1,721,220 research outputs found
Is fertility reduced in ovulatory women with polycystic ovary syndrome? An opinion paper
No full textPolycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility; however, whether women with PCOS and spontaneous or drug-induced ovulatory cycles have the same reproductive potential as non-PCOS controls is a matter of debate. In the present opinion paper, the author takes the opportunity to summarize the collective evidence supporting the hypothesis of reduced fertility potential in women with PCOS, regardless of ovulatory status, and speculate that reduced reproductive potential may be caused by altered oocytes, embryo and endometrial competence, and infertility-related co-morbidities as well as an increased risk of pregnancy complications
Large randomized controlled trials in reproductive medicine. another battle won by biases and confounders?
No full textNo abstract availabl
Harbin consensus conference and quality of infertility trials: reflections of a scientist on the Italian experience
Full text linkDuring the days August 22-24, 2013 has been held in Harbin (China) an International Consensus Conference aimed to improve the quality and the reporting of the randomized controlled trials (RCTs) in infertility and subfertility field. I, as Italian scientist with experience in clinical infertility trials, was invited to have a speech on the Italian experience in RCTs, with particular regard for the surgical trials. Considerations on this subject were particularly interesting to highlight pitfalls and triumphs of research in Italy
Aromatase Inhibitors for Ovulation Induction
No full textNormogonadotropic anovulation, including polycystic ovary syndrome (PCOS), is one of the main causes of infertility. Recent meta-analysis and randomized controlled trial suggest the use of aromatase inhibitors (ie, letrozole) as effective drug and first-line treatment to restore fertility in these patients. The current manuscript will give a critical, provocative, and personal point of view on the topic
Safety of laparoscopy vs laparotomy in the surgical staging of endometrial cancer: A systematic review and metaanalysis of randomized controlled trials
No full textLaparoscopy or minilaparotomy as minimally invasive surgical approach for uterine leiomyomas? An unsolved question
No full text
Menstrual preconditioning for the prevention of pregnancy complications in women with polycystic ovary syndrome (PCOS): Clinical opinion or viewpoint - This is the question
No full textWe have read with great interest the Clinical Opinion recently published on menstrual preconditioning for the prevention of pregnancy complications in women with polycystic ovary syndrome (PCOS).1 This paper provides a very interesting and provocative view on the potential role of menstrual shedding on the genesis of the increased incidence of the obstetric and/or neonatal complications observed in women with PCOS.2 Moreover, it seems to be more of a personal viewpoint than a clinical opinion because many statements/topics are not adequately balanced, especially for a reader without sufficient experience in the field
Pregnancy complications in women with polycystic ovary syndrome: Importance of diagnostic criteria or of phenotypic features?
No full textSir,
We read with great interest the retrospective matched cohort study
recently published in Human Reproduction by Kollmann et al. (2015)
aimed to evaluate the prevalence of adverse maternal and neonatal
outcomes in different populations of women with polycystic ovary syndrome
(PCOS) diagnosed according to the three main recommendations
of the National Institute of Health (NIH), of the European
Society of Human Reproduction and Embryology (ESHRE)/American
Society of Reproductive Medicine (ASRM) and of the Androgen Excess
and PCOS Society (AE-PCOS). A high prevalence of pregnancy complications
was observed in all PCOS populations, irrespectively from
the criteria adopted to diagnose the PCOS
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