1,721,240 research outputs found

    Reversal of ticagrelor-induced arrhythmias and cheyne-stokes respiration with aminophylline infusion

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    Dyspnea and bradyarrhythmias are frequent adverse effects (AEs) of ticagrelor. AEs commonly occur within the first week of therapy, are dose related and usually mild, but sometimes they may cause drug discontinuation. Currently, the exact mechanisms of ticagrelor-related AEs have not been definitively explained. In addition to the prevalent theory of adenosine overload, other reasonable mechanism like a direct central stimulation hypothesis was suggested. We present a case of incessant Cheyne-Stokes respiration associated with heart rate instability in patient with congestive heart failure and non-ST-segment elevation myocardial infarction, supporting the use of aminophylline as a potential reversal agent of ticagrelor-related AEs

    Advances in ostracodological research - Selected papers from the 17th International Symposium on Ostracoda

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    The nine papers collected in this special issue of Micropaleontology are a selection of contributions on presented at the 17th International Symposium on Ostracoda (ISO), which was held in Rome, Italy, on 23rd-26th July 2013, and attended by 141 scientists from 29 countries (see text-figure 1)
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