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NECROTISING SIALOMETAPLASIA OF MINOR SALIVAR GLANDS ARISING AFTER SURGERY FOR PERIPHERAL ODONTOGENIC FIBROMA. A POTENTIAL DIAGNOSTIC PITFALL.
No full textMASSIVE OSTEOLYSIS (PHANTOM BONE OR GORHAM–STOUT DISEASE) OF THE MANDIBLE. REPORT OF A CASE.
No full textInfluence of DNA ploidy, pathologic factors, serum CA 19-9 on prognosis of resected pancreatic carcinoma.
No full textMacrocystic serous cystadenoma of the pancreas. Clinicopathologic features in seven cases
No full textBACKGROUND: Serous cystic neoplasms of the pancreas are uncommon tumors classified as microcystic adenomas. In this article, the authors report clinico-pathologic features of seven cases of macrocystic variant of the serous cystadenoma.
METHODS: Seven patients (5 females and 2 males) with a diagnosis of cystic lesion of the pancreas were observed after 1995. Clinical, radiological, and pathologic features, including immunohistochemistry, were reported. Enzymes and tumor markers CEA, CA 19-9, CA 125, CA 15-3, CA 72-4, and mucin-like carcinoma-associated antigen (MCA) were investigated in the serum and cyst fluid of the patients. Cytology was also performed.
RESULTS: Six patients were symptomatic complaining abdominal pain. All cases had radiologic evidence of unilocular cyst of the pancreas. The suspected diagnosis was consistent with mucinous cystic neoplasm. Serum tumor markers were all in the normal range. After surgery, pathology showed in all cases a cyst lined with cuboidal, periodic acid-Schiff (PAS)-positive epithelium, without mucin content or atypia. Minute microcysts were found surrounding the main cavity. Immunohistochemical stains were positive for cytokeratin, CA19-9, CA15-3, CA 72-4, and MCA. CEA was unexpressed. CA 125 in the cyst fluid were found elevated in three cases and CA 19-9 in three cases. Cytology was negative in all cases.
CONCLUSION: When a unilocular pancreatic cyst is found, without history of pancreatitis and gallstones, having low serum tumor markers levels and negativity of CA 72-4 and MCA in the cyst fluid, the diagnosis of the macrocystic variant of the serous cystadenoma may be suggested. At present, the diagnosis is still based on pathological examination after cyst removal
Influence of DNA ploidy, pathologic factors, serum CA 19-9 on prognosis of resected pancreatic carcinoma.
No full textEffetto della orchiectomia e somministrazione del testosterone nella cancerogenesi pancreatica sperimentale.
No full textSolitary true cyst of the pancreas in adults. Report of three cases and review of the literature.
No full textSolitary true cysts of the pancreas are extremely rare: to date, only eight cases have been reported in the English literature, four of which had clinical significance. An additional three cases of solitary true cysts of the pancreas are presented. One patient was incidentally found at operation, performed for other disease, to have a cystic lesion in the body of the pancreas; the other two patients experienced abdominal pain and nausea. Abdominal US, CT, and MR showed a unilocular cyst in the body and tail of the pancreas. In both cases, preoperative diagnosis of pancreatic cystic neoplasm was made. Two patients underwent excision of the mass and one distal pancreatectomy. Analysis of the cyst fluid revealed high CA 19-9 levels in two and CA 125 levels in one case. All cysts were lined by cuboidal epithelium, without morphological alterations. Preoperative differential diagnosis with the most common cystic pancreatic lesions (inflammatory or neoplastic) is difficult
Lymph node biopsy in the diagnostic and prognostic assessment of patients with HIV infection.
No full textThirty-three anti-HIV positive patients with persistent generalized
lymphadenopathy (PGL) who underwent lymph-node biopsy were studied to assess the
diagnostic and prognostic relations existing between clinical, histological and
laboratory findings. Patients were also examined for known risk factors,
laboratory and bacteriological tests, and mononuclear cell surface marker
analysis. 4 histological types were identified according to Ràcz's
classification. At biopsy, there were 21 cases of LAS (64%), 6 cases of ARC (18%)
and 6 cases of AIDS (18%); a clear prevalence of type 1 was evidenced in LAS/ARC
patients, while only type 4 was present in the AIDS group. An ARC type 3 patient
developed manifest AIDS within 13 months from biopsy. These results suggest that
anti-HIV positive asymptomatic patients with PGL apparently do not require lymph
node biopsy, as none of them showed histologic findings suggestive of
opportunistic infections, malignant lymphoma or Kaposi's sarcoma. On the
contrary, lymph node biopsy can play a diagnostic and prognostic role in anti-HIV
negative subjects with PGL, and in ARC and AIDS patients
Effect of orchiectomy and testosterone replacement on experimental pancreatic carcinogenesis.
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