29 research outputs found

    Characterization of spliceosome assembly in cyanidioschyzon merolae.

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    Pre-mRNA splicing is the removal of intervening sequences from pre-messenger RNA in a reaction catalyzed by the spliceosome, which contains five small nuclear RNAs (snRNAs) and more than 100 proteins. Assembly of the spliceosome occurs in a highly ordered manner, making the spliceosome a very complex and dynamic particle. The spliceosome has been studied in yeast and humans but a simpler system would simplify splicing studies. Cyanidioschyzon merolae (Cm) has been shown to have a simpler spliceosome. The goal of this study was to characterize the Cm spliceosome beginning with the question of how large it is. To measure the size of the Cm spliceosome I used glycerol gradient centrifugation and assembly gels to study the assembly pathways. Lastly an attempt was made to study the components of Cm spliceosome by developing an assay in yeast (Saccharomyces cerevisiae) where small molecule inhibitors were used to stall the spliceososme, which could then be purified and its composition studied. --Leaf ii.The original print copy of this thesis may be available here: http://wizard.unbc.ca/record=b197654

    Laughing with an Iranian American Woman: Firoozeh Dumas\u27s Memoirs and the (Cross-) Cultural Work of Humor

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    This essay critically analyzes Firoozeh Dumas\u27s humorous memoirs and situates them in the multiple contexts of post-9/11 Muslim American responses to Islamophobia, women\u27s humor, and Iranian American women\u27s life writing. Drawing on philosophical, feminist, ethnic, and contemporary scientific theories of humor and the methods of literary criticism, the author argues that Dumas employs the beneficial and inclusive (not malign and exclusive) positive mode of humorous personal storytelling to build connection through laughter via the emotional and cognitive shifts structurally central to humor. Dumas addresses multiple audiences and engages in important (cross-) cultural work in a particularly fraught political and cultural climate of anti-Muslim sentiment and tense Iran-U.S. relations

    Colonizing Kashmir: state-building under Indian occupation Colonizing Kashmir: state-building under Indian occupation , by Hafsa Kanjwal, Stanford, Stanford University Press, 2023, xiii + 366 pp., $32, ISBN 978-1-5036-3603-3

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    Kashmiri life is expendable for the Indian state. While the love for the land is close to national imaginaries, the people have been subjected to decades of abuse and violence, and infringement of their basic human rights. In this book, Hafsa Kanjwal delves into the history of Kashmir, tracing the role of two pivotal political figures – Sheikh Abdullah (1947–1953) and Bakshi Ghulam Mohammad (1953–1963) – and their relationship with the Indian project of state-building in Kashmir. The author characterizes this as the ‘politics of life’ (9), where the Indian government and client regimes in Kashmir have normalized occupation with the propagation of ‘development, empowerment and progress’ along with bureaucratic integration and the forging of affective intimate relationships with the people of the state. However, the politics of life and appeals to emotions did not mean that there was an absence of coercive measures used by the Indian state to shape conforming and confronting subjectivities

    Readiness for Hospital Discharge - Adult Patient Form - Urdu Translation

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    The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing. PERMISSION TO USE The Readiness for Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale are available, and permission is granted to use the scales obtained from this website under the following conditions: The scales may not be modified or adapted. The scales may be used for research or for clinical practice. Permission is required from Dr. Weiss to load the scale(s) into the electronic health record and for hospital wide use of the scales. The scales may not be used or incorporated into for-profit/commercial programs. In publications reporting use of the scales, please reference Dr Weiss as the author of the scale and the translator (for non-English Scales) if noted on the scale form. The scales may not be published in manuscripts – only the results of use can be published. You may cite this website as the source of the scales. On publication of results, please send Dr Weiss a copy of the published paper. No further permission is needed if you are using the scales under the above conditions. As a courtesy, please notify the translator listed on the website. You must contact Dr Weiss directly ( [email protected]) for use in electronic health record system, hospital or system-wide use or for other purposes not listed above. To see the scoring rubric, please go to https://www.marquette.edu/nursing/readiness-hospital-discharge-scale.ph

    Adult QDTS, Urdu

    No full text
    The Readiness for Hospital Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale were developed by Dr. Marianne Weiss to measure nurse-sensitive discharge care processes and patient outcomes. Three versions of the scales were developed concurrently for different patient populations – Adult medical-surgical patients, Parents of hospitalized children, and Postpartum Patient mothers (see Weiss & Piacentine, 2006, Weiss et al., 2007, and Bobay et al., 2018 for description of the development and initial testing). Additional scales and information about translation rights are located at Marquette Nursing. PERMISSION TO USE The Readiness for Discharge Scale, Quality of Discharge Teaching Scale, and Post-Discharge Coping Difficulty Scale are available, and permission is granted to use the scales obtained from this website under the following conditions: The scales may not be modified or adapted. The scales may be used for research or for clinical practice. Permission is required from Dr. Weiss to load the scale(s) into the electronic health record and for hospital wide use of the scales. The scales may not be used or incorporated into for-profit/commercial programs. In publications reporting use of the scales, please reference Dr Weiss as the author of the scale and the translator (for non-English Scales) if noted on the scale form. The scales may not be published in manuscripts – only the results of use can be published. You may cite this website as the source of the scales. On publication of results, please send Dr Weiss a copy of the published paper. No further permission is needed if you are using the scales under the above conditions. As a courtesy, please notify the translator listed on the website. You must contact Dr Weiss directly ( [email protected]) for use in electronic health record system, hospital or system-wide use or for other purposes not listed above. To see the scoring rubric, please go to https://www.marquette.edu/nursing/hospital-discharge-scales-quality-of-discharge-teaching-scale.ph
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