1,720,976 research outputs found
MODERATE-DOSE INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF JOB'S SYNDROME
Full text linkJob's syndrome (or hyperimmunoglobulinemia E syndrome) is a rare genetic disease characterized by skin eczema, pyogenic 'cold' abscesses, sinopulmonary recidivous infections and high IgE plasma concentrations. Job's syndrome treatment is not satisfactory and cases studied are still limited. To describe the effects of IVIG therapy in a 37-year-old woman with hyper IgE syndrome and pneumonia. We measured IgE serum by immuno-fluorometric test and neutrophil chemotaxis by migration in a Boyden chamber before and after MG therapy. A moderate dose of IVIG resolved the clinical-radiological signs of the S. aureus bronchopneumonia and improved cytologic and biohumoral parameters. Intravenous immunoglobulins represent a useful treatment for acute pneumonia in Job's syndrome
TREATMENT OF HEART FAILURE AND ASCITES WITH ULTRAFILTRATION IN PATIENTS WITH INTRACTABLE ALCOHOLIC CARDIOMYOPATHY.
No full textBackground. In Western countries the excess of alcohol intake causes, secondary, non ischaemic cardiomyopathy and cirrhosis. Frequently, therapy is not effective so ultrafiltration was tried on patients affected, with positive effects on life quality. We tried to verify utility and tolerance to peritoneal ultrafiltration in a group of subjects affected by heart failure secondary to alcoholic cardiomyopathy, refractary to conventional therapy.
Methods. Sixteen patients (14 males, 2 females) with heart failure and ascites affected by alcoholic cardiomyopathy were studied. All subjects were in IV class NYHA (New York Heart Association); ejection fraction (EF) was evaluated by echocardiogram and ascites by abdominal ultrasound. Patients were submitted to clinical exam, body weight, abdominal circumference, diuresis and routine biohumoral exams, electrocardiogram and chest X-ray. Subsequently they underwent intermittent nocturnal peritoneal dialysis with a changing cycle of 6-12 hours per session. After 5 days, subjects were checked through echocardiogram and abdominal ultrasound.
Results. The patients mean age was 56.7+/-3.2 years. After ultrafiltration, all subjects showed decreased body weight, abdominal circumference and urea; there was an increase of diuresis and Natriuria. Fifteen subjects entered III NYHA class without variation of EF; all of them showed clinical and echographic reduction of ascites. Mean ultrafiltration quantity was 6.084 ml with mean dialysis hours 20; 7.36% of patients had fever that disappared within 24 hours with antibiotic therapy. All subjects referred to feel well and the mean hospitalization period was of 7 day in spite of the usual 22 days
Chronobiology of meningitis
No full textAim. Our study intended to verify the seasonality of aseptic meningitis.
Methods. 156 patients studied. 59 affected by asptic meningitis. All patients submitted to liquor examination and evaluation of its characteristics.
Results. The evaluation of seasonality of aseptic meningitis showed a peak in July. The analysis for gender, showed greater incidence for females in September and for males in June-July.
Conclusion. We can conclude that aseptic meningitis has greater incidence in summertime
Is radiation a risk factor for atherosclerosis'An echo-cor Doppler study on Hodgkin and non Hodgkin patients.
No full textAims and background: The aim of the present paper was to
study the role of irradiation in the atherosclerotic process in
patients affected by Hodgkin and non-Hodgkin lymphoma.
Methods: We studied 84 subjects, 42 with Hodgkin or non-
Hodgkin disease and 42 controls. All 42 cases had been irradiated
and were comparable in terms of risk factors for
atherosclerosis. All 84 subjects underwent echo-color
Doppler of the arterial axis (carotids, abdominal aorta, and
femoral arteries), and the intima-media thickness was measured.
Results: The irradiated cases had a greater intima-media
thickness in the carotid district, even after dividing them according
to age and sex; males were affected more than females.
The irradiated patients were at greater risk of developing
cardiovascular events than the controls.
Conclusions: An echo-color Doppler of the carotid district is
advisable in all patients who have been submitted to radiotherapy,
and the patients with a significantly greater than
normal intima-media thickness need a strict follow-up, and
antioxidant or antiaggregant therapy should be considered
Seasonal variation in the incidence of deep vein thrombosis in patients with deficiency of protein C or protein S
No full textI.F. 0.93
Chronobiology of non fatal pulmonary thromboembolism.
No full textBackground. It as been demonstrated that acute myocardial infarction, sudden cardiac death, stroke, and fatal pulmonary embolism show an increased onset rate during certain periods of the day, week, or year. According to some authors, the highest risk appears to occur in the morning, on weekends and during winter. This paper, therefore, intends to examine whether a circadian, weekly, or annual rhythm in the incidence rate of deep vein thrombosis (DVT) and non-fatal pulmonary embolism (PE) in ageing patients does exists. Methods. A survey was conducted into 212 patients affected by DVT and PE, admitted to the Second Medicine Institute of Padua, Italy, over a period of two solar years. Thromboses were diagnosed via echo-Doppler examination of the legs and pulmonary embolism via perfusive and ventilatory scintiphotographs. Results. In the overall sample, a circadian variation was found, both for deep vein thrombosis (peak at 12:26 hrs, p=0.001), and pulmonary embolism (peak at 10:26 hrs, ..
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