1,721,087 research outputs found

    Local recurrence of colo-rectal cancer: Risk factors and preventive measures

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    Abstract The local recurrence of colo-rectal cancer, still represents the major reason for the failure of surgical treatment. Several risk-factors of recurrence can be identified and grouped in categories according to different criteria (anatomo-clinical histopathological, biological, technical). Some of them represent undoubtedly proved risk factors of local recurrence, such as advanced stage, distal location, DNA abnormalities, lymphovascular invasion, whereas others are still under investigations (immunology of the tumor, oncogenes, antigens, role of mesorectal excision, pelvic-lymphoadenectomy etc). The identification of risk factors of local recurrence in colo-rectal cancer is of utmost importance since relevant technological innovations in the field of surgical treatment (TEM, laparoscopy) and adjuvant treatment (intra-cavitary radiotherapy, chemotherapy, immunotherapy etc) need a precise evaluation of the patients to be applied successfully

    Diagnosis and Treatment of Primary Tumors of the Appendix: a Critical Review

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    Introduction: The aim of the current paper was to critically collect, select and summarize the evidence regarding diagnosis, treatment and follow up of primary tumors of the appendix. Methods: A literature review was performed by search and review of the scientific studies pertaining to the subject of our inquiry. Results: Recommendations regarding pimary tumors of the appendix were formulated on the basis of the collected evidence. Conclusion : Primary tumors of the appendix are rare and a high index of suspicion is required not to miss a potentially life threatening medical condition
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