
Results: Twelve studies were included (738 cases, 551 controls). The pooled ORs were
4.4 (95CI, 1.9–10.2)
for any periodontitis; specifically, 2.8 (95CI, 1.0–8.3)
for chronic
periodontitis, 11.8 (95CI, 5.4–25.8)
for aggressive periodontitis and 4.8 (95CI, 2.1–11.0)
for gingivitis. These estimates were statistically significant, excluding for chronic
periodontitis, resulting marginally significant (p = .05). Secondary analyses on any and
aggressive periodontitis, and, partly, chronic periodontitis corroborated the results,
while the material was insufficient for secondary analyses on gingivitis.
Conclusions: The results obtained indicated that HSV-1
is associated with periodontitis,
while data about gingivitis are inconclusive. HSV-1
investigation in subgingival
plaque could help assess periodontitis risk and severity and, if causal association were
confirmed, could contribute to its control
A randomized pilot study to assess the safety and the value of low-level laser therapy versus clonazepam in patients with burning mouth syndrome
No full textManagement of Oral Hydroxyurea-Related Ulcers: A Cases Series
No full textHydroxyurea (HU) is an anti-cancer agent commonly used in myeloproliferative Philadelphia negative disorders as polycythemia vera (PV), essential thrombocitosis (ET) and myelofibrosis (MF). [...
Treatment of angular cheilitis: a narrative review and authors' clinical experience
No full textAngular cheilitis (AC) is a clinical entity first described in the XIX century, characterized by erythema, rhagades, ulcerations, and crusting of one or both lip commissures and perilabial skin, responsible of an unpleasant and painful discomfort. Aim of this manuscript was to examine and evaluate the therapeutic options actually available for AC. Despite antifungals being the first-line treatment for most of clinicians, very limited scientific evidence supports their reliability, with just two RCTs published between the '70s and the '80s. Furthermore, alternative topical treatments, various techniques of occlusal vertical dimension restoration, B-vitamin supplementation, anti-drooling prosthetic device and photodynamic therapy have been experimented and proposed, mostly in the form of case reports or case-series on a small number of individuals. Our group found in 1% isoconazole nitrate (ISN) and 0.1% diflucortolone valerate (DFV) ointment the most consistent AC treatment, due to the broad spectrum of ISN against many species of dermatohpytes and bacteria, and the anti-inflammatory properties displayed by DFV. However, further and well-designed trials on larger samples of patients are needed to assess the differential profile of consistency of the treatments outlined in literature and claimed by the Authors of this paper. This article is protected by copyright. All rights reserved
Conservative Approach in Patients with Pemphigus Gingival Vulgaris: A Pilot Study of Five Cases
No full textObjectives. The aim of this pilot study was to describe the clinical efficacy of a conservative oral hygiene protocol in patients affected by gingival pemphigus vulgaris (PV) applied in a case series. Methods. Subjects suffering from PV with gingival localisation and slightly responsive to conventional treatment with systemic corticosteroids and immunosuppressive drugs were selected among individuals treated in the Unit of Oral Medicine Section of the University of Turin. Five subjects received nonsurgical periodontal therapy, over a 7-day period, including oral hygiene instructions; patients were instructed about domiciliary oral hygiene maintenance and instructions were reinforced at each visit and personalised if necessary. Clinical outcome variables were recorded at baseline (before starting) and 16 weeks after intervention, including full mouth plaque score (FMPS), bleeding scores (FMBS), probing pocket depth (PPD), oral pemphigus clinical score (OPCS), and patient related outcomes (visual analogue score of pain). Results. Five patients were treated and, after finishing the proposed therapy protocol, a statistical significant reduction was observed for FMBS (P=0.043) and OPCS (P=0.038). Conclusions. Professional oral hygiene procedures with nonsurgical therapy are related to an improvement of gingival status and a decrease of gingival bleeding in patients affected by PV with specific gingival localization
Impact of a sodium carbonate spray combined with professional oral hygiene procedures in patients with Sjögren's syndrome: an explorative study
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