36,455 research outputs found
CROSSING-SYMMETRIC DESCRIPTION OF COMPLEX K+K-PI-PN-
No full textHOYER P, Petersson B, LEA AT, PATON JE, THOMAS GH. CROSSING-SYMMETRIC DESCRIPTION OF COMPLEX K+K-PI-PN-. Nuclear Physics B. 1971;32(1):285-305
Woud: Trek je even terug in je concentratiebubbel
No full textHet was zo’n zonnige lentedag; heerlijk om lekker buiten te zijn. Ik zat binnen, in een vergadering – met de nodige moeite om mijn aandacht erbij te houden. Liever keek ik door het raam naar kersenbloesems. Afgeleid raken, wegdromen ofjuist onrustig zijn en niet stil kunnen zitten. Herkenbaar? Vast wel; iedereen heeft wel eens moeite om zich te concentreren. Maar voor sommige kinderen is dit een dagelijkse worsteling. Hoe ga je daar op een goede manier mee om in eenklaslokaal, een omgeving met constante prikkels en afleiding? Ontwerper Shion Ito ontwierp een mini-bos waar je je even in kunt terugtrekken om je rust terug te vindenGreen Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Human-Centered DesignDesign Aesthetic
Effects of tuberculosis and HIV infection on whole-body protein metabolism during feeding, measured by the [15N]glycine method
No full textBackground: Tuberculosis (TB) and HIV infection are wasting diseases that frequently occur together and have severe consequences on nutritional status.Objective: The objective was to determine the effects of TB and HIV, separately and together, on protein metabolism.Design: Protein metabolism was determined in the fed state in 11 healthy control subjects, in 10 patients with HIV infection without TB or other active infection (HIV group), in 10 patients with active TB without HIV infection (TB group), and in 8 patients with HIV infection and active TB (HIVTB group) with the use of oral [15N]glycine and measurement of enrichment in urinary urea and ammonia.Results: Whole-body protein flux and degradation were lower in the HIV group than in the control group (mean flux: 3.53 ± 0.40 compared with 4.75 ± 0.97 g · kg lean body mass-1 · 12 h-1; P = 0.002). Protein flux, synthesis, and degradation were not significantly different between the control group and the TB and HIVTB groups. Net protein balance was strongly anabolic in the control, HIV, and TB groups but was neutral in the HIVTB group (P < 0.001 for comparison between groups).Conclusions: HIV infection was associated with a significant down-regulation of whole-body protein flux. TB alone was not associated with abnormal protein metabolism, but net anabolism in the fed state was impaired in the HIVTB group
Professor Sir William Paton CBE FRS in interview with Dr Max Blythe: Part 2
No full textAt the start of the interview Sir William Paton, professor of Pharmacology at Oxford 1959-84 talks about his childhood and education, and the decision to study medicine at Oxford. He speaks of his tutors at New College - the physiologist RS Creed and the theologian RH Lightfoot - and organ lessons with Sydney Watson. Sir William then discusses his clinical studies at University College Hospital from 1939: a year in Cardiff to avoid heavy bombing, the influence of Max Rosenheim, the experience of being a medical student in London during the war. House jobs followed, then a bout of pneumonia, which he had already had several times, ruled out residential clinical positions, so he worked for a year as a pathologist at the TB sanatorium at Midhurst. Next, Sir William reflects on his work at the National Institute of Medical Research from 1944 to 1952. He acknowledges the effective leadership of GL Brown and FC Macintosh. Early physiological research into diving problems, including decompression sickness and the escape from submarines by free ascent, his move to pharmacology - working on methonium compounds with Eleanor Zaimis, and collaborating with anaesthetist Geoffrey Organe - and the impact of the move to Mill Hill in 1949 on the atmosphere at the Institute, are outlined. Then there is discussion of developments in British pharmacology: the low status of the discipline for many years, the influence of JH Gaddum, and the early years of the British Society of Pharmacology. In 1952 Sir William moved to UCH as reader in applied pharmacology. He talks of his teaching, which attempted to bridge the gap between basic preclinical pharmacology and therapeutics, and his research on histamine distribution and, with John Thompson, on porphobilinogen. Next, Sir Wiliam reflects on his five years as the first Vandervell professor of pharmacology at the Royal College of Surgeons. He outlines the challenges of setting up new department, developing a laboratory and building up a team of researchers - John Thompson, JE Gardiner, John Vane at first, later joined by Ted Marley and James Greig Murray - who all worked with one another. He also speaks of postgraduate teaching and research in this period, particularly development of the coaxially stimulated ileum preparation, continued physiological research on diving problems, histamine work, and developing the rate theory of drug action. At the end of the interview, Sir William looks back on his appointment as professor of pharmacology at Oxford in 1959, and his first task there, overseeing the building of a new pharmacology lab
ANDREW ARCHIBALD PATON: LIKA AND SENJ IN A TRAVELOGUE FROM 1849
No full textVeliko zanimanje engleskih putopisaca već od kraja XVIII., a posebno početkom i
sredinom XIX. stoljeća za istočnojadransku obalu kulminiralo je krajem toga i početkom
sljedećega stoljeća. Motivi putovanja su različiti: od upoznavanja "egzotičnih" krajeva,
otkrivanja nepoznate europske kulturne baštine, pa sve do ciljanoga snimanja stanja i
odnosa političkih snaga u Austrijskome carstvu, njegovom odnosu prema susjednome
Otomanskom carstvu te jačanja samosvijesti slavenskih naroda u odnosu na mađarski i
austrijski hegemonizam i slavenske narode u Otomanskom carstvu. Britanski diplomat,
tajni obavještajac britanskoga veleposlanstva u Beču, sa znatnim vojno-diplomatskim
iskustvom na Bliskom istoku (Sirija, Egipat) i u Srbiji Andrew Archibald Paton (1811.
– 1874.) proputovao je 1846. i 1847. godine istočnojadranskom obalom, Dalmatinskom
Zagorom i Likom prvenstveno sa zadatkom prikupljanja podatka o materijalnom stanju
toga dijela Austrijskoga carstva, posebno istočnojadranskih luka. Putovanje je započeo
kočijom iz Beča u Zadar, nastavio do Kotora, posjetio Crnu Goru te se vratio u Zadar
odakle je preko Like otputovao za Rijeku, Trst i završio u Grazu. Istražujući te krajeve
Paton je dokumentarnom preciznošću opisao ljude i krajeve riječju i slikom, bilježio
neke detalje iz kulturne baštine i lokalne povijesti, koje je uglavnom pabirčio iz putopisa
prethodnih britanskih posjetitelja, kao i prirodne fenomene i ljepote krajolika za što je
pokazao i dosta literarnoga smisla. To je objavio u kapitalnom djelu: Highlands and
islands of the Adriatic: including Dalmatia, Croatia, and the southern Provinces of
the Austrian Empire, Volumen I. i II., koje je 1849. godine objavio u Londonu. Ovo je
djelo poslovna i politička javnost dobro primila i Paton već 1862. godine objavljuje u
Londonu prošireno izdanje Researches on the Danube and the Adriatic; or, Contributions
to the Modern History of Hungary and Transylvania, Dalmatia and Croatia, Servia and Bulgaria. 2 vols., u kojem Paton daje zemljopisno - povijesni pregled jugoistočne
Europe, svoja zapažanja, posebno ekonomska i politička gledanja na zatečene prilike i
budućnost tih zemalja. Patonov opis Like i Senja nije opsežan, već je jezgrovit, kritičan i
pun osobnih promišljanja o trenutnom stanju, kao i o potencijalima tih krajeva. Njegovi
opisi su dragocjeni podaci i svjedočanstva o krajevima i ljudima i nisu samo povijesna
dokumentacija, već je to i uvid u poglede i mišljenje drugih, stranaca o tim krajevima i
ljudima. To je dokumentacija koja je bitno utjecala i postupno oblikovala javno mnijenje
engleskoga govornoga područja i šire. Danas su nam ti stavovi i mišljenja pomalo
čudni, često nerazumljivi i neprihvatljivi, a tako su znatno utjecali na političke odluke
anglosaksonskih zemalja (Velika Britanija, SAD) i njihovih sljedbenika u prošlosti,
a mogu se i danas prepoznati u političkim, gospodarskim i kulturnim htjenjima i
postupcima tih država, posebno Velike Britanije. U ovome radu autor donosi u prijevodu
dijelove toga djela s opisima Like i grada Senja s komentarima i potrebnim pojašnjenjima
te dosta opširnu bibliografiju britanskih i američkih autora koji su posjetili ili pisali o
hrvatskim krajevima od kraja XVIII. do početka XX. stoljeća.The great interest of English travel writers from the end of the 18th century, and especially
from the beginning and mid-19th century in the Eastern Adriatic coast culminated at the end
of it and at the beginning of the 20th century. The motives for travelling were varied: from the
familiarisation of "exotic" regions, the discovery of unknown European cultural heritage, all the
way to the targeted recording of the conditions and relationships of political powers in the Austrian
Empire, its relationship with the neighbouring Ottoman Empire, and the strengthening of the selfconfidence
of the Slavic peoples in relation to the Hungarian and Austrian hegemony and the Slavic
peoples in the Ottoman Empire. British diplomat, secret intelligence officer of the British Embassy
in Vienna, with significant military-diplomatic experience in the Middle East (Syria, Egypt) and
in Serbia, Andrew Archibald Paton (1811-1874) travelled, in 1846 and 1847, the Eastern Adriatic
coast, the Dalmatian Hinterland (Zagora) and Lika primarily with the task of gathering information
about the material condition of that part of the Austrian Empire, especially the Adriatic ports. He
began the journey began by carriage from Vienna to Zadar, continued to Kotor, visited Montenegro
and returned to Zadar from where, via Lika, he travelled to Rijeka, Trieste and ended in Graz and
Vienna. He was the first Briton to visit the interior of Croatia, particularly the Military Frontier and
Lika. Exploring these regions Paton described with documentary precision the people and regions
with words and pictures, he noted some details from the cultural heritage and local history, which
he mostly gleaned from the travelogues of previous visitors and literature which he was able to
consult in Vienna. He also described the natural phenomena (Plitvice Lakes) and the beauty of the
landscape (Plješivica, Velebit) for which he also demonstrated a fair amount of literary penchant.
Particularly interesting are his descriptions of the towns (Gospić, Otočac, Senj), as well as smaller
places – villages (Vrhovine, Korenica, Zavalje). He published this in a major work: Highlands and
islands of the Adriatic: including Dalmatia, Croatia, and the Southern Provinces of the Austrian
Empire Highlands and islands of the Adriatic: including Dalmatia, Croatia, and the Southern
Provinces of the Austrian Empire, Volumes 1 and 2, which he published in London in 1849. This
work by received well by the business, political and public readership and by 1862 Paton published
an expanded edition in London - Researches on the Danube and the Adriatic; or, Contributions
to the Modern History of Hungary and Transylvania, Dalmatia and Croatia, Servia and Bulgaria
2 volumes, in which Paton describes the geographical-historical look of South East Europe, his
observations, especially the economic and political views of the existing conditions and future of
these countries. Paton’s description of Lika and Senj is not extensive, but it is concise, critical and
full of personal ponderings about the current situation, as well as the potentials of these regions.
His descriptions are invaluable information and testimonies about the regions and people, and
they are not only historical documents, but it is also an insight into the views and thoughts of
others, foreigners about these regions and peoples. It is the documentation which significantly
influenced and gradually formed the public opinion of the English-speaking regions and further
afield. For us today these attitudes and thoughts are slightly strange, often incomprehensible and
unacceptable, and so they significantly influenced the political decisions of Anglo-Saxon countries
(Great Britain, the USA), and of their adherents in the past, and they can also be recognised in the
political, economic and cultural intentions and procedures of these countries, especially of Great
Britain. In this paper the author provides a translation of parts of this work with descriptions of
Lika and the town of Senj with comments and the necessary explanations, plus a quite extensive
bibliography of British and American authors who had visited and written about the Croatian
regions from the end of the 18th century to the beginning of the 20th century
Londen laat zien: verstedelijking kun je privaat bekostigen
No full textSimon van Zoest en Tom Daamen doen bij de leerstoel Gebiedsontwikkeling onderzoek naar de financiering en bekostiging van grootstedelijk openbaar vervoer. Zij kijken daarbij voorbij de instrumenten en verdiept zich in de motieven en succesfactoren achter de invoer van alternatieve bekostiging. Zo maakt Londen duidelijk dat een private bijdrage aan ov-investeringen mogelijk én wenselijk kan zijnPractice Chair Urban Area DevelopmentUrban Development Managemen
Tam Tam in je broekzak
No full textDit is het eindverslag van de stage "Tam Tam in je broekzak", die wij hebben uitgevoerd in het kader van IN3405 Bachelorproject. Deze stage is uitgevoerd bij Tam Tam B.V. te Rijswijk.Technische InformaticaComputer ScienceElectrical Engineering, Mathematics and Computer Scienc
Melk in je koffie: Een onderzoek met mogelijkheden
No full textIn 1999 stond in de NRC een column van Karel Knip over de vraag uit de wetenschapsquiz of je direct een wolkje melk in je koffie moet doen als de bel gaat of dat je dat beter kunt doen als je terugkomt van de buitendeur. De column geeft een mooi beeld van wat er allemaal kan komen kijken als je wat dieper op de vraag ingaat. Er blijken veel mogelijkheden te zijn om ook in de klas met deze vraag aan de slag te gaan!ImPhys/Docente
Zo meet je de waarde van sociale investeringen
No full textWat leveren investeringen in de zachte, sociale kant van gebiedsontwikkeling op? Deze vraag houdt ontwikkelaars, gemeenten en beleggers al langer bezig. Een antwoord is te vinden via de capability-benadering. Hierbij staan niet de kwantitatieve fysieke functies centraal, maar de kwalitatieve mate waarin mensen in staat zijn deze te gebruiken.Practice Chair Urban Area Developmen
Als je oud wordt moet je de buurt uit
No full text"Als je oud wordt moet je de buurt uit" is een beschrijving van een planologisch onderzoek onder ouderen in de Da Costabuurt, een stadsvernieuwingsbuurt in Amsterdam Oud-West. Ervaringen en meningen van ouderen zij het uitgangspunt van dit onderzoek. Door groepsgesprekken en individuele interviews worden de knelpunten die zij ervaren in het zelfstandig wonen geïnventariseerd. Daaruit blijkt dat deze knelpunten zo urgent zijn, dat vele ouderen hierdoor worden gedwongen uit de buurt te verhuizen. In de aanbevelingsfeer ligt de nadruk op het versterken van de positie van ouderen in het stadsvernieuwingsproces. Ouderen zullen zich als groep actiever moeten opstellen, om meer greep te krijgen op de inrichting van hun directe omgeving.Delft University of Technolog
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