1,721,126 research outputs found
Medical therapy for heart failure with preserved ejection fraction: Still a minefield, but with new hope
No full textTowards a phenotype profiling of the patients with heart failure and preserved ejection fraction
No full textThe prevalence of heart failure with preserved ejection fraction (HFpEF) is increasing and prognosis remains poor, with a high risk of mortality or hospitalizations for worsening heart failure events. Apart from sodium-glucose cotransporter-2 inhibitors and diuretics, the management of HFpEF is nowadays based on the different aetiologies and cardiovascular or non-cardiovascular comorbidities. A great heterogeneity of clinical profiles has been described in HFpEF, with several recent studies focused on the identification of different HFpEF phenotypes. In this review, we summarize available evidence on phenotype profiling in HFpEF, describing the different phenotypes with the relative therapeutic implications, and reporting other specific clinical conditions relevant for HFpEF differential diagnosis
Ejection fraction in heart failure: just become Emperor's new clothes?
No full textThis article refers to 'A comprehensive characterization of acute heart failure with preserved versus mildly reduced versus reduced ejection fraction - insights from the ESC-HFA EORP Heart Failure Long-Term Registry' by A. Kaplon-Cieslicka et al., published in this issue on pages 335-350
April 2021 at a glance: focus on systolic function, quality of life and treatment in heart failure
No full textAssessing aortic flow with doppler echocardiography in cardiogenic shock: A crucial diagnostic tool
No full textPurposeCardiogenic shock still has a high mortality. In order to correctly manage these patients, it is useful to have available haemodynamic parameters, invasive and non-invasive. The aim of this review is to show the current evidence on the use of echocardiographic aortic flow assessment by left ventricular outflow tract - velocity time integral.MethodsPublications relevant to the discussion of echocardiographic aortic flow assessment by left ventricular outflow tract - velocity time integral and cardiogenic shock, were retrieved from PubMed (R).ResultsLeft ventricular outflow tract - velocity time integral is an easily sampled and reproducible parameter that has already been shown to have prognostic value in various cardiovascular pathologies, including myocardial infarction and heart failure. Although there are still few data available in the literature, the LVOT-VTI also seems to have an important role in CS from prognosis to guidance in the escalation/de-escalation of vasoactive therapy and to support devices by allowing an estimate of patient's probability of response to fluid administration.ConclusionAortic flow assessment can become a very useful invasive parameter in the management of cardiogenic shock.LVOT-VTI and its role in cardiogenic shock. LVOT-VTI, left ventricular outflow tract-velocity time integral. imag
Diuretic De-Escalation in Response to HF Therapy: Are We Closer to Reduced Reliance on Diuretics?
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