599 research outputs found
Elements of Okinawan Trauma in the Literature of Medoruma Shun
No full textThis thesis surveys a selection of fiction and non-fiction by Okinawan author and activist, Medoruma Shun. The attempt is to explore Medoruma's unique depiction of the continuous effects of the Battle of Okinawa on Okinawa and Okinawan people up to the present
KNPR Interview
No full textSarah Shun-lien Bynum writes stories that border on the supernatural. Her novel, Madeline is Sleeping, focused on a little girl shifting between the dream world and reality. But her latest book deals very much with the real world: Ms. Hempel Chronicles is seen through the eyes of a teacher who is hopeful for her students, but disillusioned with her own life. Author Sarah Shun-lien Bynum talks to us about the joy of childhood, and what we lose in the shift to adulthood
Mu qin dui hai zi xiu que biao xian de fu mian kan fa yi yu ce mu qin guo du bao hu huo yan ge kong zhi hai zi de xing wei, ji Zhong xi wen hua zai dang zhong de jiao se zhi yan jiu diao cha
No full textChan, Shun Lai Carol.Thesis M.Phil. Chinese University of Hong Kong 2014.Includes bibliographical references (leaves 111-126).Abstracts and appendix also in Chinese.Title from PDF title page (viewed on 15, November, 2016).Chan, Shun Lai Carol
Recommended from our members
Biological and Synthetic Locomotion in Newtonian and Complex Fluids at Low Reynolds Number
No full textLife under the microscope is significantly different from our experiences in the macroscopic world. Inertial effects, which govern motion at the macroscopic world, become subdominant to viscous forces at small length scales. The Reynolds number (Re) quantifies the relative importance of inertial to viscous forces. Microorganisms, such as bacteria and spermatozoa, inhabit environments with typical Re between 10̄̄⁻⁵ and 10⁻². The absence of inertia imposes stringent constraints on the types of effective locomotion strategies. This also poses a fundamental challenge in designing synthetic swimmers and fluid transport systems at microscopic scales. Interestingly, microorganisms have evolved diverse strategies to achieve locomotion. This thesis is devoted to studying the fluid mechanics of biological and synthetic locomotion at low Reynolds number under three themes: swimming microorganisms, synthetic locomotion, and locomotion in complex fluids. The first theme focuses on using different idealized hydrodynamic models to study the swimming of microorganisms. Under this theme, we extend the classical Taylor's swimming sheet model to analyze the unsteady inertial effects in flagellar swimming. We also present a hydrodynamic investigation of an interesting double-wave structure observed in insect sperm flagella. We turn our attention to synthetic locomotion in the second theme. Different physical mechanisms are explored to design synthetic micro-swimmers, which have many potential biomedical applications, such as microsurgery and targeted drug delivery systems. Specifically, we exploit elasticity and extensibility of a body to design locomotion strategies. Finally, the third theme concerns locomotion in complex fluids. Most biological fluids are indeed polymeric and hence display non-Newtonian rheological properties. We investigate the idea of taking advantage of the nonlinear rheological properties of a complex fluid to enable locomotion otherwise impossible in a Newtonian fluid. Simple mechanisms are designed to exploit the non- Newtonian stresses for micropropulsion and micropumping. The results are also applied to developing a microrheological technique based on information from locomotio
SYZ Mirror Symmetry for Dirichlet Branes
No full textChung, Shun Wai.Thesis M.Phil. Chinese University of Hong Kong 2016.Includes bibliographical references (leaves ).Abstracts also in Chinese.Title from PDF title page (viewed on …)
[[alternative]]The Study of Improving Chinese Input Methods and The Implementation of NTNU-Master Input Method
No full text[[abstract]]Chinese Character Input on computers is the basic ability in the east, especially in Taiwan, Hong Kong and China. If someone can input Chinese characters quickly, then he can improve his ability in using computers to do many things.
In this study, we stand on some famous input methods, like ChangJie, and other input methods based on ChangJie’s method. We try to develop some techniques, such as rearranging the ChangJie alphabets, encoding the characters with 3 codes, reducing the numbers of strokes using space bar, etc. We compare our results with ChangJie and Dy-Sin-Cang-Jie by statistical techniques in typing lots of articles. We named this method as NTNU-Master input method. The basic concept was originally designed by Dr. Shun-Shii Lin. This study is the first one to implement the system and analyze it.
After some experiments, we get some encouraging results. Successfully, we are able to reduce the average number of strokes for typing Chinese characters.
Recommended from our members
A note on the breathing mode of an elastic sphere in Newtonian and complex fluids
No full textExperiments on the acoustic vibrations of elastic nanostructures in fluid media have been used to study the mechanical properties of materials, as well as for mechanical and biological sensing. The medium surrounding the nanostructure is typically modeled as a Newtonian fluid. A recent experiment however suggested that high-frequency longitudinal vibration of bipyramidal nanoparticles could trigger a viscoelastic response in water-glycerol mixtures [Pelton et al., "Viscoelastic flows in simple liquids generated by vibrating nanostructures," Phys. Rev. Lett. 111, 244502 (2013)]. Motivated by these experimental studies, we first revisit a classical continuum mechanics problem of the purely radial vibration of an elastic sphere, also called the breathing mode, in a compressible viscous fluid and then extend our analysis to a viscoelastic medium using the Maxwell fluid model. The effects of fluid compressibility and viscoelasticity are discussed. Although in the case of longitudinal vibration of bipyramidal nanoparticles, the effects of fluid compressibility were shown to be negligible, we demonstrate that it plays a significant role in the breathing mode of an elastic sphere. On the other hand, despite the different vibration modes, the breathing mode of a sphere triggers a viscoelastic response in water-glycerol mixtures similar to that triggered by the longitudinal vibration of bipyramidal nanoparticles. We also comment on the effect of fluid viscoelasticity on the idea of destroying virus particles by acoustic resonance
Molecular mechanisms of cytotoxicity induced by ribosome-inactivating proteins in mammalian cells
No full textRibosome-inactivating proteins (RIP) represent a family of plant and bacterial toxins that inhibit protein synthesis and are cytotoxic to mammalian cells. Ricin is isolated from seeds of the castor bean plant and has potential as a weapon of bioterrorism. Shiga-like toxins (stx) are produced from enterohemorrahagic Escherichia coli strains, and contamination of food by stx represents a substantial public health threat. Both ricin and stx consist of A and B chains. The A-chain of each protein inactivates the ribosome by cleaving an adenine from the ribosomal RNA. The B-chain of ricin (RTB) binds to galactose binding sites on the cell surface while the pentameric B subunit of stx binds to the cell surface receptor, globotriaosylceramide to facilitate cell entry. While both ricin and stx inhibit protein synthesis and induce cell death, the molecular mechanisms that underlie these effects are relatively unexplored. An ultimate goal of this research is to produce recombinant mutant ricin A-chain (RTA) proteins to study the role of protein synthesis inhibition in ricin-induced cytotoxicity. Therefore, we were interested in establishing a mammalian cell culture model that was sensitive to RTA alone. The cell line MAC-T, an immortalized, nontransformed epithelial cell line, was more sensitive than Vero cells and HeLa cells in terms of the time it took to induce caspase-3/7 activation. While ricin induced higher caspase-3/7 activity than RTA at lower concentrations (0.1 to 10 ng/ml), similar caspase activation was observed at concentrations of 0.1 µg/ml with either protein. Ribosome depurination, protein synthesis inhibition, and apoptosis were observed in MAC-T cells treated with RTA alone. RTA alone also induced JNK and p38 MAP kinase activation in a time- and concentration-dependent manner that preceded apoptosis. Inhibition of the JNK pathway by chemical inhibitors or small interfering RNA reduced RTA-induced apoptosis. In contrast, inhibition of the p38 MAP kinase pathway had little effect on RTA-induced apoptosis. In summary, the major findings of this research are the establishment of the MAC-T cell line as a sensitive cell culture model for future study of ricin and the finding that the JNK pathway plays a major role in RTA-induced cytotoxicity.M.S.Includes bibliographical referencesby Ju-Shun Chen
, 062007 (2021)]
No full textThis article was originally published online on 17 June 2021 with an error in the author list. Alan Chen Hou Tsang should have appeared as Alan Cheng Hou Tsang. The author list is correct as it appears above. All online versions of the article were corrected on 18 June 2012; the article is correct as it appears in the printed version of the journal
- …
