1,721,323 research outputs found
Converting enzyme inhibitors for the treatment of hypertension in the elderly.
No full textRecent epidemiological studies have confirmed that high blood pressure increases the risk of cardiovascular morbidity and mortality not only in young and middle-aged subjects but also in elderly patients. For this reason there is an increasing tendency to treat hypertension also in this age group. However in doing so several problems may be encountered, if the particular physiopathological characteristics of these patients are not taken into account. Recently captopril has been proposed as a useful agent in these cases since it does not reduce coronary, cerebral and renal blood flow and does not cause orthostatic hypotension. These properties are of the utmost importance because elderly patients often present a decreased renal function, ischaemic heart disease, cerebrovascular disease and an impaired baroreflex sensitivity. Although to date no controlled studies have been published on the use of captopril in hypertensives over 60 years old, the results of a recent captopril surveillance programme indicate that this agent is efficacious and well tolerated in these patients
La profilassi di recidive del reumatismo articolare acuto
No full textCapitolo circa l'impeigo di alcuni chenioteraopici nella prevenzione delle recidive della malattia reumatica. Disamina sulla malattia reumatica in generale
[Isolated systolic hypertension: epidemiologic aspects, prevention, and risk].
No full textUna trattazione circa l'ipertensione sistolica isolata, antesignana di un tema che sarà poi ampiamente ripreso in tempi più recenti dal prof. Casiglia e dal suo gruppo di ricerca nell'ambito di diversi studi epidemiologici di popolazione
Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma
No full textThe graduation of William Harvey at the University of PAdua and the discovery of circulation (1602-2002)
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Contributo degli studi italiani nei pazienti ipertesi.
No full textUna rassegna dei trials clinici controllati svolti in Italia, in gran parte portati a termine dal gruppo di ricerca di Padova facente capo al prof. Casiglia (Camposampiero, CASTEL, EPOGH, LEOGRA, Mirano, Piove di Sacco). Sono anche descritti i progetti ARCA, Brisighella, ForLife, PAMELA, SILVIA, REACT, Ventimiglia e Vobarno, nonché lo studio HARVEST organizzato a Padova dal prof. Palatini
Primary aldosteronism: an update on screening, diagnosis and treatment
No full textBACKGROUND: Primary aldosteronism is much more common than previously held; it implies an excessive organ damage to the heart, vessels and kidney, which translates into an excess of cardiovascular events. These two features, along with the fact that the arterial hypertension and the hypokalemia can be corrected with a timely diagnosis and an appropriate therapy, warrant an aggressive diagnostic approach in hypertensive patients.
OBJECTIVES: To provide updated information on the screening and exclusion tests for primary aldosteronism and to illustrate the strategy that can be followed for primary aldosteronism subtype differentiation.
DESIGN: Review of the literature and personal experience of the authors.
RESULTS: The available evidence showed that a cost-effective strategy for the screening of patients with primary aldosteronism can be exploited at most centres. At variance, the identification of primary aldosteronism subtypes, for example, the differentiation of patients with an aldosterone-producing adenoma from those with idiopathic hyperaldosteronism should be undertaken at tertiary referral centres.
CONCLUSION: The identification of a curable form of primary aldosteronism can be much rewarding for the patient and the doctor. Thus, an aggressive diagnostic approach is mandatory at least in some subgroups of hypertensive patients who are at higher prior risk of primary aldosteronism or can benefit more from an accurate diagnosis
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