130,756 research outputs found

    A generalised program for fuel cell systems simulation

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    A computer program simulating the performance of a fuel cell system has been developed for the analysis of small-scale power plants and uotomotive technologies. FC2000 (Fuel Cells 2000) is based on a Sequential Modular Approach, is coded in Fortran and is user-interfaced by a preprocessor written in Visual Basic. All the system is compatible with a Window environment. Models describing fuel cell equipments were either home developed or acquired from already existing codes desdcribed in literature (Pierucci et alt., 1985), while the preprocessor was specifically created for this application. FC2000 has been succesfully applied to the study and design of transportation technologies and power-plant stationary systems. The paper will describe FC2000 structure, will provide the content of specific fuel cell models and finally will discuss the results of a typical design where an innovative solution is proposed to increase process efficiencies. © 2002 Elsevier B.V. All rights reserved

    Heat and mass transfer in roast beef cooking. Temperature and weight loss prediction

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    The development of food processes, ingredients and formulations is a daily topic for the food industries. Model-based product, process and equipment design are getting increasing industrial attention, due to the high potential in matter of time and money saving. Bringing these advantages to the consumers’ table by the application of this approach is one of the ultimate challenges of food and bioprocess engineering. This work aims to consider roast beef cooking as a practical, widespread, case study. A computational model, which correlates temperature, time and weight loss for a standard piece of meat cooked in oven, is developed and validated with experiments. The thermal properties are derived with a general approach, applicable to other food. The heat and mass transport equations are based both on conservation laws and on the cooking conditions

    Vitamin D and Sphingolipids: Role in Bone and Neural System

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    1-Alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) is known to play an important physiological role on growth and differentiation in a variety of nonmalignant and malignant cell types through classical actions, mediated by its specific receptor (VDR), and nongenomic actions resulting in the activation of specific signalling pathways. Due to the broad distribution of Vitamin D Receptor (VDR) in many tissues and the ability of 1,25(OH)2D3 to regulate fundamental processes, such as cell proliferation and differentiation, this steroid hormone has been suggested in the treatment of different diseases, from cancer to neurodegenerative diseases. In fact, structural 1,25(OH)2D3 analogues, with weaker collateral effects, have recently entered in clinical trials. Other interesting molecules due to their pleiotropic actions are the bioactive sphingolipids (SLs), in particular ceramide (Cer) and sphingosine 1-phosphate (S1P). Cells maintain a dynamic balance of these metabolites since Cer and sphingoid bases mediate cell death, while S1P exerts mitogenic effects and promotes differentiation of several cell types including osteogenic and neural cells. The biological actions of 1,25(OH)2D3 and SLs, in particular S1P, share many common effectors, including calcium regulation, growth factor expression, inflammatory cytokines, etc., but whether they could act synergistically is still unknown and deserves further investigation
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