1,720,982 research outputs found

    Long term follow-up of liver function in Italian haemophilic patients

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    A 14-year follow-up of 153 haemophilic patients treated with clotted factor concentrates was made to assess liver function. Investigations included measurement of alanine amino transferase (ALT), immunoglobulins, HIV antibody, HBsAg, antibody to HBs and HBc antigens, antibodies to HCV (assayed by ELISA-2 and by RIBA-2) and HCV viraemia assessed by PCR. Assessment of liver function also included liver ultrasound scan and oesophageal X-ray. A positive correlation was found between abnormal liver functionand age, HIV infection, HBV infection, HCV infection and hepatomegaly. However, there was no correlation between abnormal liver function and annual clotting factor concentrate use. The increasing incidence of liver insufficiency with increasing age is likely to result in substantial morbidity and mortality amongst haemophilic patients

    Energy Behaviour of NUCA caches in CMPs

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    Abstract—Advances in technology of semiconductor make nowadays possible to design Chip Multiprocessor Systems equipped with huge on-chip Last Level Caches. Due to the wire delay problem, the use of traditional cache memories with a uniform access time would result in unacceptable response latencies. NUCA (Non Uniform Cache Access) architecture has been proposed as a viable solution to hide the adverse impact of wires delay on performance. Many previous studies have focused on the effectiveness of NUCA architectures, but the study of the energy and power aspects of NUCA caches is still limited. In this work, we present an energy model specifically suited for NUCA-based CMP systems, together with a methodology to employ the model to evaluate the NUCA energy consumption. Moreover, we present a performance and energy dissipation analysis for two 8-core CMP systems with an S-NUCA and a D-NUCA, respectively. Experimental results show that, similarly to the monolithic processor, the static power also dominates the total power budget in the CMP system
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