1,720,965 research outputs found
Comparative in vitro activity of silver sulfadiazine, alone and in combination with cerium nitrate, against staphylococci and gram-negative bacteria
Activity of daptomycin against enterococci and coagulase-negative staphylococci (CNS): relationship between CNS susceptibility and slime production
Nonabsorbable disaccharides plus neomycin in hepatic encephalopathy: do they enhance each other?
Ocular infections: antibiotics and bacterial adhesion on biomaterials used in ocular surgery
Lactitol and neomycin: monotherapy or combined therapy in the prevention and treatment of hepatic encephalopathy?
The beneficial effect of disaccharides, lactulose and lactitol, in prevention adn treatment of hepatic encephalopathy is well established but their use in combination with neomycin is still controversial. We studied in vitro the fecal bacterial growth, acid and gas formation in presence of lactitol (beta-galactoside-sorbitol) and neomycin alone or in combination. The results indicate that neomycin only inhibits the growth of susceptible bacteria (E. coli, Staph. aureus) which, conversely, are poor lactitol fermenters. The resistant organisms (Lactobacillus acidophilus, Clostridium perfringens) that are efficient disacchride fermenters continue to metabolize lactitol still when antibiotic is added. Addition of lactitol 10% increaded the inhbitory effect of neomycin on bacterial growth by 25-50% within 60-70 min. These preliminary data suggest that lactitol and neomycin may have additional or symergistic effects in vivo when used together in presence of favourable intestinal microbial environment
Antibacterial activity of 3rd-generation cephalosporins and other antibiotics on recently isolated strains
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