2,904 research outputs found

    A novel quantitative technological approach to muscle and exercise dysfunction in the clinical rehabilitation practice of patients with chronic obstructive pulmonary disease

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    La broncopneumopatia cronica ostruttiva (BPCO) è una patologia polmonare eterogenea caratterizzata da tosse produttiva, dispnea e limitazione della tolleranza all'esercizio. Inoltre, la disfunzione dei muscoli scheletrici è una delle conseguenze sistemiche più importanti della BPCO. Infatti, la disfunzione muscolare influisce negativamente sulla capacità di svolgere attività funzionali e aumenta il rischio di mortalità. Tuttavia, tale disfunzione può essere prevenuta e migliorata con l'esercizio fisico nei soggetti affetti da BPCO. In questo contesto, i progressi tecnologici possono ampliare la valutazione della funzione muscolare e consentire di ottenere dati quantitativi nella riabilitazione della BPCO. I tre obiettivi principali di questa tesi erano: (i) Identificare gli attuali metodi di valutazione e trattamento della disfunzione muscolare nella BPCO, concentrandosi sulle tecnologie impiegate e sulla pratica clinica riabilitativa. (ii) Progettare e implementare in ambito clinico riabilitativo un setting tecnologico per valutare quantitativamente la funzione muscolare e la performance funzionale in pazienti con BPCO. (iii) Sviluppare un programma di allenamento per la disfunzione muscolare basata su esercizi eccentrici in pazienti con BPCO. Questa tesi include cinque studi, tra cui tre revisioni sistematiche (RS), uno studio osservazionale prospettico e uno studio randomizzato controllato (RCT). Due RS hanno evidenziato rispettivamente l'eterogeneità dell'approccio nei programmi di allenamento per la disfunzione muscolare e la minore attenzione alle diverse proprietà muscolari nei pazienti con BPCO. Una terza RS ha evidenziato limitazioni nell'implementazione delle tecnologie nel contesto clinico riabilitativo della BPCO. Tuttavia, la valutazione dettagliata della funzione muscolare, supportata da tecnologie portatili, è stata fondamentale per prevedere le prestazioni funzionali nei pazienti con BPCO durante lo studio osservazionale svolto. Inoltre, l'RCT ha mostrato che specifiche modalità di esercizio possono migliorare ulteriormente la funzione muscolare dopo la riabilitazione polmonare nei pazienti con BPCO. In conclusione, l'uso di tecnologie portatili è fondamentale per una valutazione oggettiva, accurata e riproducibile della funzione muscolare e delle prestazioni funzionali nei pazienti con BPCO. Pertanto, è necessario stabilire l’utilizzabilità clinica di tali dispositivi, nonché la loro validità e affidabilità applicata a test specifici e funzionali nella pratica riabilitativa della BPCO.Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by productive cough, dyspnea, and exercise limitation. Moreover, the dysfunction of skeletal muscles is one of the most important systemic consequences of COPD. Muscle dysfunction negatively affects the ability to perform functional activities and increases the mortality risk. However, skeletal muscle dysfunction can be prevented and improved with exercise training in individuals with COPD. In this context, technological advancements can expand the assessment of muscle function and enable obtaining quantitative data in the current COPD practice. The three main objectives of this thesis were: (i) To identify current assessment methods and treatment prescriptions for muscle dysfunction in COPD, focusing on technologies employed and clinical rehabilitation practice. (ii) Design and implementation in the clinical setting of a technological set up to quantitatively evaluate muscle function and functional performance in outpatients with COPD. (iii) To develop a training prescription for muscle dysfunction based on eccentric exercises in inpatients with COPD. This thesis involved five studies, including three systematic reviews (SRs), one prospective observational study, and one randomized controlled trial (RCT). Two SRs respectively showed heterogeneity of approach in training prescriptions for muscle dysfunction and less attention to different muscle properties in patients with COPD. A third SR reported limitations to the implementation of technologies in the clinical setting of COPD. However, the detailed assessment of muscle function, supported by portable technologies, was critical to predict functional performance in patients with COPD during the observational study. Moreover, the RCT showed that specific exercise modalities, may further improve muscle function after pulmonary rehabilitation in patients with COPD. In conclusion, the use of wearable devices is critical for the objective, accurate, and reproducible assessment of muscle function and functional performance in patients with COPD. Therefore, it is necessary to establish the clinical feasibility of such devices, as well as their validity and reliability applied to specific and functional tests in COPD rehabilitation practice

    Rozpor ako východisko, láska ako smer u Simone Weilovej (Contradiction as base, Love as direction in writings of Simone Weil)

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    Article is explaining contradiction and love, Simone Weil‘s essential terms of hermeneutics of human Being. It introduces close relation of these terms with her understanding of God as well as with her overall concept of religion. Author also mentions Simone Weil‘s inspirations with philosophical and spiritual concepts of the East

    “I beg you to tell me what has become of Djamila”: The Political Mobilization of Simone de Beauvoir’s Readers During the Boupacha Affair

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    By Sophia Millman This is a condensed version of a Masters thesis dedicated to the political mobilization of Simone de Beauvoir’s readers. The citations from the letters were translated from French by the author. *** On June 2, 1960, the French government ordered all copies of the daily Algiers edition of Le Monde seized and destroyed to suppress the publication of Simone de Beauvoir’s article “Pour Djamila Boupacha.” Beauvoir, a self-professed “woman of letters”, not “of action[1]”, and one ..

    A comparative study of form and theology in the works of Flannery O'Connor and Simone Weil

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    In this comparative study of the form and theology of Flannery O'Connor and Simone Weil I interrogate how Weil's philosophical writings and her theology illuminate O'Connor's use of both narrative and non-fictional forms, and her Catholicism. The Introduction analyses how Weil's concept of superposed reading provides a new method of approaching both O'Connor, her writings, and O'Connor studies, and focuses on how such apparently different women interconnect. Chapter One explores how both Weil and O'Connor attempt to write their theologies on the souls of their readers yet are each subject to constraints imposed by form. Weil's concept of locating equilibrium between incommensurates is discussed, and her distinctively philosophical approach to fictions and fictionality is used to investigate O'Connor's notion of prophetic fictions and the writer's role. Chapter Two assesses how both writers revivify Christian paradoxes. Weil's monstrous concept of affiiction, and O'Connor's use of the grotesque genre to jolt secular man into an awareness of the sacred are scrutinised. Chapter Three studies how both writers consider an encounter between God and man is possible through the action of grace. My Conclusion interrogates how Weil's work can deepen our understanding of O'Connor's writings, and examines how successful O'Connor is at realising a truly Christian literature. I conclude that despite being a writer of powerful fictions, O'Connor can not be totally successful in her mission as writer-prophet because ultimately fiction escapes orthodoxy

    Microlinices benthovus Simone 2014

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    benthovus, Microlinices Simone, 2014 Microlinices benthovus Simone, 2014: 575–578 (figs 6A–J, 7A–H, 11A–C). Gastropoda, Naticidae Paratypes (22 spc): MZSP 105269. Paratypes 1 (15 spc): MZSP 105270. Paratypes 2 (16 spc): MZSP 105271. Paratypes 3 (7 spc): MZSP 105272. Localities: Brazil, Espírito Santo, off Itaúnas, Abrolhos Slope, 18°59' S, 37°50' W, MD55 sta. DC 73, 637 m depth, 27 May 1987; 1) 19°00' S, 37°48' W, MD55 sta. DC72, 950– 1050 m, 27 May 1987; 2) off Regência, 19°40' S, 37°48' W, MD55 sta. CB77, 790– 940 m depth, 27 May 1987; 3) off Itaúnas, Abrolhos Slope, 19°01' S, 37°47' W, MD55 sta. CB79, 1500–1575 m depth, 28 May 1987. Collectors: P. Bouchet, J.H. Leal and B. Métivier. Preservation: Dry. Remarks: Former MNHN, Paris. The catalogue number MZSP 105250 is mentioned twice in Simone’s (2014) paper, among the paratypes of M. ibitingus Simone, 2014 and M. benthovus. This duplicity was a mistake by the author: the latter is an erroneous designation and should be disregarded. The only valid paratype lots for M. benthovus are the ones shown above.Published as part of Cavallari, Daniel C., Dornellas, Ana Paula S. & Simone, Luiz Ricardo L., 2016, Second annotated list of type specimens of molluscs deposited in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-59 in European Journal of Taxonomy 213 on page 10, DOI: 10.5852/ejt.2016.213, http://zenodo.org/record/384012

    Was bringt die Föderalismusreform? Wahrscheinliche Effekte der geänderten Zustimmungspflicht

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    The recently enacted reform of German federalism is supposed to make legislation faster, more efficient and better. To what extent are these expectations justified? In order to assess the likely effects of the reform, this study uses a research design that was recently applied by the Research and Reference Services of the German Bundestag (parliament): we estimate the future effects of the reform by analyzing the impact it would have had on the legislation in the 14th and 15th term of the Bundestag if it had already been been in force at that time. In particular we ask: To what extent would the number of laws requiring the consent of the states' chamber, the Bundesrat, have been reduced? Which type of laws would have been affected by this reduction - the more controversial ones, or the less controversial ones? Which policy sectors would have seen the greatest reduction? How much would the reduction have increased the government's capacity to act effectively? Would the legislative process have been accelerated? -- Die verabschiedete Föderalismusreform soll die Gesetzgebung in Deutschland schneller, effizienter und besser machen. Inwiefern sind diese Erwartungen berechtigt? Zur Abschätzung der Reformfolgen auf die Bundesgesetzgebung folgen wir in dem vorliegenden Working Paper einer Vorgehensweise, die der Wissenschaftliche Dienst des Bundestages kürzlich in einer Studie angewandt hat: Die Auswirkungen der Föderalismusreform insbesondere auf die Zustimmungspflicht werden anhand der Gesetzgebung der 14. und 15. Legislaturperiode untersucht. Wir fragen insbesondere: Wie stark hätte sich der Anteil der Zustimmungsgesetze verringert, wenn die neuen Zustimmungsregeln schon in diesen beiden Legislaturperioden gegolten hätten? Wären eher zwischen Regierung strittige oder unstrittige Gesetze von der Zustimmungspflicht befreit worden? Welche Politikbereiche wären betroffen? Wie sehr hätte sich die politische Handlungsfreiheit der Bundesregierung erhöht? Wäre die Gesetzgebung durch die veränderten Zustimmungsregeln beschleunigt worden?

    Idea ofiary u Simone Weil

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    Autorka omawia ofiarę, jaką z samej siebie złożyła Simone Weil. Głównym celem autorki artykułu jest wykazanie, iż idea ofiary była najważniejszą myślą w życiu francuskiej filozof. W artykule ukazano myśl o ofierze w życiu i pismach intelektualistki, jak również analogie, które rzucają nowe światło na ofiarę Weil. Jako klucz do interpretacji i zrozumienia ofiary Weil, autorka analizuje myśl Emmanuela Levinasa oraz Józefa Tischnera.The author interprets the sacrifice that Simone Weil filed with itself. The main point of the present article is the assumption that the sacrifice Simone Weil was the most important idea of her life. A thought about the victim is portraying the article in the life and letters of the intellectual, as well as is portraying analogies which are shedding new light on the Weil victim. As the key to interpretation and understanding the her victim, the author is analysing the thought of Emmanuel Levinas and Jozef Tischner.Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego Wiedza Edukacja Rozwój; nr umowy: POWER.03.05.00-00-Z092/17-00

    Effects of Combined Endurance and Resistance Eccentric Training on Muscle Function and Functional Performance in Patients With Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial

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    Objective: To evaluate the adherence to treatment and efficacy of an eccentric-based training (ECC) program on peripheral muscle function and functional exercise capacity in patients with chronic obstructive pulmonary disease (COPD). Design: Prospective, assessor-blinded, randomized controlled trial. Setting: The cardiopulmonary rehabilitation unit of a tertiary subacute referral center. Participants: Thirty (N=30) stable inpatients (mean age 68±8 years; FEV1 44±18% of predicted) with COPD were included in the study. Interventions: Inpatients were randomly assigned to 4 weeks of a combined endurance and resistance ECC (n=15) or conventional training (CON; n=15). Main outcome measures: Quadriceps peak torque (PT) was the primary outcome measure for muscle function. Rate of force development (RFD), muscle activation and quality (quadriceps PT/leg lean mass), 6-min walk distance (6MWD), 4-meter gait speed (4mGS), 10-meter gait speed, 5-repetition sit-to-stand (5STS), dyspnea rate, and mortality risk were the secondary outcomes. Evaluations were performed at baseline and repeated after 4 weeks and 3 months of follow-up. Results: Quadriceps PT, RFD, and muscle quality improved by 17±23% (P<.001), 19±24%, and 16±20% (both P<.05) within the ECC group. Besides, a significant between-group difference for RFD (56±94 Nm/s, P=.038) was found after training. Both groups showed clinically relevant improvements in 6MWD, 4mGS, dyspnea rate, and mortality risk, with no significant differences between groups. Conclusion: Combined endurance and resistance ECC improved lower limbs muscle function compared with CON in inpatients with COPD. In contrast, ECC did not further improve functional performance, dyspnea, and mortality risk. ECC may be of particular benefit to effect on skeletal muscle function in patients with COPD

    My life on the road: the exhilarating experience of travel

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    VERSION FRANÇAISE ICI By Tiphaine Martin Researcher at Babel, University of Toulon, Member of the editorial board of Simone de Beauvoir Studies and author of a doctoral dissertation about Simone de Beauvoir's travels Translated from French by Marine Rouch (under the kind supervision of her dear friend Daniel Sawyer) I will begin with a brief criticism of the French edition. While the translation is very pleasant and captures Gloria Steinem's fluidity, humor and appetite for life, there is no..

    Problematiche dell’indotto Fiat di Cassino: proposte per la valorizzazione delle PMI e il rilancio del territorio. Un modello di intervento per rilanciare il sistema

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    GATTI M., GATTI C., PROIETTI L., SIMONE C., Problematiche dell’indotto Fiat di Cassino: proposte per la valorizzazione delle PMI e il rilancio del territorio. Un modello di intervento per rilanciare il sistema produttivo di Cassino, Bic Notes – Quaderni di Bic Lazio, Numero Speciale, 2006, 9-152 Volume senza attribuzioni ai singoli AutoriM. CATS, CATS C., L. Proietti, SIMONE C. Issues industries Fiat Cassino: proposals for the development of SMEs and the revitalization of the area. A model of intervention to revive the productive system of Cassino, Bic Notes - Papers Bic Lazio, Special Issue, 2006 9-152 Volume without attribution to individual author
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