19 research outputs found
The subzero microbiome: Microbial activity in frozen and thawing soils
No full textMost of the Earth's biosphere is characterized by low temperatures (<5 °C) and cold-adapted microorganisms are widespread. These psychrophiles have evolved a complex range of adaptations of all cellular constituents to counteract the potentially deleterious effects of low kinetic energy environments and the freezing of water. Microbial life continues into the subzero temperature range, and this activity contributes to carbon and nitrogen flux in and out of ecosystems, ultimately affecting global processes. Microbial responses to climate warming and in particular, thawing of frozen soils are not yet well understood although the threat of microbial contribution to positive feedback of carbon flux is substantial. To date, several studies have examined microbial community dynamics in frozen soils and permafrost due to changing environmental conditions, and some have undertaken the complicated task of characterizing microbial functional groups and how their activity changes with changing conditions, either in situ or by isolating and characterizing macromolecules. With increasing temperature and wetter conditions microbial activity of key microbes and subsequent efflux of greenhouse gases also increase. In this review, we aim to provide an overview of microbial activity in seasonally frozen soils and permafrost. With a more detailed understanding of the microbiological activities in these vulnerable soil ecosystems, we can begin to predict and model future expectations for carbon release and climate change.Peer reviewe
Comparison of clinical and radiological outcomes in intertrochanteric fractures treated with InterTAN nail against conventional cephalomedullary nails: a systematic review
No full textIntertrochanteric fractures, accountable for 50% of hip fractures, can be fixed with cephalomedullary devices such as Proximal Femoral Nail Anti-rotation (PFNA™), Gamma3 Nailing System and TRIGEN™ InterTAN™ nail (IT). IT uniquely uses two cephalocervical screws which allow for linear compression and provide additional resistance to femoral head rotation. A literature review assessing clinical outcomes of these devices was conducted, with fourteen studies enrolling 3104 patients meeting the inclusion criteria. PFNA and Gamma3 had better intraoperative outcomes compared with IT, however IT had superior implant-related outcomes of cut-out and screw migration. No difference was found between IT and PFNA or Gamma3 in Harris Hip Scores (HHS), time to union, malunion and non-union. Further long-term studies are needed to evaluate clinical outcomes and cost-effectiveness of cephalomedullary devices
Isolation And Characterization of Pediocin Pa-1 Producing Lactic Acid Bacteria
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
Decentralizing infrastructure : for good or ill?
No full textThe author examines the many faces of infrastructure decentralization: the costs and benefits, the government structure (constraint or variable?), the"polycentric"approach, and how to make decentralization work (for whom?). He proposes basic principles and guidelines for policy design, for both small projects and large. Broadly, these guidelines are summed up in a few propositions. In all countries, some critical infrastructure is provided through a decentralized political structure. Current trends make that likely to be more true in the future. Decentralization, however defined, in and of itself had no necessary implications for good or evil so far as infrastructure is concerned: its effects depend on the incentives various decisionmakers face. The key to ensuring that these incentives are conducive to"good"decisions (about design, siting, timing, finance, pricing, operation, maintenance, and use of infrastructure) is to ensure that those who made the decisions bear the financial (and political) consequences, as much as possible. Politically, this means that political leaders at all levels should be responsive and responsible to their constituents, and that those constituents are fully informed about the consequences of all decisions. Making politicians bear the consequences of their own mistakes is as close as one can get to a"hard"political budget constraint. Economically, it must be difficult for local residents to shift cost to nonresidents who do not receive benefits and to make local decisionmakers fully responsible to their citizens for the use they make of revenues collected from them (through local taxes), to users of infrastructure (local or otherwise) for the use made of the revenues they contribute (through user charges of various sorts), and to taxpayers in general for the use made of any transfers (or subsidized loans) they receive. Administratively, what such a system requires is a clear set of"framework"laws (on local budgeting, financial reporting, taxation, contracting, dispute settlement, rules to be followed in designing user charges and so on), as well as adequate institutional support for localities to operate in this environment. To the extent that these conditions are not met, the perverse incentives that too often exist because of the structure and finance of the public sector in many countries will probably be exacerbated by the current tendency to decentralize more and more decisions in the public sector.National Governance,Banks&Banking Reform,Municipal Financial Management,Public Sector Economics&Finance,Economic Theory&Research
Disrupting Monocultural Tendencies through Multimodal Montage
No full textThis thesis contends with the pervasive impact of monocultural tendencies as manifested in the political, cultural, and media landscapes of contemporary India, particularly focusing on the unfolding context of 2024. Amidst an intensifying crisis marked by polarization, historical erasure, and the rise of hegemonic nationalism, this thesis posits art, particularly through the framework of `multi-modal montage,' as a agent of political disruption for `redistributing the sensible.' Tracing the aesthetic and political evolution of montage from its early 20th-century origins in Soviet cinema to its contemporary forms, the thesis outlines the transition from montage defined by collision and conflict to the soft, spatial, and interactive practices of figures such as Nam June Paik and Harun Farocki. It further investigates how `surface tension' and `unquiet objects' manifest within the multi-modal montage in the works of artists like Nalini Malani, Krzysztof Wodiczko, Shilpa Gupta and Nida Sinnokrot.
As an Indian artist, the author situates her own practice within this discourse, highlighting projects such as `The Whistleblower' (2023), a tangible archive within an everyday object, and `A Mystery for You' (2023-24), a fact-checking game that merges a tangible interface with a large language model (LLM). These works exemplify the thesis's argument that artistic interventions can critically challenge and reframe dominant sociopolitical narratives, offering new perspectives and resistances against the monocultural hegemonies. Extending this analysis, the author discusses her exhibition 'Forensic Artifacts of a Democracy in Crisis' (2023) as an operative space. Through a curated assemblage of works, the exhibition provided a physical space for interaction, reflection, and conversation, enabling audiences to engage with the themes of the thesis viscerally. In all, this thesis argues for the critical role of art in challenging memory and forgetting, from fabricated histories to the fall and rise of monuments. From the polarization of media to the flattening of identities, of echo-chambers and absences and grand narratives.S.M
Peer victimization and substance use in early adolescence: longitudinal analyses of risk and protective factors
No full textThis dissertation uses socio-ecological and transactional frameworks (Bronfenbrenner, 1977; Espelage & Swearer, 2003; Sameroff & Chandler, 1975) to examine how variables in adolescents’ individual, family, and peer contexts interact to predict, and prevent, peer victimization and subsequent substance use. Through a series of analyses the dissertation examines risk and protective factors including depression and self-esteem (individual ecology); family conflict and family closeness (family ecology); and association with delinquent peers and peer social support (peer ecology). These variables are hypothesized to have mediating and moderating roles in the association between peer victimization and substance use. These questions are examined as a secondary data analysis using longitudinal data collected at four time points over a period of two years in a diverse (49% female, 51% Black, 34% Caucasian) middle school sample of 1132 early adolescents. Longitudinal structural equation modeling was used the primary data analytic technique. A transactional association was found between peer victimization and substance use. Additionally, all the variables examined significantly influenced the relation between peer victimization and substance use. Depression, self-esteem, family conflict, and peer social support were found to have meditational associations with peer victimization and substance use. Family closeness and affiliation with delinquent peers was found to moderate the association between peer victimization and substance use. The implications of these findings and potential points of intervention and prevention are discussed.Item withdrawn by Mark Zulauf ([email protected]) on 2013-07-08T18:57:03Z
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Reclaiming Humanity, Removed in Space and Time: Rabindranath Tagore’s “Letter Renouncing Knighthood” in 1919 British India
No full textOn April 13th, 1919, the British General Reginald E. Dyer ordered his troops to open fire on an unarmed crowd of Indian civilians who had gathered that morning in Jallianwala Bagh, Amritsar, for a religious celebration. Hundreds of men, women, and children were killed while others were thrown into a well to escape being shot, buried under their dying relatives’ bodies, or left gravely wounded or orphaned. Dyer would soon be celebrated by many Britons as a “saviour” for teaching these Amritsar residents, as well as the rest of British India, a salutary “lesson” not to question Britain’s colonial might (Sayer 143, 161-2). Devastation permeated India as the news of the massacre and of Britain’s callous response to it spread across the nation (Pedersen).
I still remember these details, printed in the fine black print of a history textbook I had borrowed from my third-grade classroom in New Delhi, India, early in 2010.1 Reading of the Amritsar massacre is seared into my memory as one of the first times I vividly recall feeling terror from an encounter with history. It was, indeed, seared into the collective memory of Indians in 1919 who were shocked at the brutalization and dehumanization inflicted upon them under British colonial rule. How does one respond to an event that is so horrific—an event that dehumanizes one’s people—while removed in space, as other Indians were outside Amritsar, or in time, as I was nearly a century later?
The Bengali poet and Nobel Laureate in Literature Rabindranath Tagore was among those grappling with this question in the summer of 1919. English-educated Indians such as Tagore formed an elite minority in early 20th Century British India, which had historically distanced itself from India’s masses to seem as "British" as possible in order to win favors from the colonial government (Mukherjee 30-31). Located in Calcutta, far from Amritsar on the opposite side of British, Tagore seemed spatially and socially removed from the massacre. Yet in May 1919, he penned a letter to the British Viceroy expressing his dismay and renouncing his knighthood—granted in 1915 after he received the Nobel prize—to stand in solidarity with all of India.2 Tagore’s project seems clear: to re-claim Indians’ humanity after “a degradation not fit for human beings” (Tagore). However, the form of Tagore’s letter seems to be in tension with this project, for he did not divorce himself from "British-ness" to formulate his claims. Rather, Tagore used the language of the very state he is condemning—writing in English—and maintained deference to British authority by describing the “honour” of meeting “His Majesty the King” and his “admiration” for the previous Viceroy.3 How can Tagore’s fundamental grievances against the British colonial state be reconciled with his dignifying of these British institutions?
In order to examine how Tagore establishes these grievances and to conceptualize his sense of dismay, one might turn to American journalist Alisa Solomon’s lecture, “Who Gets to Be Human on the Evening News.” Solomon argues that journalism can “confer humanity on some subjects . . . and not on others” (1587). Specifically critiquing Western news coverage of Palestine, she emphasizes how, through “framing” Palestinian subjects without context for their experiences, “the humanity of Palestinians is thrown into question” (1589-1590). Tagore’s letter reveals his awareness of how similar British media narratives dehumanized Indians. Poignantly, he condemns the “callousness” of British media, pointing out that Dyer’s actions were
praised by most of the Anglo-Indian papers, which have in some cases gone to the brutal length of making fun of our sufferings . . . smothering every cry of pain and expression of judgement from the organs representing the sufferers. (Tagore)4
Tagore’s emphasis on how “organs representing the sufferers” have been “smother[ed]” parallels Solomon’s critiques of portrayals of Palestinians in the 2000s. By denying Indians the opportunity to voice their “pain” and “judgement,” as Tagore observes, the British media trivialized Indians’ context of the massacre and made their anti-colonial response seem unjustified—just as Solomon argued that Palestinian resistance seemed “incorrigible” because the Western media “erase[d]” their context of “[Israeli] occupation” (Tagore; Solomon 1589). Notice also the physical connotations of Tagore’s language—“brutal,” “sufferings,” “smothering,” and “organs”—when describing the actions of “the Anglo-Indian papers.” This language alludes to the massacre’s grave physical reality, distorted by the media, of bodies “smothered,” “organs” destroyed, “brutal[ity]” inflicted, and human “suffering.” In turn, one perceives Solomon’s arguments that de-contextualized media coverage is not simply ill-informed, but explicitly dehumanizing: in Tagore’s portrayal, these papers inflict figurative violence on all “our” (i.e. Indian) bodies in their mockery of the massacre’s victims.
Tagore, however, seems also to transcend Solomon’s arguments, shifting from condemning decontextualized media narratives to inverting these narratives to dehumanize the British colonial regime. “Such treatment,” declares Tagore, “has been meted out to a population, disarmed and resourceless, by a power which has the most terribly efficient organization for destruction of human lives.” The alliterated “p” in this line juxtaposes the “population” of Indians with the “power” of Britain. Upon the Indians, Tagore confers humanity, expressing their tragic context of being “disarmed and resourceless.” The British, in contrast, become machine-like, an enemy to humanity, using their powerful “organization” to destroy “human lives.” Tagore does not offer any context for Dyer’s actions, asserting that “it [the “power”] can claim no political expediency, far less moral justification” for the massacre—i.e., that no such context exists. The force of these words can be measured in Solomon’s own arguments: “acting rationally . . . distinguishes human beings from brutes,” so when a social group is presented irrationally, as Britons are in Tagore’s letter, they appear less than human (1588). Thus, as Tagore lays out his grievances against Britain, he presents the massacre’s consequences not only for the Indian masses, who were enduring violence, but also for the British colonial state, who, in his eyes, was losing its humanity.5
When his condemnation of Britain was so fundamental, one might question the form of Tagore’s letter: why would he choose to write in English rather than his native Bengali? The arguments presented by American philosopher Martha Nussbaum, in her essay “Compassion & Terror,” may offer some insight into this question. Nussbaum cites the Ancient Greek play The Trojan Women as an example where its Greek author, Euripides, “invited [his] [Greek] audience” to feel “compassion for the women of Troy” who had been enslaved, and whose men were massacred, by Greek forces in the Trojan war (11). She moves, however, to acknowledge the paradoxical form of this play: Euripides evokes compassion for the Trojan women by making them seem Greek, allowing for the audience to conclude “they are just us, and we are the ones who suffer humanly,” so they must too (Nussbaum 11). Within this framing, Tagore seems to take on Euripides’ role of translating Indian humanity into terms a British audience could understand, writing,
The disproportionate severity of the punishments inflicted on the unfortunate people and the methods of carrying them out, we are convinced, are without parallel in the history of civilized government.
Tagore’s probing use of the word “civilized” evokes the British conception of themselves as a civilization—a notion grounded in the idea that Britons did not wantonly or barbarically kill other human beings and were indeed "liberating" their colonized non-European subjects from such despotic treatment.6 By invoking this familiar concept, Tagore urged the reader to extend their sense of civilization to encompass the lives of “the unfortunate people” of Amritsar who had been brutally killed. His decision to write in English, a language that all Britons could understand, strengthens this exhortation: he could address British society at large, not solely the Viceroy. Thus, the form of his letter evidently enables him to reach what Nussbaum would describe as the “narrow” and “self-serving” “sense of compassion” all humans possess, using the English language and concept of “civilized government,” so central to Britain’s sense of national identity, to appeal to Britons’ compassion (Nussbaum 11).
However, there is a crucial difference between Tagore’s position and what Nussbaum imagines to be Euripides’ role. Euripides was Greek, not Trojan, while Tagore was Indian, not British—the former from the society that had inflicted violence, and the latter from the society that had experienced it. Thus, unlike in the case of Euripides, the dehumanization Tagore was writing of reached him, too, suggesting that his appeal to the reader’s compassion transcended Nussbaum’s Western-centric analysis because it involved his own vulnerability. This is reflected in Tagore’s use of the collective subject “we” in the phrases “we are convinced” and “we must strongly assert.” There is something radical about Tagore’s repeated decision to use “we” rather than the individual “I”: he speaks for, and identifies with, the entirety of India, breaking from the tradition of elite Indians segregating themselves from the masses. Tagore’s use of the English language takes on a new significance within this context. By 1919, English was not only a British language but also a colonial one, for elite Indians could also access Tagore’s letter by virtue of their English education. Tagore’s repeated “we” thus becomes an exhortation to his own social class’ compassion, urging them to question their proximity to "British-ness" by illuminating how Britain’s massacre threatened their humanity, too: if even he, with all his distinctions, was part of this “we,” then so were they. By placing his humanity on the line along with that of “the unfortunate people” who died in Amritsar, in terms that Britons and elite Indians alike would understand, Tagore thus extends Nussbaum’s arguments to seek compassion not for “the other,” but for his own society.
It is in these references to his own position, and exhortations to other elite Indians, that we see the culmination of Tagore’s reclamation of humanity. The American theorist Judith Butler’s address, “Bodies in Alliance and the Politics of the Street,” elucidates this aspect of his letter, for she argues that “the body” whose presence “is being actively . . . destroyed by military force” should, in tandem with other bodies, enter “the space of appearance” (a phrase she adopts from Hannah Arendt), forming “a new alliance” (6-7). In the final lines of his letter, Tagore seems to present himself as one such body under threat, forming an “alliance” to reclaim humanity in a manner analogous to Butler’s vision:
Knowing that our appeals have been in vain and that the passion for vengeance is blinding the . . . vision of our Government . . . the very least I can do for my country is to take all consequences upon myself in giving voice to the protest of the millions of my countrymen. (Tagore)
Tagore first establishes the “force” that threatened him—“the passion for vengeance” taking over the colonial government—revealing to him the “helplessness” of his “position” in British India. Though physically unscathed by Dyer’s “military force” himself, Tagore exposes the massacre to be part of a larger structure that was systematically dehumanizing Indians. This leaves his body, as that of a colonial “subject,” as vulnerable to abuse in the public arena as the body of “a transgendered person” “walk[ing] on the street” in Butler’s essay (13). Tagore then seems to consciously enter a public “alliance” with the other bodies under "threat”( to use Butler's words) by describing this letter as “the very least I can do” “to giv[e] voice.” Tagore might not have marched in public, as Butler envisioned, yet in the act of writing this letter he seems to achieve the same end. He attunes himself to other subjugated bodies, capturing the violence and brutalization that had shocked Indians well beyond Amritsar. He also claims an intellectual “space of appearance” (that is, a space of ideas surrounding civilization and humanity) that had long been dominated exclusively by the West: in his inversion of British media narratives and appeals to British compassion, Tagore’s “alliance” of Indians extends and re-conceptualizes this space to include colonized peoples.
The effects of forming such an alliance are profoundly important for Tagore’s desire to reclaim Indians’ humanity. Butler argues that the alliance confers humanity upon each “body,” for “no human can be human without acting in concert with others and on conditions of equality” (9). Tagore seems cognizant of this need to be allied, on equal terms, as he finally explained his decision to renounce the knighthood:
The time has come when badges of honour make our shame glaring in their incongruous context of humiliation, and I for my part wish to stand, shorn of all distinctions, by the side of those of my countrymen, who, for their so-called insignificance, are liable to suffer a degradation not fit for human beings.
The juxtaposition of the personal “I” and third-person “their” affirms Tagore’s awareness of his privileged social standing; “distinctions” such as the knighthood had separated him from his “countrymen,” including those slaughtered by Dyer’s troops. By renouncing the knighthood, Tagore sought to close this distance, creating the “conditions of equality” that Butler described. In his unique historical context, Tagore appears to extend Butler's concept of an equal alliance by implicitly urging fellow English-speaking Indians to join. To them, his bitter mention of “[the masses’] so-called insignificance” must have been particularly visceral: within the colonial state, they had often been positioned to trivialize the Indian masses while seeking “distinctions,” upholding a punishing social hierarchy that encouraged dehumanization and enabled this atrocity even as it promised them illusory political gains. It is as if Tagore sought to shock them out of their blindness, asserting that without an alliance affirming all Indian lives, no individual Indian would be treated as a full “human bein[g]” free from the threat of violence.
At its core, Tagore’s letter serves as a stunning vindication of Indians’ humanity, persisting in spite of this colonial atrocity. When the letter is placed in conversation with Solomon, Nussbaum, and Butler, it becomes evident how intricately Tagore developed this vindication. He turned exploitative media narratives against the colonial state, used Britain’s language and concepts to invite compassion for massacre victims, and formed a powerful, humanizing alliance in the “true space” that lies “between the people” (Arendt qtd. in Butler 2)—between himself, India’s masses, and other elite Indians.
That Tagore could accomplish this much given his own removed-ness from the massacre is immensely compelling. It reminds individuals who are in some way removed from an atrocity that they can reclaim humanity in a language they know, with an audience they can interface with, despite the distances in space and time. It is an idea that resonates with me deeply as I realize, seated in my dormitory in New York, over eleven years after I first read of the Amritsar massacre in New Delhi, that I can shift from experiencing terror to writing in defiance of it.
NOTES
1. I re-encountered the history of this colonial atrocity during my first semester at Columbia, in Professor Susan Pedersen’s fall 2020 lecture course, “History of Twentieth-Century Britain,” where we read Sayer’s article on British media responses to the massacre and Tagore’s letter.2. The Viceroy (at the time, Lord Chelmsford) was the British Crown’s official representative in India and the nominal head of the government of British India. Knighthood is an honor granted by the British sovereign (at the time, King George V) to individuals for their achievements or service in a variety of different fields and disciplines.3. Regarding the question of language and the reach of this letter, it seems clear that Tagore intended for it to reach a far wider audience than solely Chelmsford. Despite the British government’s attempts to censor the letter, its original (English) version was published by the English press, reaching the colonial metropole, and “vernacular” (likely Bengali and Hindi) versions of it was later published by the Indian press. See Associated, Calcutta 2.4. Today, “Anglo-Indian” as an identity usually refers to persons of mixed ancestry. Tagore, however, is referring to an earlier sense of the term—Britons living in India who authored and published their own English newspapers, which were also accessible in the metropole. For more on British media coverage of the Amritsar massacre, see Sayer.5. The broader argument that British colonial rule was degrading to Britons themselves would become central to Indian anti-colonialism, echoed by Tagore’s contemporaries, including M. K. Gandhi. See Nandy on Gandhi’s wish to “liberate the British as much as . . . Indians” (51), and his chapter “The Psychology of Colonialism: Age, Sex, and Ideology in British India” in The Intimate Enemy more generally.6. As an example of the power of such liberal imperialist rhetoric—wielding British "civilization" against "Oriental despotism" to justify colonialism—see Mill 13.
WORKS CITED
Associated, Calcutta. "On the Request of Sir Rabindranath Tagore that he may be relieved of his title of Knighthood." Letter to E. J. Buck, Simla, 2 June 1919. Government of India, Home Department Proceedings, Delhi Records, no. 52, August 1919, https://indianculture.nvli.in/system/files/NAIStoryPDF/13_Tagore%27s_request_to_be_relieved_of_Knighthood.pdf. Accessed 23 Aug. 2022.
Butler, Judith. "Bodies in Alliance and the Politics of the Street." The State of Things, 7 Sept. 2011, Office for Contemporary Art Norway, Venice. Lecture.
Mill, John Stuart. "On Liberty." On Liberty, Utilitarianism, and Other Essays, Oxford UP, 2015, pp. 5-115.
Mukherjee, Sumita. Nationalism, Education, and Migrant Identities: The England-Returned. Routledge, 2010. Routledge Studies in South Asian History.
Nandy, Ashish. "The Psychology of Colonialism: Age, Sex, and Ideology in British India." The Intimate Enemy: Loss and Recovery of Self under Colonialism, E-book ed., Oxford UP, 1983, pp. 1-63.
Nussbaum, Martha C. "Compassion & Terror." Daedalus, vol. 132, no. 1, Winter 2003, pp. 10-26. JSTOR, www.jstor.org/stable/20027819. Accessed 26 Feb. 2021.
Pedersen, Susan. "Aftermath: 'Home,' Ireland, India (1916-22)." History of 20th Century Britain, 24 Sept. 2020, Columbia University, New York City. Lecture.
Sayer, Derek. "British Reaction to the Amritsar Massacre 1919–1920." Past & Present, no. 131, May 1991, pp. 130-64. JSTOR, www.jstor.org/stable/650872. Accessed 26 Feb. 2021.
Solomon, Alisa. "Who Gets to Be Human on the Evening News?" PMLA, vol. 121, no. 5, Oct. 2006, pp. 1585-92. JSTOR, www.jstor.org/stable/25501629. Accessed 26 Feb. 2021.
Tagore, Rabindranath. "Request of Sir Rabindranath Tagore that he may be relieved of his title of Knighthood in view of the policy followed by Government in dealing with the recent troubles in the Panjab." Received by Frederic Thesiger, Viscount Chelmsford, 31 May 1919. Government of India, Home Department Proceedings, Delhi Records, no. 52, August 1919, https://indianculture.nvli.in/system/files/NAIStoryPDF/13_Tagore%27s_request_to_be_relieved_of_Knighthood.pdf. Accessed 23 Aug. 2022. Letter.
Myth, Tradition and Indian Beliefs in Shashi Deshpande\u27s "The Dark Holds No Terrors"
No full textShashi Deshpande is one of India\u27s most well-known novelists today. Women\u27s writing in India has a shorter history than male writing, but we are seeing a rise in the number of women authors whose fiction is being recognized internationally. They have won a slew of national and international awards and grants, and it now appears that women\u27s writing will rise to prominence shortly as they catch up to their male counterparts. While many other women authors, such as Kamla Markandaya, Nayantara Sehgal, Ruth Prawar Jhabvala, Anita Desai, Santha Rama Rao, Attia Hussain, Padmini Sen Gupta, Nargis Dala, Mrinalini Sarabhai, Gita Mehta, Arundhati Roy, Kiran Desai, enrich Indian English Literature, Deshpande occupies a special place She is one of the few authors working today who incorporates literary allusions, myth, and mythology into her work, effortlessly blending it with earlier results.
Deshpande has used Indian myths, legends, and people in many novels as metaphors for events, incidents, happenings, and characters. In many of her books, she incorporates Western folktales. Shashi Deshpande\u27s writings, especially her novel "The Dark Holds No Terrors" (1980), paint a startlingly vivid picture of Indian womanhood\u27s inner world. For too long, it has been made to stay quiet. Deshpande\u27s use of myth and folklore in her novels exemplifies the decolonization of the Indian literary imagination. These devices are handy to the author for illuminating the inner world of women\u27s minds since many of her novels contain female protagonists. 
Pulmonary manifestations in VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome: a systematic review
No full textBackgroundVEXAS (vacuoles, E1 enzyme, X-linked, auto-inflammatory, somatic) syndrome is a newly described auto-inflammatory disease. Many cases feature pulmonary infiltrates or respiratory failure. This systematic review aimed to summarise respiratory manifestations in VEXAS syndrome described to date.MethodsDatabases were searched for articles discussing VEXAS syndrome until May 2022. The research question was: What are the pulmonary manifestations in patients with VEXAS syndrome? The search was restricted to English-language and those discussing clinical presentation of disease. Information on basic demographics, type and prevalence of pulmonary manifestations, co-existing disease associations and author conclusions on pulmonary involvement were extracted. The protocol was registered on the PROSPERO register of systematic reviews.ResultsInitially, 219 articles were retrieved with 36 ultimately included (all case reports or series). A total of 269 patients with VEXAS were included, 98.6% male, mean age 66.8 years at disease onset. The most frequently described pulmonary manifestation was infiltrates (43.1%; n=116), followed by pleural effusion (7.4%; n=20) and idiopathic interstitial pneumonia (3.3%; n=9). Other pulmonary manifestations were: nonspecific interstitial pneumonia (n=1), bronchiolitis obliterans (n=3), pulmonary vasculitis (n=6), bronchiectasis (n=1), alveolar haemorrhage (n=1), pulmonary embolism (n=4), bronchial stenosis (n=1), and alveolitis (n=1). Several patients had one or more co-existing autoimmune/inflammatory condition. It was not reported which patients had particular pulmonary manifestations.ConclusionThis is the first systematic review undertaken in VEXAS patients. Our results demonstrate that pulmonary involvement is common in this patient group. It is unclear if respiratory manifestations are part of the primary disease or a co-existing condition. Larger epidemiological analyses will aid further characterisation of pulmonary involvement and disease management
