1,720,987 research outputs found
Nuclear Medicine Imaging of Joint Prosthesis Infection
No full textThis comprehensive pictorial case-based atlas of radionuclide imaging in infection and inflammation comprises a diverse group of excellent cases, many using hybrid SPECT/CT and PET/CT imaging. The cases cover a wide spectrum of infection and inflammation in multiple organ systems from brain to feet, including bone, soft tissues, lung, liver, spleen, heart and major vessels, fever of unknown origin, prosthetic joint and implanted devices, vascular grafts, catheter infections, and infections related to hardware in bone. Infections and inflammation associated with chronic inflammation in diseases such as rheumatoid arthritis, sarcoidosis, Sjögren’s disease, vasculitis, and atherosclerosis are also included. The imaging is with commercially and routinely available radiopharmaceuticals such as 67Ga-citrate or the newer 18F-FDG in PET imaging, and 111In-oxine or 99mTc-hexamethylpropyleneamine oxime (Ceretec; GE Healthcare)–labeled white blood cells, 3-phase bone and sulfur colloid bone marrow scanning, and monoclonal antibodies.
The book is divided into 13 chapters covering a wide spectrum of infection and inflammation imaging in the entire body. It is the end result of collaborative hard work by many medical professionals from medical centers throughout Italy, through their involvement in the study group on inflammation and infection of the Italian Association of Nuclear Medicine. Some cases in this atlas are not routinely or frequently seen in a general nuclear medicine practice and thus can serve as a good go-to reference
The role of conventional radiography and scintigraphy in the third millennium
No full textImaging represents a cornerstone for diagnosing and monitoring rhaumatic diseases. In the last years with the availability of highly effective therapies, demand for the technical performance of imaging has increased exponentially, leading to a rapid development of new technologies. Despite these advances conventional radiography and bone scintigraphy continues to provide enormous diagnostic and prognostic help. This chapiter focuses on the roles of CR and BS in rheumatological clinical practice, taking into account their performance in comparison with newer imaging techniques
Transient regional osteoporosis
No full textTransient osteoporosis of the hip and regional migratory osteoporosis are uncommon and probably underdiagnosed bone diseases characterized by pain and functional limitation mainly affecting weight-bearing joints of the lower limbs. These conditions are usually self-limiting and symptoms tend to abate within a few months without sequelae. Routine laboratory investigations are unremarkable. Middle aged men and women during the last months of pregnancy or in the immediate post-partum period are principally affected. Osteopenia with preservation of articular space and transitory edema of the bone marrow provided by magnetic resonance imaging are common to these two conditions, so they are also known by the term regional transitory osteoporosis. The appearance of bone marrow edema is not specific to regional transitory osteoporosis but can be observed in several diseases, i.e. trauma, reflex sympathetic dystrophy, avascular osteonecrosis, infections, tumors from which it must be differentiated. The etiology of this condition is unknown. Pathogenesis is still debated in particular the relationship with reflex sympathetic dystrophy, with which regional transitory osteoporosis is often identified. The purpose of the present review is to remark on the relationship between transient osteoporosis of the hip and regional migratory osteoporosis with particular attention to the bone marrow edema pattern and relative differential diagnosi
Autosplenectomy and antiphospholipid antibodies in systemic lupus erythematosus: a pathogenetic relationship?
No full textTo describe a systemic lupus erythematosus (SLE) patient with functional asplenia and antiphospholipid syndrome (APS) and to review the literature to better define its pathogenesis and diagnosis, emphasizing a possible relationship with antiphospholipid antibodies (aPL). METHODS: Descriptive report of 1 case and review of the literature by means of a MEDLINE search from 1966 to 2002. RESULTS: A SLE patient presented with cutaneous vasculitis and an unexpected thrombocytosis which resulted from autosplenectomy. Subsequently, she developed full-blown APS. In the literature, autosplenectomy has been described only in 1 other case of APS secondary to SLE. However, clinical or laboratory features linked to aPL occurred in several other cases among the 17 cases reported with functional asplenia. CONCLUSIONS: Autosplenectomy in SLE may be pathogenetically related to aPL. Thrombocytosis, unusual in SLE, may be a diagnostic clue of this condition. Pneumococcal vaccination is warranted to prevent life-threatening infections that frequently complicate this asplenia
Medicina nucleare e reumatologia. Integrazioni diagnostico-terapeutiche [The role of nuclear medicine in rheumatology. Diagnostic-therapeutic integration]
No full textRassegna sulle applicazioni della medicina nucleare in reumatologi
Immunoscintigraphy in malignant melanoma: A five-year clinical experience
No full textImmunoscintigraphy (IS) with 99Tcm-labelled anti-melanoma monoclonal antibody F(ab')2 fragments was performed in 135 melanoma patients, 64 males and 71 females, aged 19-82 years (mean 52.3 years) between December 1987 and December 1991. The first group of IS was performed in 50 patients before surgery to assess optimal management: seven true positive and one true negative were obtained in ocular and visceral melanomas, while in cutaneous MM sensitivity, specificity and accuracy in assessing lymph node involvement were, respectively, 61.5, 93.3 and 83.7%. The second group of 128 IS is relative to 85 patients in follow-up: excluding 13 cases with known metastatic disease and 12 inconclusive tests, sensitivity, specificity and accuracy were, respectively, 83.3, 98.8 and 96.1%. Immunoscintigraphy is free of side effects even after repeated administrations and is a useful adjunct to standard diagnostic techniques as a basis for treatment decisions
Infezioni dell’osso e dei tessuti molli nelle fratture esposte. Approcci diagnostici e terapeutici.
No full textImmunoscintigraphic localization in a benign thyroid neoplasm of a monoclonal antibody directed against melanoma
No full textn a prospective study for evaluation of the use of a monoclonal antibody directed against melanoma in the staging of patients affected by malignant melanoma, we report monoclonal antibody uptake in a follicular thyroid adenoma. Computed tomography, ultrasonography, and pertechnetate scintigraphy did not provide a certain diagnosis. Only pathologic examination of the surgical specimen was conclusive
La medicina nucleare in reumatologia: un valido strumento diagnostico e terapeutico
No full textIl lavoro è una revisione narrativa che analizza le possibili applicazioni delle tecniche di imaging nucleare in reumatologi
Predictive value of gated-SPECT myocardial perfusion imaging in type II diabetic patient with and without coronary artery disease
No full text- …
