1,721,070 research outputs found
Contribution of neuromagnetic integrated methods in evaluating cerebral mechanisms of plastic reorganization in monohemispheric stroke
No full text
Coexistence of contralateral cluster headache and probable paroxysmal hemicrania. A case report
Full text linkThe trigeminal autonomic cephalagias are short-lasting unilateral headaches associated with autonomic features. Even if coexistence of different ipsilateral TACs in the same patient has been previously reported in few papers, the simultaneous occurrence of contralateral TACs is not described previously
Evaluation of Stroke
No full textBasic magnetism, Magnetic stimulators and coil design, Activation of peripheral nerve and nerve roots, Activation of brain, TMS, TES, paired pulse, Repetitive TMS, physiology and safety, Central motor conduction and its clinical applications, Evaluation of radiculopathy, thoracic nerve, and myelopathy, Evaluation of cauda equina, Cranial nerve, Plasticity, ALS, Motor system physiology, Evaluation of movement disorders, Fatigue, Treatment of motor disorders; Evaluation of stroke, Evaluation of epilepsy and anticonvulsants, Language, Other cognitive functions, Pathophysiology of psychiatric disorders/steroids, Psychiatric therapy, Visual system, Somatosensory system, Eye movements, Spinal cord monitoring, Phrenic nerve, Function stimulation in spinal cord injury, Migraine, Sleep/RLS, TMS in childre
Neuromagnetic integrated methods tracking human brain mechanisms of sensorimotor areas 'plastic' reorganisation.
No full textThe potential for reorganization in the adult brain has been largely underestimated in the past and we are just beginning to understand the organisational principles involved in functional recovery. A bulk of experimental evidences have been accumulated in support of the hypothesis that neuronal aggregates adjacent to a lesion in the cortical brain areas can be progressively vicarious to the function of the damaged neurones. Such a reorganisation, if occurring in the affected hemisphere of a patient with a monohemispheric lesion, should significantly modify the interhemispheric symmetry of somatotopic organisation of the sensorimotor cortices, both in terms of absolute surfaces and number of 'recruited' neurons, as well as of spatial coordinates. In fact, a roughly symmetrical organisation of sensorimotor - particularly for the hand contorl - in the right and left hemisphere has been observed in healthy humans by different methods of functional brain imaging, including fMRI, TMS, MEG, HD-EEG. Not uniform results about the functional brain activity related to sensory, motor and cognitive functions in normal and diseased subjects are often due to differences in the experimental paradigm designed as well as in the spatial and temporal resolution of the neuroimaging techniques used. The multi-modal integration of data obtained with several neuroimaging techniques allowed a coherent modelling of human brain higher functions. Functional magnetic resonance imaging (fMRI) provided fine spatial details (millimetres) of the brain responses, which were compared with the cortical maps of the motor output to different body districts obtained with transcranial magnetic stimulation (TMS). Magnetoencephalography (MEG) ability to study sensorimotor areas by analysing cortical magnetic fields, is also complementary to the motor cortex topographical mapping provided by TMS. MEG high temporal resolution allows to detect relatively restricted functional neuronal pools activated during cerebral processing of external stimuli. Moreover, these brain responses can be investigated with magnetoencephalography (MEG) and high density electroencephalography (EEG) techniques, with elevated time resolution (ms). With respect to the high resolution EEG technique, the MEG technique allowed a more precise localisation of the sites of neural activity buried into the cortical sulci, but was unable to detect the response of the crown of the cortical giri and of the frontal-mesial cortex (including the supplementary motor area), because of its poor sensitivity to radially oriented dipoles. The integration of functional and anatomical information provide cues on the relationship between brain activity and anatomic sites where this takes place, allowing the characterisation of the physiological activity of the cortical brain layers as well as to study the plastic reorganisation of the brain in different pathological conditions following stroke, limb amputation, spinal cord injury, hemisperectom
- …
