1,721,562 research outputs found
Prevention of erlotinib-induced folliculitis with doxycycline
Deplanque et al. (2016) reported their experience after doxycycline
administration in the prevention of erlotinib-induced folliculitis in
patients affected by non-small-cell lung cancer (NSCLC). The oral epidermal
growth factor receptor (EGFR), tyrosine kinase inhibitor erlotinib,
is a second-line monotherapy for advanced NSCLC in patients with
disease progression after first-line platinum-based therapy, recently
approved also as first-line treatment for patients with EGFR mutationpositive
NSCLC. Erlotinib is generally well tolerated. The most common
side effects include skin toxicity, such as rash (folliculitis or acneiform
rash/papulopustular eruption), xerosis, paronychia, pruritus, hair
growth, and ocular disorders. Cutaneous adverse events may prejudice
patient compliance, leading to dose reduction, treatment delay, or
withdrawal.
The authors randomized patients into two group
Dermatite atopica 2016-2017 (sidemast). revisione critica di linee guida e raccomandazioni pratiche per la gestione dei pazienti con dermatite atopica
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New data on the use of the FISH technique: the horizon dividing Spitz nevi and melanoma in childhood moves even further away
Efficacy and tolerability of supplementation with Polinacea® and AM3® in the clearance of ano-genital warts: a single-center observational study in adults
Visualization of hair bulbs through the scalp: A trichoscopic feature of erosive pustular dermatitis of the scalp
Erosive pustular dermatitis of the scalp (EPDS) typically affects elderly people with scarring alopecia. Videodermoscopy (VD) of the scalp has never been assessed in the diagnosis of EPDS. To evaluate the trichoscopy features of EPDS, we carried out a retrospective analysis of VD images obtained in the scalp of ten patients who affected by EPDS and were compared with those obtained from a series of thirty patients who affected by other type of scarring alopecia. The most specific VD feature was thus represented by evident hair bulb in the scarring scalp, observed in all patients
Acquired hypertrichosis localized on a subsiding psoriatic plaque after plaster application
Postcast hypertrichosis is a common transient occurrence in orthopedic patients and generally resolves within a few months. Until now, two cases of localized hypertrichosis occurring on more than one pre-existing psoriatic lesions are reported in the literature. We describe the case of a patient who simultaneously developed a single psoriatic plaque and overlying localized hypertrichosis after plaster application. This concurrence is exceptional and may be explained by the expression of several growth factors and cytokines influencing both the hair cycle and the psoriatic inflammatory working
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