1,721,087 research outputs found
Antiviral treatment of HCV-related cirrhosis
progression of fibrosis, liver decompensation and the onset of hepatocellular carcinoma. However, the results of therapy are different
according to the different clinical stages of cirrhosis. In patients with bridging fibrosis or histological cirrhosis international trials have
demonstrated that the sustained virological response to the highly active combination ofpegylated interferon plus ribavirin was substantially
similar to that observed in subjects with chronic hepatitis C without cirrhosis. Few data are available as to the efficacy and tolerability of
antiviral treatment in patients with fully developed clinical cirrhosis, with or without decompensation, and all studies to date underscore
the difficulties in the management of the more frequent and severe side effects in these patients.
In patients with a more severe disease who do not achieve a sustained virological response, an alternative option is to reduce or suppress
inflammation and fibrosis progression with long-term suppressive therapy in the hope to prevent clinical deterioration and the onset of
hepatocellular carcinoma. Three international trials are currently evaluating the use of antiviral treatment as a maintenance antiviral
therapy
Complications following percutaneous liver biopsy. A multicentre retrospective study on 68,276 biopsies
Differential diagnosis between benign and malignant biliary tract obstruction: discriminative usefulness of some clinical and laboratory data
[Virological and clinical aspects of multiple hepatitis virus infections: preliminary data of an italian multicentre study]
Aspetti virologici e clinici delle infezioni multiple da virus epatitici: dati preliminari di uno studio multicentrico nazionale.
Azathioprine treatment in a patient with HBsAg-positive acute viral hepatitis complicated by bridging necrosis
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