25 research outputs found

    sj-pdf-1-eso-10.1177_23969873211060819 – Supplemental Material for Micro-embolic signal monitoring in stroke subtypes: A systematic review and meta-analysis of 58 studies

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    Supplemental Material, sj-pdf-1-eso-10.1177_23969873211060819 for Micro-embolic signal monitoring in stroke subtypes: A systematic review and meta-analysis of 58 studies by Pachipala Sudheer, Shubham Misra, Manabesh Nath, Pradeep Kumar, Deepti Vibha, M.V.Padma Srivatsava, Manjari Tripathia, Rohit Bhatia, Awadh Kishor Pandit and Rajesh K Singh in European Stroke Journal</p

    Thermal ecology and activity of the sand fish lizard, scincus mitranus (Scincidae) in Central Arabia

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    Authors: Al-Johany Awadh M.& Al-Sadoon, Mohamed K. From Department of Zoology, Author: Al-Farraj Saud A., From Department of Biology Riyadh, Teachers' College, King Saud University, P.O. Box 4341, Riyadh 11491. Saudi ArabiaThermal ecology and activity of Scincus mitranus was investigated during winter and summer seasons. Emergence and basking behavior and seasonal activity were studied and analyzed. The lizard was active throughout the year except during cold spells of winter. However, it was found that during winter, daily activity was unimodal, which contrasted with the bimodal pattern during summer. Selected body temperature, critical minimum and maximum were studied and determined in the laboratory

    Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention

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    Original Article Comparison of Long-Term Outcomes in Patients with Supratentorial Spontaneous Intracerebral Hemorrhage Treated with and without Surgical Intervention Sharma, Agrata*; Agarwal, Ayush*; Garg, Ajay1; Vishnu, Venugopalan Y; Nilima, N2; Bhatia, Rohit; Garg, Divyani; Pandit, Awadh K; Joseph, Leve1; Billa, Srujana; Singh, Manmohan3; Suri, Ashish3; Kale, Shashank S3; Gaikwad, Shailesh B1; Srivastava, MV Padma Author Information Annals of Indian Academy of Neurology 28(2):p 220-226, Mar–Apr 2025. | DOI: 10.4103/aian.aian_497_24 Open Abstract Background and Objectives: Intracerebral hemorrhage (ICH) is associated with high mortality and morbidity. Uncertainty still exists regarding the benefit of surgery in the management of supratentorial spontaneous ICH (sICH), especially of the basal ganglia and thalamus. Studies have not shown the clinical benefit of early surgical management compared to best medical management plus delayed surgery, when necessary. Our aim was to compare the efficacy of different neurosurgical interventions with best medical management and best medical management alone. Methods: We conducted a single-center, retrospective study at a tertiary care center in India in sICH patients between January 2015 and December 2022. The primary outcome was functional disability evaluated by the modified Rankin Scale (mRS) at 3, 6, and 12 months. Time-to-event outcomes were compared using the Kaplan–Meier curve. Results: Among 2600 stroke patients screened, 661 had sICH. Median age was 55 years, and 250 patients (37.8%) underwent neurosurgical intervention. The most common intervention was craniotomy and hematoma evacuation. The median mRS at discharge and follow-up at 3, 6, and 12 months was lower in the conservatively managed group (4, 3, 3, and 3, respectively) compared to the surgical intervention group (5, 5, 5, 4, respectively). However, the ICH score at admission was lower in the conservatively managed group and after adjustment for ICH score, there was no statistically significant difference between the two. Among the interventions, patients undergoing decompression craniectomy had the best functional outcome. Conclusions: Neurosurgical intervention was not associated with better functional outcome when compared to conservative management

    Competitive strategies and barriers to achieving competitive advantage : a study of two Saudi Arabian industries.

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    This study focuses on how organisations achieve and sustain competitive advantage and the possible barriers to this advantage. It first deals with a theoretical framework by examining related literature on developing a better understanding of competitive advantage and generic strategies, as well as the important aspects that may affect a firm's achievement and the sustainability of its competitive advantage. This study extends the strategic management literature on competitive advantage and generic strategies mainly based on Porter's (1980, 1985) work. In particular, instead of the two generic strategies (differentiation and cost leadership) put forward by Porter, four competitive strategies are developed. These are (1) price leadership, (2) low cost differentiation, (3) imitation and (4) differentiation. Barriers to competitive advantage are conceptionalised in terms of "strategic coherence" model, which has three aspects. Competitive strategies require internal consistency referred to as 'competitive coherence'. In addition, 'organisational coherence' needs to be built, involving the structure of internal and external elements affecting an organisation's ability to achieve its competitive advantage. The creation of this structure is not automatic. The difficulties increase with growing dynamism and complexity of the environment in which an organisation is operating. While competitive and organisational coherence might exist accidentally, the third aspect developed in this study is called 'cognitive coherence'. The lack of coherence in one or more of these aspects is a barrier to a firm achieving and sustaining its competitive advantage. Secondly, this study reports empirical evidence on the validity of the theoretical framework. This study takes the case of two different industries (petrochemical and food) in Saudi Arabia. Results indicate that all four competitive strategies are possible and statistically defined. In addition, high-performing firms, in both industries, have more strategic coherence than lower performing firms. The results suggest that high-performing firms are able not only to achieve their competitive advantage but also to sustain it over time. Moreover, in each industry, firms with different competitive strategies have different barriers to achieving their competitive advantage. These results are consistent with those found in the existing literature, lending support to the view that western strategy models seem to be applicable to developing countries such as Saudi Arabia

    Information systems project work in a Saudi organisation : an ethnographic study

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    This study examines IS project trajectories in a Saudi organisation showing how the project is shaped and re-shaped in day-to-day activities. Three project features are adapted to characterise project phenomena: project complexity, embeddedness and project learning. Accordingly, the first objective is to investigate project complexities showing how they are dynamically changed due re-defining project properties of goals, methods, deadlines and team relations. The second objective is to understand the interactions between project members and external groups and individual from the surrounding context and how those interactions shape and re-shape local project context. The third objective is to analyse the challenges which bound project members’ knowledgeability. The research methodology incorporates a self-ethnography over twelve months of participation and observation study of three IS projects in a Saudi organisation. Structuration theory is used to guide the research philosophically and to offer an analytical perspective to understand collected data. Structuration theory is implemented to highlight the dynamic nature of project trajectories taking into consideration that project is not a result of an isolated local context or shaped only according to surrounding organisational procedures: rather project trajectories are results of a series of recursive interactions between the project’s local and surrounding contexts, where project member’s knowledgeability plays a role in informing actions. This research can be considered as a theoretical contribution to IS project management literature. This study is situated in new project management literature as distinct from dominant traditional project management prescriptions. This study suggests a view of the project phenomenon merging the three separate project features: project complexity, embeddedness and learning. On the methodological level, this study introduces the project phenomenon as an ethnographic object stressing its dynamic and social nature embedded in daily activities. Finally, on the context level, this study contributes towards compensating for the paucity of studies about the context of Saudi Arabia in project management and management studies in general

    Pramipexole-induced syndrome of inappropriate antidiuretic hormone secretion in a patient with young-onset Parkinson’s disease

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    Pramipexole, a dopaminergic agonist, has rarely been implicated as a cause of hyponatremia in patients with Parkinson’s disease (PD). Pramipexole-induced stimulation of anti-diuretic hormone results in euvolemic hyponatremia. This is often neglected, and hyponatremia may lead to worsening of the motor symptoms with PD and an unnecessary increase in dopaminergic medications, causing disabling dyskinesias. This case report describes a patient with young-onset PD who developed newonset hyponatremia due to pramipexole-induced syndrome of inappropriate anti-diuretic hormone within 3 months of starting the drug
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