25 research outputs found
sj-pdf-1-eso-10.1177_23969873211060819 – Supplemental Material for Micro-embolic signal monitoring in stroke subtypes: A systematic review and meta-analysis of 58 studies
Supplemental Material, sj-pdf-1-eso-10.1177_23969873211060819 for Micro-embolic signal monitoring in stroke subtypes: A systematic review and meta-analysis of 58 studies by Pachipala Sudheer, Shubham Misra, Manabesh Nath, Pradeep Kumar, Deepti Vibha, M.V.Padma Srivatsava, Manjari Tripathia, Rohit Bhatia, Awadh Kishor Pandit and Rajesh K Singh in European Stroke Journal</p
Thermal ecology and activity of the sand fish lizard, scincus mitranus (Scincidae) in Central Arabia
Authors: Al-Johany Awadh M.& Al-Sadoon, Mohamed K. From Department of Zoology,
Author: Al-Farraj Saud A., From Department of Biology
Riyadh, Teachers' College, King Saud University, P.O. Box 4341,
Riyadh 11491. Saudi ArabiaThermal ecology and activity of Scincus mitranus was investigated during winter and summer seasons. Emergence and basking behavior and seasonal activity were studied and analyzed. The lizard was active throughout the year except during cold spells of winter. However, it was found that during winter, daily activity was unimodal, which contrasted with the bimodal pattern during summer. Selected body temperature, critical minimum and maximum were studied and determined in the laboratory
Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention
Original Article
Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention
Sharma, Agrata*; Agarwal, Ayush*; Garg, Ajay1; Vishnu, Venugopalan Y; Nilima, N2; Bhatia, Rohit; Garg, Divyani; Pandit, Awadh K; Joseph, Leve1; Billa, Srujana; Singh, Manmohan3; Suri, Ashish3; Kale, Shashank S3; Gaikwad, Shailesh B1; Srivastava, MV Padma
Author Information
Annals of Indian Academy of Neurology 28(2):p 220-226, Mar–Apr 2025. | DOI: 10.4103/aian.aian_497_24
Open
Abstract
Background and Objectives:
Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Uncertainty still exists regarding the benefit of surgery in the management of supratentorial spontaneous ICH (sICH), especially of the basal ganglia and thalamus. Studies have not shown the clinical benefit of early surgical management compared to best medical management plus delayed surgery, when necessary. Our aim was to compare the efficacy of different neurosurgical interventions with best medical management and best medical management alone.
Methods:
We conducted a single-center, retrospective study at a tertiary care center in India in sICH patients between January 2015 and December 2022. The primary outcome was functional disability evaluated by the modified Rankin Scale (mRS) at 3, 6, and 12 months. Time-to-event outcomes were compared using the Kaplan–Meier curve.
Results:
Among 2600 stroke patients screened, 661 had sICH. Median age was 55 years, and 250 patients (37.8%) underwent neurosurgical intervention. The most common intervention was craniotomy and hematoma evacuation. The median mRS at discharge and follow-up at 3, 6, and 12 months was lower in the conservatively managed group (4, 3, 3, and 3, respectively) compared to the surgical intervention group (5, 5, 5, 4, respectively). However, the ICH score at admission was lower in the conservatively managed group and after adjustment for ICH score, there was no statistically significant difference between the two. Among the interventions, patients undergoing decompression craniectomy had the best functional outcome.
Conclusions:
Neurosurgical intervention was not associated with better functional outcome when compared to conservative management
Competitive strategies and barriers to achieving competitive advantage : a study of two Saudi Arabian industries.
This study focuses on how organisations achieve and sustain competitive
advantage and the possible barriers to this advantage. It first deals with a
theoretical framework by examining related literature on developing a better
understanding of competitive advantage and generic strategies, as well as the
important aspects that may affect a firm's achievement and the sustainability of
its competitive advantage. This study extends the strategic management
literature on competitive advantage and generic strategies mainly based on
Porter's (1980, 1985) work. In particular, instead of the two generic strategies
(differentiation and cost leadership) put forward by Porter, four competitive
strategies are developed. These are (1) price leadership, (2) low cost
differentiation, (3) imitation and (4) differentiation.
Barriers to competitive advantage are conceptionalised in terms of
"strategic coherence" model, which has three aspects. Competitive strategies
require internal consistency referred to as 'competitive coherence'. In addition,
'organisational coherence' needs to be built, involving the structure of internal
and external elements affecting an organisation's ability to achieve its
competitive advantage. The creation of this structure is not automatic. The
difficulties increase with growing dynamism and complexity of the environment
in which an organisation is operating. While competitive and organisational
coherence might exist accidentally, the third aspect developed in this study is
called 'cognitive coherence'. The lack of coherence in one or more of these
aspects is a barrier to a firm achieving and sustaining its competitive advantage.
Secondly, this study reports empirical evidence on the validity of the theoretical
framework. This study takes the case of two different industries (petrochemical
and food) in Saudi Arabia.
Results indicate that all four competitive strategies are possible and
statistically defined. In addition, high-performing firms, in both industries, have
more strategic coherence than lower performing firms. The results suggest that
high-performing firms are able not only to achieve their competitive advantage
but also to sustain it over time. Moreover, in each industry, firms with different
competitive strategies have different barriers to achieving their competitive
advantage. These results are consistent with those found in the existing
literature, lending support to the view that western strategy models seem to be
applicable to developing countries such as Saudi Arabia
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The British administration of Hinduism in North India, 1780-1900.
The thesis is divided into three main sections, each dealing with a different aspect of the religious administration of the British in India. No one section covers the entire period of 1780 to 1900, but they are assembled to give a chronological whole, with some overlapping between them. The first section traces the changes in Hindu traditions of pilgrimage in north India, c. 1780- 1840. Most of the information revolves around three main sites - Aflahabad, Benares and Gaya - partly as a result of source bias: the British had control of these sites from a relatively early date and much eighteenth-century information about the pilgrim industries there has been preserved. This section focuses on the religious behaviour of the Marathas: their patronage of the northern sites and the British interaction with Maratha royals and other elite pilgrims. It looks at the way in which elite pilgrims smoothed the way for non-elite pilgrims to make long and hazardous journeys to the north, setting up traditions of relations with sites and priests that enabled non-elite pilgrimage to continue long after royal patronage declined in the nineteenth century.
This section also considers the changing attitudes of the British to Hindu pilgrimage. Eighteenth-century officers welcomed the advantages inherent in the control of famous pilgrimage sites: the chance to advertise British rule to visitors from non-Company territories, the numerous occasions for pleasing political allies, the receipt of wealth from all over India. Territorial expansion at the turn of the century undid many of these advantages and, with the rise of evangelicalism and the acrimonious debate about the right of a Christian government to profit from idolatry, in the nineteenth century the control of pilgrimage sites began to be seen as a liability.
The second section concentrates on the British regulation of religious disputes. Most of the evidence deals with Hindu-Muslim conflict over religious festivals and cow-slaughter in the cities of the North-Western Provinces. Although most of the incidents examined are from the core of the nineteenth century, c. 1820-1880, earlier incidents are studied in an attempt to understand pre-British practices. Some material from the very end of the century is also examined.
Innovative and influential aspects of British policy are shown to be the judiciary's emphasis on precedent and the consequent creation of intercommunal rights in religious display and of a documented history of local disputes. Pre-British religious disputation is shown to function in an entirely contemporary environment, with communities and individuals' rights of display reflecting only their current position within the locality. An important part of the argument is the extent to which Indians adopted the British methods but, exploiting officers' ignorance of a locality's history, manipulated them to their own ends.
A post-1857 development in British policy, the attempt to build-up "natural leaders" within localities and to get them to control the people's religious behaviour, is important because it highlights the British antipathy to traditional religious leaders. The failure of these "natural leaders" - largely gentlemen of inherited wealth and property and in receipt of British honours and titles - to stop their co-religionists from fighting over the rights of religious display underlines the very big gap between colonial intentions and achievements.
The third section is a discussion of the impact of "objective" scientific and sanitation principles on the celebration of grand Hindu fairs in the last half of the nineteenth century. Particular emphasis is placed on the government's efforts to prevent outbreaks of cholera and plague at the big gatherings. Where once the colonial government had shied away from close relations with Hinduism, warned off by the pious wrath of the evangelicals, now it pursued a radically interventionist course in public Hindu worship, justifying interference with pilgrims and pilgrimage sites in terms of public health. It is clear that this section draws upon the material presented in the first section, but the second is also not without relevance. The British antipathy to religious professionals is shown to be very strong in their late-nineteenth-century administration of pilgrimage sites. These men were consistently alienated from the government and they forfeited few opportunities to declare their hostility to state officials and the Indians who supported them. The fact that priests and pilgrims repeatedly joined forces in opposition to state "improvements" at holy sites, suggested that the independence of activity that was shown in the second section to have characterized religious behaviour in the home locality was strong enough to be transported throughout the Hindi-speaking region.
The conclusion draws together the disparate evidence of the three sections to argue that, over the nineteenth century, the component of religion in community and individual identity was magnified until it became large enough to stand alone as an indicator of identity. It also argues that, particularly for non-elites, participation in religious display and any consequent disputes was an indicator of one's independence, not from members of another religious grouping, but from the economic elite of one's own co-religionists
Information systems project work in a Saudi organisation : an ethnographic study
This study examines IS project trajectories in a Saudi organisation showing how the project is shaped and re-shaped in day-to-day activities. Three project features are adapted to characterise project phenomena: project complexity, embeddedness and project learning.
Accordingly, the first objective is to investigate project complexities showing how they are dynamically changed due re-defining project properties of goals, methods, deadlines and team relations. The second objective is to understand the interactions between project members and external groups and individual from the surrounding context and how those interactions shape and re-shape local project context. The third objective is to analyse the challenges which bound project members’ knowledgeability.
The research methodology incorporates a self-ethnography over twelve months of participation and observation study of three IS projects in a Saudi organisation. Structuration theory is used to guide the research philosophically and to offer an analytical perspective to understand collected data. Structuration theory is implemented to highlight the dynamic nature of project trajectories taking into consideration that project is not a result of an isolated local context or shaped only according to surrounding organisational procedures: rather project trajectories are results of a series of recursive interactions between the project’s local and surrounding contexts, where project member’s knowledgeability plays a role in informing actions.
This research can be considered as a theoretical contribution to IS project management literature. This study is situated in new project management literature as distinct from dominant traditional project management prescriptions. This study suggests a view of the project phenomenon merging the three separate project features: project complexity, embeddedness and learning. On the methodological level, this study introduces the project phenomenon as an ethnographic object stressing its dynamic and social nature embedded in daily activities. Finally, on the context level, this study contributes towards compensating for the paucity of studies about the context of Saudi Arabia in project management and management studies in general
Pramipexole-induced syndrome of inappropriate antidiuretic hormone secretion in a patient with young-onset Parkinson’s disease
Pramipexole, a dopaminergic agonist, has rarely been implicated as a cause of hyponatremia in patients with Parkinson’s disease (PD). Pramipexole-induced stimulation of anti-diuretic hormone results in euvolemic hyponatremia. This is often neglected, and hyponatremia may lead to worsening of the motor symptoms with PD and an unnecessary increase in dopaminergic medications, causing disabling dyskinesias. This case report describes a patient with young-onset PD who developed newonset hyponatremia due to pramipexole-induced syndrome of inappropriate anti-diuretic hormone within 3 months of starting the drug
