1,376 research outputs found

    sj-docx-1-tdo-10.1177_00494755241227466 - Supplemental material for Modified trichrome stain for faster and improved detection of intestinal protozoan parasites

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    Supplemental material, sj-docx-1-tdo-10.1177_00494755241227466 for Modified trichrome stain for faster and improved detection of intestinal protozoan parasites by Priya Datta, Puja Garg, Sadhna Lal Bhasin, Pankaj Malhotra, Surinder Singh Rana and Sumeeta Khurana in Tropical Doctor</p

    Relationship between Crosscutting Concerns and Defects

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    NOTE FROM ACM: It has been determined that this paper plagiarized earlier works. Therefore ACM has shut off access to this paper. The paper by Pankaj Kumar and Kamlesh Dutta plagiarizes the following work: Marc Eaddy, Vibhav Garg, Alfred Aho, Nachiappan Nagappan, Kaitlin Duck Sherwood, "On the Relationship between Crosscutting Concerns and Defects: An Empirical Investigation" found here , as well as the article: Eaddy, M.; Zimmermann, T.; Sherwood, K.D.; Garg, V.; Murphy, G.C.; Nagappan, N.; Aho, A.V.; , "Do Crosscutting Concerns Cause Defects?," Software Engineering, IEEE Transactions on , vol.34, no.4, pp.497-515, July-Aug. 2008 . http://dx.doi.org/10.1109/TSE.2008.36 . For further information, contact the ACM Director of Publications. </jats:p

    An empirical assessment of metrics suite of AOSD in open source projects

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    NOTE FROM ACM: It has been determined that this paper plagiarized earlier works. Therefore ACM has shut off access to this paper. The paper by Pankaj Kumar and Kamlesh Dutta plagiarizes the following work: Marc Eaddy, Vibhav Garg, Alfred Aho, Nachiappan Nagappan, Kaitlin Duck Sherwood, "On the Relationship between Crosscutting Concerns and Defects: An Empirical Investigation" found here . For further information, contact the ACM Director of Publications. </jats:p

    Nontuberculous mycobacteria in fistula-in-ano: A new finding and its implications

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    AbstractObjective/background: Nontuberculous mycobacteria (NTM) are not known to be associated with fistula-in-ano. NTM was detected in three fistula-in-ano patients in our series. In this study, related data was reviewed to find the mycobacterial disease in patients in our database. Methods: In this study, 311 consecutive fistula-in-ano patients operated over 2years were analyzed. The histopathology of anal fistula tract epithelial lining of every operated patient was analyzed and other tests (real-time-polymerase chain reaction [RT-PCR], GeneXpert, and mycobacterial culture) were conducted in patients with high index of suspicion of having mycobacterial disease. Results: Two patients had histopathological features suggestive of mycobacterial disease. Of these, one patient had NTM and the other had Mycobacterium tuberculosis (MTB) on RT-PCR. Four patients had normal histopathology features but tested positive on RT-PCR (2 each for NTM and MTB). Therefore, a total of six patients were tested for mycobacterial disease (3 each for NTM and MTB). Mycobacterium culture was performed in two patients (both NTM) but the result was negative. Five of six patients (NTM=2, MTB=3) presented with delayed recurrences after operation (6–18months after complete healing). Conclusion: NTM can cause fistula-in-ano. It could be an undiagnosed contributory factor in fistula recurrence. Mycobacterial disease (both tuberculous and nontuberculous) may be associated with delayed recurrence of fistula. RT-PCR is highly sensitive and can differentiate between NTM and MTB. It should perhaps be performed in all recurrent and refractory cases

    Sampling hurdles : “Borderline Illegitimate” to legitimate data.

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    In this paper the author discusses how sampling access and recruitment problems encountered in an in-depth interview study heightened her sensitivity to “borderline illegitimate” data. The term illegitimate data usually refers to the data collected during a covert study, whereas “legitimate” data are collected during an overt study. Hence, data collected during any nonconsented period(s) of an overt study lie on the borderline of illegitimacy and legitimacy, and constitute what the author calls borderline illegitimate data. Such data need legitimization before use. The borderline illegitimate data were collected during the pre- and postinterview stages of her study as they explained how medical and ethnic cultures and sensitivity to racism as a topic combined to create sample recruitment difficulties of the study. The author later legitimized them by sharing them with the participants, guaranteeing anonymity, and asking their permission to use them

    Rectovaginal Fistulas Not Involving the Rectovaginal Septum Should Be Treated Like Anal Fistulas: A New Concept and Proposal for a Reclassification of Rectovaginal Fistulas

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    Pankaj Garg,1 Laxmikant Ladukar,2 Vipul D Yagnik,3 Kaushik Bhattacharya,4 Gurleen Kaur5 1Department of Colorectal Surgery, Garg Fistula Research Institute (GFRI), Panchkula, Haryana, India; 2Department of Surgery, Ladukar Surgical Hospital, Bramhapuri, Maharashtra, India; 3Department of Surgery, Banas Medical College and Research Institute, Palanpur, Gujarat, India; 4Department of Surgery, MGM Medical College and LSK Hospital, Kishanganj, Bihar, India; 5Department of Pharmacology, Adesh Medical College and Hospital, Shahbad, Haryana, IndiaCorrespondence: Pankaj Garg, Chief Colorectal Surgeon, Colorectal Surgery, Garg Fistula Research Institute (GFRI), 1042, Sector-15, Panchkula, Haryana, 134113, India, Email [email protected]: Many rectovaginal fistulas(RVF), especially low RVF, do not involve/penetrate the RV-septum, but due to lack of proper nomenclature, such fistulas are also managed like RVF (undertaking repair of RV-septum) and inadvertently lead to the formation of a high RVF (involving RV-septum) in many cases. Therefore, REctovaginal Fistulas, Not Involving the Rectovaginal Septum, should be Treated like Anal fistulas(RENISTA) to prevent any risk of injury to the RV septum. This concept(RENISTA) was tested in this study.Methods: RVFs not involving RV-septum were managed like anal fistulas, and the RV-septum was not cut/incised. MRI, objective incontinence scoring, and anal manometry were done preoperatively and postoperatively. High RVF (involving RV-septum) were excluded.Results: Twenty-seven patients with low RVF (not involving RV-septum) were operated like anal fistula[age:35.2± 9.2 years, median follow-up-15 months (3– 36 months)]. 19/27 were low fistula[ 1/3 EAS involved) and underwent a sphincter-sparing procedure. Three patients were excluded. The fistula healed well in 22/24 (91.7%) patients and did not heal in 2/24 (8.3%). The healing was confirmed on MRI, and there was no significant change in mean incontinence scores and anal pressures on tonometry. RV-septum injury did not occur in any patient.Conclusions: RVF not involving RV-septum were managed like anal fistulas with a high cure rate and no significant change in continence. RV-septum injury or formation of RVF with septum involvement did not occur in any patient. The RENISTA concept was validated in the present study. A new classification was developed to prevent any inadvertent injury to the RV-septum.Keywords: rectovaginal, fistula, anal, incontinence, recurrence, scoring system, fistulotomy, classificatio

    Use of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospital

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    Pankaj Garg, Prashanth Raju, Ewa Sondej, Erwin Rodrigues, Gershan DavisAintree Cardiac Centre, University Hospital Aintree, Liverpool, UKIntroduction: Statin therapy is a well established treatment for hyperlipidemia. However, little is known about prescribing of statins for primary prevention in the real world, and even less about what happens to patients requiring primary prevention who are seen in a secondary care setting. The purpose of this research was to investigate the appropriateness of statin prescriptions by using the Joint British Society cardiovascular disease (JBS CVD) risk score for primary prevention in a large secondary care center.Methods: We retrospectively analyzed 500 consecutive patients in whom a statin prescription was initiated over a four-month period. We excluded patients who met secondary prevention criteria. We used the JBS CVD risk prediction chart to calculate 10-year composite risk. We also studied which statins were prescribed and their starting doses.Results: Of 500 patients consecutively started on statins in secondary care, 51 patients (10.2%) were treated for primary prevention. Of these, seven (14%) patients had a 10-year composite cardiovascular event risk of more than 20% (high-risk category), and were hence receiving appropriate therapy. Three main statins were prescribed for primary prevention, ie, atorvastatin (22 patients, 43%), simvastatin (25 patients, 49%), and pravastatin (four patients, 8%). The statins prescribed were initiated mainly at the 40 mg dose.Conclusions: Statin prescribing in secondary care for primary prevention is limited to about 10% of initiations. There is some overprescribing, because 86% of these patients did not require statins when risk-stratified appropriately. The majority of the prescriptions were for simvastatin 40 mg and atorvastatin 40 mg.Keywords: statins, primary prevention, hypercholesterolemia, cardiovascular disease, retrospectiv

    Cardiovascular magnetic resonance can improve the precision for left ventricular filling pressure assessment

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    This commentary refers to Cardiac magnetic resonance identifies raised left ventricular filling pressure: prognostic implications, by P. Garg et al., https://doi.org/10.1093/eurheartj/ehac207 and the discussion piece Left atrial volume and left ventricular mass for pulmonary capillary wedge pressure assessment with cardiovascular magnetic resonance: accurate enough for clinical use?, by D. Genovese et al., https://doi.org/10.1093/eurheartj/ehac739
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